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The Second World War gave rise to a previously inconceivable number of peripheral nerve injuries. Besides in most cases the defect of substance is not as great as in war injuries, in which the so-called "critical resection length" (Seddon) was the cause of the greatest difficulties and consti tuted the crucial obstacle to good success.

I am convinced that a very important task of experimental medical research is to find applications to the relevant clinical problem as soon as possible, and to avoid distraction by an increasingly over whelming accumulation of new information from all fields of scientific work.

Microdialysis is a minimally invasive method which enables continuous monitoring of parameters in the extracellular space of various tissues. In 1994 we thought that research on clinical microdialysis had reached the stage which would enable scientists and clinicians to have many fruitful discussions.

Bilateral lesions of effective size are difficult to achieve without side effects, particularly in respect of speech (notably dysarthria) and yet are essential if intractable epilepsy is to be con trolled in severity and frequency.

The book gives the most up-to-date information for the expanding field of stereotactic and functional neurosurgery from European and international experts.