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While discussion concerning the validity of the plant approach to nutrition and disease treatment continues, the explosion of natural product use has generated concern regarding their effectiveness and possible danger. Using a rational, sequential approach, this book explores the development of efficacious medicinal herbal products.

This book focuses on recent developments in understanding human genome interactions with various natural products. It includes studies on the interaction of natural products with genes involved in diseases such as breast and prostate cancer, as well as the effects of natural products on microbial growth. It also presents a unique real-time approach by providing hyperlinks to websites with updated literature on natural products and interactions with genes involved in metabolic pathways.

This reference provides an up-to-date compilation of background scientific information that advocates the application of currently developed clinical studies of the effects of aromatherapy to the treatment of human diseases such as mild, stress-induced mood disorders, infectious diseases, and age-related disturbances. It presents a rational basis for clinical translations of aromatherapy for treating human diseases in need of safer or more effective therapies and discusses the need for further clinical development in areas where therapy is lacking.

This unique volume provides the latest information on secondary metabolites obtained from selected organisms (plants or microorganisms) that have beneficial effects in the treatment of cardiovascular diseases and an ability to offer protection against their progress. A detailed description of their source, chemistry and mechanism of action is provided, together with results of clinical studies. Here, a clear connection is made between chemical structures, in vitro studies and their clinical significance.The topic is extensive and the audience gains an understanding of the medicinal applications of these groups of secondary metabolites that have the potential to improve cardiovascular health.

The purpose of this book is to focus on major considerations in the clinical use of botanicals and on the best evidence with botanical therapies as an integrated approach to health care globally. The editors here cover the key areas, ensure a global focus and include epidemiological studies. There are relevant sections on the chemical constituents of the various botanicals to round out the pharmacognosy aspects of the book. Finally, a summary on the editors' perspective of "challenges and opportunities" is provided, which discusses the practice of botanicals as integrative therapies and where they are heading in the future.

Herbal Medicines: Development and Validation of Plant-Derived Medicines for Human Health takes readers on a rational path for development of efficacious medicinal herbal products.