Bøker i Computational Neuroscience Series-serien

Churchland and Sejnowski address the foundational ideas of the emerging field of computational neuroscience, examine a diverse range of neural network models, and consider future directions of the field.

A textbook for students with limited background in mathematics and computer coding, emphasizing computer tutorials that guide readers in producing models of neural behavior.This introductory text teaches students to understand, simulate, and analyze the complex behaviors of individual neurons and brain circuits. It is built around computer tutorials that guide students in producing models of neural behavior, with the associated Matlab code freely available online. From these models students learn how individual neurons function and how, when connected, neurons cooperate in a circuit. The book demonstrates through simulated models how oscillations, multistability, post-stimulus rebounds, and chaos can arise within either single neurons or circuits, and it explores their roles in the brain. The book first presents essential background in neuroscience, physics, mathematics, and Matlab, with explanations illustrated by many example problems. Subsequent chapters cover the neuron and spike production; single spike trains and the underlying cognitive processes; conductance-based models; the simulation of synaptic connections; firing-rate models of large-scale circuit operation; dynamical systems and their components; synaptic plasticity; and techniques for analysis of neuron population datasets, including principal components analysis, hidden Markov modeling, and Bayesian decoding. Accessible to undergraduates in life sciences with limited background in mathematics and computer coding, the book can be used in a "flipped” or "inverted” teaching approach, with class time devoted to hands-on work on the computer tutorials. It can also be a resource for graduate students in the life sciences who wish to gain computing skills and a deeper knowledge of neural function and neural circuits.

The complexity of the brain and the protean nature of behaviour remain the most elusive area of science, but also the most important. Written by 23 experts from many areas of systems neuroscience, this book provides a useful roadmap to the field of systems neuroscience, and aims to serve as a source of inspiration for explorers of the brain.

Using experimental and theoretical findings from cellular biophysics, this book explains the computational functions of single neurons. The topics include the linear cable equation; cable theory as applied to passive dendritic trees and dendritic spines; and chemical and electrical synapses and how to treat them from a computational point of view.

This book is concerned with sensory cue integration both within and between sensory modalities, and focuses on the emerging way of thinking about cue combination in terms of uncertainty. The probabilistic approaches elaborated in Sensory Cue Integration aim to formalize the uncertainty of cues. They describe cue combination as the nervous system's attempt to minimize uncertainty in its estimates and to choose successful actions.

This volume, on unsupervised learning algorithms, focuses on neural network learning algorithms that do not require an explicit teacher. The goal of unsupervised learning is to extract an efficient internal representation of the statistical structure implicit in the inputs. These algorithms provide insights into the development of the cerebral cortex and implicit learning in humans. They are also of interest to engineers working in areas such as computer vision and speech recognition who seek efficient representations of raw input data.

An introduction to the computational biology of reaching and pointing, with an emphasis on motor learning.

A mathematical framework that describes learning of invariant representations in the ventral stream, offering both theoretical development and applications.

A practical guide to neural data analysis techniques that presents sample datasets and hands-on methods for analyzing the data. As neural data becomes increasingly complex, neuroscientists now require skills in computer programming, statistics, and data analysis. This book teaches practical neural data analysis techniques by presenting example datasets and developing techniques and tools for analyzing them. Each chapter begins with a specific example of neural data, which motivates mathematical and statistical analysis methods that are then applied to the data. This practical, hands-on approach is unique among data analysis textbooks and guides, and equips the reader with the tools necessary for real-world neural data analysis.The book begins with an introduction to MATLAB, the most common programming platform in neuroscience, which is used in the book. (Readers familiar with MATLAB can skip this chapter and might decide to focus on data type or method type.) The book goes on to cover neural field data and spike train data, spectral analysis, generalized linear models, coherence, and cross-frequency coupling. Each chapter offers a stand-alone case study that can be used separately as part of a targeted investigation. The book includes some mathematical discussion but does not focus on mathematical or statistical theory, emphasizing the practical instead. References are included for readers who want to explore the theoretical more deeply. The data and accompanying MATLAB code are freely available on the authors' website. The book can be used for upper-level undergraduate or graduate courses or as a professional reference.A version of this textbook with all of the examples in Python is available on the MIT Press website.