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An invaluable guide to successful practice in neglected tropical diseases (NTDs) and highlights best practice to guide the ongoing drug discovery effort.

With perspectives from academia and industry across a spectrum of techniques, this is a go-to volume for biophysicists, analytical chemists and medicinal chemists looking for a broad overview of techniques of contemporary interest in drug discovery.

Written by medicinal chemists and ADMET scientists with a combined experience of over 300 years this aid to discovering drugs provides detailed coverage on absorption, distribution, metabolism, excretion and toxicology issues associated with new drugs.

Advances in Nucleic Acid Therapeutics provides a broad overview of techniques of contemporary interest in drug discovery.

Antibody-drug conjugates are a promising areas of anticancer drug discovery, conveying several advantages, including the ability to select likely responders, efficient delivery of cytotoxic agents and reduced toxicity. This book describes payloads used to date and novel payloads that may be used clinically in the future.

New Tools to Interrogate Endocannabinoid Signalling comprehensively covers the innovative research into both natural and synthetic compounds. This timely volume will be a valuable resource to pharmaceutical researchers and medicinal chemists working in natural products and endocannabinoid drug discovery in academia and industry.

A volume that will provide a mechanism-based approach to understanding Chinese medicine for both Western and Eastern scientists.

Accounts in Drug Discovery describes recent case studies in medicinal chemistry with a particular emphasis on how the inevitable problems that arise during any project can be surmounted or overcome.

Describes proteolytic enzymes and their biological function to aid drug discovery by detailing methods of production and assay of the enzymes.

This exemplary book gives an up-to-date perspective on the role of metal ions in neurodegeneration.

This thorough and up-to-date insight into predictive technologies considers what is on the horizon for safety prediction in human health.

Shows how different parts of the drug discovery process have developed, with particular emphasis on quantitative aspects and possible future progress.

This is the first book to examine the future opportunities and challenges in the development of drugs which target kinases

This book considers the relationship between structure and function in G protein-coupled receptors (GPCRs) and the implications for drug design.

This is the first comprehensive description of the discovery and therapeutic potential of polyamine drugs.

The Medicinal Chemist's Guide to Solving ADMET Challenges presents state-of-the-art design strategies by a global group of experienced medicinal chemists and ADMET experts across academia and the pharmaceutical industry.

This book will act as a primer for graduates and postgraduates interested in a career in drug discovery. It covers both synthetic technologies currently impacting medicinal chemistry and emerging areas.

This volume describes the discovery and development history of the most promising drugs now in development for combating Alzheimer's disease.

This book will review macrocycles in drug discovery and will be of interest to biochemists, pharmaceutical scientists and medicinal chemists working in industry or academia.

This book is aimed at both graduates and postgraduates interested in a career in the pharmaceutical industry by informing them about the breadth of the work carried out in chemical research and development departments. It is also of great value to academics wishing to advise students on the merits of careers in chemical development over discovery.

This unique book focuses on the currently 'hot topic' of Pharmaceutical Salts and Co-crystals. Combining both reports of the latest academic research and comprehensive overviews of basic principles, with more applied contributions from selected experts in industry.

This book, aimed at academics, industrialists and post-graduates, documents the latest research into computer aided drug design.

A rapidly growing field, this book covers the recent advances in screening technology, ion channel structure and modelling, with up-to-date case histories.

An integrated review of the most recent trends in natural products drug discovery and key lead candidates that are outstanding for their chemistry and biology in novel drug development.

This is a wide scope and in-depth coverage of the state of the art and future directions in drug discovery for major psychiatric disorders.

This is the first book to pull together studies and reviews from cutting edge authors who work in the emerging and exciting field of multi-targeted drug discovery.

Anti-Inflammatory Drug Discovery provides a comprehensive review of recent medicinal chemistry approaches to a variety of important therapeutic targets

This book covers proteomics biomarker discovery and validation procedures from the clinical perspective.

This book will provide an invaluable guide to epigenetics, one of the fastest moving fields in drug discovery, for medicinal chemists working in academia and in the pharmaceutical industry.

This book will provide an overview of the chemistry of nanocarrier design and the considerations that need to be made when developing a nanomedicine.