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This book discusses the current status of cellular therapy for neurological disorders. The primary areas of focus include traumatic brain injury, stroke, and spinal cord injury. The book explores cell therapy approaches to these and other conditions, while discussing current advances and a literature review in the context of a field that is moving rapidly. It presents a translational focus, addressing barriers and opportunities to moving forward. The mechanisms of injury are explored, as well as how these mechanisms influence the type of cell therapy used, the route of delivery, and dosing regimen.
The placenta is a source of non-embryonic (i.e. not from the embryo or fetus) stem cells that can be used for research and potentially for a variety of therapies. Stem cells can be harvested following birth, thus avoiding some of the ethical/moral concerns. This book is devoted to the therapeutic and research potential uses for stem cells. It also provides a review of the development, structure, and function of the placenta.
This book will review the life history and immune responses to adenoviruses as well summarize various therapies implemented with the use of adenoviruses.
This book summarizes rapid progress and innovation in transplantation and regenerative medicine - the merger of reconstructive plastic surgery and transplantation - called Vascularized Composite Allotransplantation. This merger includes a wide variety of previously impossible translplantations using grafts derived from organ donors.
The authors offer novel insights into bioreactor-based culture systems specific for tissue engineering, including sophisticated and cost-effective manufacturing strategies geared to overcome technological shortcomings that currently preclude advances towards product commercialization.
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