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To all readers, we present this handbook as a progress report, recognizing that the present state of the ?eld is much farther along than it was the last time a handbook was published, but mindful of the likelihood that it is not as far along as it will be when the next handbook is prepared.

Based on a large variety of experiments on both humans and animals, this volume presents novel conceptualizations of the organizing consequences of hormones throughout the lifespans of mammals.