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Actin Cytoskeleton in Cancer Progression and Metastasis - Part A, Volume 355 in the International Review of Cell and Molecular Biology series, provides an overview of the roles of the actin cytoskeleton and some of its key structural regulators, including WASp, Paxillin, Myosin, Testin, L-Plastin and profilin, in central processes underlying cancer progression and metastasis, such as changes in cell morphology and gene expression, acquisition of migratory and invasive capabilities, and evasion from the immune response. Provides comprehensive and timely reviews on actin cytoskeleton and its regulators in cancer biologyOffers a wide range of perspectives for basic and translational researchDiscusses opportunities and challenges for translating knowledge of tumor cell actin cytoskeleton into clinical applications

Presents advances and comprehensive reviews in cell biology - both plant and animal. This book includes articles that address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth.

Suitable for advanced undergraduates, graduate students and professional scientists, this book presents advances and comprehensive reviews in cell biology - both plant and animal. It provides up-to-date information and directions for future research.

Cell Death Regulation in Health and Disease - Part C, Volume 353 in the International Review of Cell and Molecular Biology series, reviews and details current advances in cell and molecular biology. The IRCMB series maintains the highest standard by publishing timely topics authored by prominent cell and molecular biologists, with this release covering Developmental and seasonal regulation of neural cell death in birds, Post-translational modifications in cell death regulation, The role of cell death in tissue regeneration and fibrosis, Crosstalk between the apoptosis and autophagy signaling pathways, IP3 receptor signal integration in cell death and survival decisions, and more. Provides a comprehensive collection of front-of-the line research in the field of cell death regulationAuthored by established and active cell and molecular biologists drawn from international sourcesIncludes only invited review articles, covering selected topics in many different organisms and disease settings

Nucleic Acid Sensing and Immunity - PART B, Volume 345 gives a comprehensive overview of the nucleic acid machinery, from plants to mammalians, along with their regulation. Chapters in this updated volume include Nucleic acids sensing in allergic disorders, Nucleic acids sensing in autoimmune disorders, Nucleic acid sensing in inflammatory disorders, Viral nucleic acid sensing inflammasomes in intestinal host defense, Genome damage sensing leads to tissue homeostasis in Drosophila, Nucleic acids sensing in plants, Nucleic Acid sensing in invertebrates, amongst other topics.Provides an accurate, state-of-the-art resource on RNA sensingIncludes the work of a well-known tumor immunologist Links intestinal host defense and viral nucleic acid sensing Presents a chapter on the negative regulation of DNA sensing, a timely topic

Biology of T Cells - Part B, Volume 342, the latest release in the International Review of Cell and Molecular Biology series, offers an overview of the major molecular and cellular aspects of T-cell biology and their links to human pathophysiology. Chapters in this release include Metabolism of T lymphocytes in health and disease, T lymphocytes and autoimmunity, Cancer immunosurveillance by T cells, T lymphocytes as targets in viral disorders, Molecular mechanisms underlying pharmacological immunosuppression, T lymphocyte-based immunotherapeutics, In silico methods to analyze T cell biology, and Engineering Platforms for T Cell Modulation. Contains individual chapters that focus on one specific facet of the development, phenotype, function, study or pathophysiological relevance of T lymphocytesPresents the latest release in the International Review of Cell and Molecular Biology series