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Ricardo is making himself sick over his obsession with the girl next door and Elias is hopelessly infatuated with a local prostitute. One lives in the bustle of Mexico City, the other in the quiet of a tiny Baja California town. They both find themselves in a world dominated by desire where "love begins to wither from the moment it takes root".

Mexico, 1991: Black acid rain falls on "Makesicko City", the most polluted, most populated city in the world. Amid this apocalyptic landscape a prize is being offered to the first child born on the 500th anniversary of Columbus' discovery of America. That child is the narrator of this passionate, savage novel by one of the world's preeminent writers.

A modern epic on a grand scale, Avalovara is a rich and lyrical novel centered around Abel's courtship of three women. He pursues the sophisticated and inaccessible Roos across Europe; falls in love with Cecilia, a carnal, compassionate hermaphrodite; and achieves a tender, erotic alliance with a woman known only by an ideogram. Avalovara is an extraordinary novel, both in its depiction of modern life and in its rigorous, puzzlelike structure visually represented by a spiral and a five-word palindrome.