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Dedicated exclusively to peripheral Benzodiazepine receptors and their natural and synthetic ligands. This work reviews the chemistry, biochemistry, and molecular biology of the pBR receptor and its ligands. It also provides a historical background, and pharmacological, biochemical and physiological aspects of research and therapeutic potential.
This volume will cover the historical background of the subject, together with the physiological, molecular biological and pharmacological aspects, with a discussion on the concept of sigma receptors subtypes and their postulated relevance for CNS disorders.
Advances in our understanding of the pathobiology of Alzheimer's disease, will lead to drugs aimed at prevention rather than cure. This book covers some of the most important of these advances. It also describes cell biological approaches that piece together the link between the genetic alterations and the phenotype we call Alzheimer's disease.
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