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This book examines the correlation of the coronavirus disease-19 [CE1] [AAS2] (COVID-19) infection with sleep, circadian rhythm, and sleep disorders. The chapters of the book explore sleep problems during the COVID-19 pandemic and its association with psychological distress and also review the prevalence of clinical cases of insomnia, anxiety, and depression in COVID-19 patients. The book further presents the correlation between sleep, circadian rhythms, and immunity that contributes toward more severe COVID-19. It summarizes the evidence on the interplay between circadian biology, sleep, and COVID-19. The chapters of the book discuss the relationship between obstructive sleep apnea (OSA) and adverse COVID-19 outcomes. Towards the end, the book presents studies on the anti-inflammatory, antioxidant, and immunotropic properties of melatonin and provides mechanistic insights into the potential therapeutic use of melatonin during the SARS-CoV-2 infection. The last chapter describes the publication output of sleep-related research during the pandemic and provides an overview and trends on sleep and covid-19 publication output. This book is an excellent source for neurologists, sleep specialists, and public health specialists.

This book delves into the multifaceted world of sleep apnea, presenting the latest advancements, challenges, and perspectives in the field. The book covers various topics, including neuro-stimulator use, positive airway pressure therapies, non-PAP and non-surgical treatments, surgical interventions, diagnosis and management of various sleep apnea phenotypes and comorbidities, and special populations such as pediatric and intensive care unit patients. The book discusses the pathophysiology and mechanisms underlying sleep apnea, examining the role of circulating miRNA as a potential biomarker for diagnosis. It also addresses the adverse health consequences associated with sleep apnea, including cardiovascular disease, diabetes, cancer, and hypertension. Furthermore, the book explores the application of telemedicine and wearable technologies in diagnosing and treating sleep apnea, as well as the impact of external factors such as the COVID-19 pandemic and traffic safety concerns related to sleep deprivation and sleep disorders. The book also highlights the importance of perioperative assessment and management of patients with sleep disorders, the role of REM sleep in sleep disorders, recent advances in sleep during pregnancy and postpartum, and the influence of sleep disturbances on hospitalized and intensive care unit patients. With contributions from experts in the field, this book offers valuable insights into the current state of sleep apnea research and practice, serving as a solid foundation for healthcare professionals, researchers, and students interested in understanding and addressing this prevalent sleep disorder. By providing a comprehensive overview of the field, this book aims to inspire further research and innovation in the diagnosis, treatment, and management of sleep apnea and related sleep disorders.