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This volume focuses exclusively on those endocytic processes that sequester proteins by a selective, receptor-mediated mechanism. The hallmarks of ,this process are the specific receptors, coated pits, coated vesicles and an ordered sequence of transit events leading to delivery to selected locations.

The cell surface is the barrier between the cell and its environment which regulates the flow of both simple and complex molecules into and out of the cell;

While emphasis is placed on neurotransmitter receptors in the mammalian central nervous system, the characteristics of these receptors in other species, both vertebrate and invertebrate, are also discussed where appropriate.

It is hardly necessary to define the concept of receptors to readers of this series, but it should be born in mind that in several instances receptors are undefined entities, whose molecular details remain to be established.

It is hardly necessary to define the concept of receptors to readers of this series, but it should be borne in mind that in several instances receptors are undefined entities, whose molecular details remain to be established.

Fifty-odd years have elapsed since the first observation of the response of visceral smooth muscle to an adenine nucleotide was reported by Drury and Szent Gyorgi (1929).

Bacteria adhere to and colonize almost any surface.

While emphasis is placed on neurotransmitter receptors in the mammalian central nervous system, the characteristics of these receptors in other species, both vertebrate and invertebrate, are also discussed where appropriate.