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This book is designed to provide a comprehensive and state-of-the-art resource for clinicians who care for patients with sepsis and research scientist alike, . Book sections have been structured to review the overall definitions and epidemiology of sepsis as well as current insights into the pathophysiology of sepsis.

This book is a guide to pharmacotherapy treatment of tobacco dependence. The 2020 American Thoracic Society clinical practice guidelines on treating tobacco dependence serves as the cornerstone for this work with its robust discussion of recommended treatment options and how to tailor treatment to specific patient populations. Tobacco dependence remains a major health concern for many adults and given the dramatic increase of youth electronic cigarette use, clinicians need a singular resource to treat these different populations. This book addresses that by following the three main points of how to best address the adverse impact of tobacco use on public health: 1) prevent initiation of tobacco use; 2) understand mechanisms of addiction; 3) effectively treat tobacco dependence.The book begins by describing the current patterns of product use, the adverse impact of tobacco on global health, and tobacco-related health disparities. Authors discuss both combustible andelectronic tobacco products, as well as current research on the adverse impact of vaping and associated flavorings including menthol, role of the e-cigarette in cessation, and treatment of adolescent nicotine dependence. Chapters conclude with a discussion of specific tobacco control policies to improve overall public health. This is an ideal guide for pulmonologists, pediatricians, primary care physicians and other specialty providers who see patients with nicotine dependence. This book is also of interest to public health professions to help inform public health campaigns and treatment offerings to reduce overall tobacco product use through prevention and treatment.

There are also comprehensive reviews on specific disease topics including chronic obstructive lung disease, lung cancer, atypical mycobacteria, interstitial lung disease, pulmonary hypertension, pulmonary embolism, obstructive sleep apnea, sleep disorders in older patients.

Chronic Obstructive Pulmonary Disease (COPD) is a major cause of morbidity and mortality worldwide.

Clinical research in critical care has exploded in the past several years and we now have a much better understanding of how to care for intensive care unit (ICU) patients in areas such as management of sepsis, fluid resuscitation, mechanical ventilation, antibiotic administration and sedation and analgesia.

Currently, there is no overview on the role of mitochondria in pulmonary diseases and this volume focuses on the mitochondrial metabolism, redox signaling, and mechanisms of mitochondrial pathways in lung injury, inflammation, repair and remodeling.

The origin of modern intensive care units (ICUs) has frequently been attributed to the widespread provision of mechanical ventilation within dedicated hospital areas during the 1952 Copenhagen polio epidemic.

Vitamin D and the Lung: Mechanisms and Disease Associations delivers a concise, evidence-based review of the evidence for a role of vitamin D in various lung disorders.

Pulmonary Sarcoidosis: A Guide for the Practicing Clinician is a valuable resource for clinicians of varied disciplines concerning the care of the sarcoidosis patient.

Alcohol Use Disorders and the Lung: A Clinical and Pathophysiological Approach is an excellent resource for clinicians who care for individuals affected by alcohol use disorders in diverse settings.

Gastroesophageal Reflux and the Lung provides a comprehensive review of current knowledge concerning normal deglutition and foregut digestive processes and examines how abnormalities of swallowing or excessive/abnormal GER can lead to respiratory tract dysfunction and lung disease.

Chronic Obstructive Pulmonary Disease (COPD) is a major cause of morbidity and mortality worldwide.

Vitamin D and the Lung: Mechanisms and Disease Associations delivers a concise, evidence-based review of the evidence for a role of vitamin D in various lung disorders.

This book serves as a unique, comprehensive resource for physicians and scientists training in pulmonary medicine and learning about pulmonary function testing.

This book serves as the primary reference for precision medicine in the fields of pulmonary, critical care and sleep medicine by documenting principles written by experts in several aspects of precision medicine.

This book serves as a unique, comprehensive resource for physicians and scientists training in pulmonary medicine and learning about pulmonary function testing.

This book provides an overview of pulmonary hypertensive diseases, the current understanding of their pathobiology, and a contemporary approach to diagnosis and treatment.

This book explores the non-interventional aspects ofinterventional pulmonology, focusing on diseases of the central airways.

Functional Respiratory Disorders: When Respiratory Symptoms Do Not Respond to Pulmonary Treatment is an important new book that will help clinicians consider the possible impact of functional contributions to the clinical presentation of every patient with respiratory symptoms and identified respiratory disease.

Functional Respiratory Disorders: When Respiratory Symptoms Do Not Respond to Pulmonary Treatment is an important new book that will help clinicians consider the possible impact of functional contributions to the clinical presentation of every patient with respiratory symptoms and identified respiratory disease.

This book is a comprehensive and authoritative source on nontuberculous mycobacterial (NTM) pathogens and diseases and their appropriate management, with a focus on lung disease.

This book explores the non-interventional aspects ofinterventional pulmonology, focusing on diseases of the central airways.

This book presents a systematic approach to the potential pulmonary complications of various systemic non-pulmonary pediatric disorders.

This book discusses normal sex-related differences in lung structure and function and the role these differences play in lung disease.

This book discusses health disparities in respiratory medicine and suggests methods to reduce them. Similarly, differences in health and health outcomes exist between differing socioeconomic groups, with lower income groups generally having poorer health and higher rates of chronic illness.

By providing a comprehensive overview of the current state of critical care ultrasonography, with content contributed by experts in the field, this text will serve as a valuable resource that will allow education in critical care ultrasound to keep pace with the rapid technological growth that has driven this vital area of critical care medicine.

This book provides a practical, stepwise, evidence-based approach to effective management of patients with difficult to treat asthma. Highlights include a comprehensive guide to management of severe asthma in children and pregnancy, as well as practical considerations to management of asthma based on different clinical phenotypes.

A Clinical Guide to Occupational and Environmental Lung Diseases delivers a concise compendium to the diagnosis and management of occupational and environmental lung diseases, incorporating evidence-based guidelines where available.

While chest radiography continues to serve as the primary tool for imaging the chest, advances in computed tomography (CT) have led to a variety of applications such as high-resolution CT (HRCT), advanced 3-D airway imaging, and image-guided procedures.The aim of this book is to deliver a clinically-oriented approach to pulmonary imaging.

Pediatric sleep-disordered breathing (SDB) has emerged as a prevalent problem in children. This unique, comprehensive and up-to-date review is the first full and critical review of the evidence on current therapeutic approaches to this clinical condition.