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Immunomodulatory agents have been expressed in defined tissues or throughout the body, providing tools for studying the functional consequences of dysregulated expression of biologi cal response modifiers.

The young investigator with an idea has to negotiate many institutional, federal, and industrial challenges in order to get a product to market.

They discussed the mechanism and regulation of motility, the metabolic strategy of human spermatozoa, the effects of exogenous fac tors such as antibodies, infections, and toxins, and finally the role of intracel lular calcium on sperm motility.

Cell Biology and Biotechnology: Novel Approaches to Increased Cellular Productivity contains the proceedings of the symposium by the same name held in Cambridge, Massachusetts, January 30 - February 2, 1992. Molecular Approaches Towards Manipulating the Expression of the Glucose Related Proteins in Mammalian Cells;

The proceedings review current knowledge and explores future research directions on the biologic changes of the hypothalamic-pituitary-ovarian axis across the menopausal transition and the associated changes in physiologic systems outside of the HPO axis, including the brain, the musculoskeletal and cardiovascular systems.

The aim of this symposium was to provide basic and clinical investigators with the latest information on the biology of wound healing and tissue repair. Written and edited by eminent experts in the field, the papers cover the general concepts of wound healing; the role of nutrients; endogenous growth factors; clinical applications of growth hormone and IGF-1 therapy; and clinical applications of peptide growth factors.

Therapeutic Outcome of Endocrine Disorders: Efficacy, Innovation and Quality of Life presents the proceedings of an international symposium held from November 13-16, 1997 in Palm Beach Gardens, Florida. The proceedings discuss scientific and clinical studies related to the treatment of endocrine disorders, including growth hormone deficiency, Turner Syndrome, constitutional delay of growth, treatment of diabetes, congenital adrenal hyperplasia, and congenital hypothyroidism.

This volume is the proceedings of the International Conference on Inhibin, Activin: Recent Advances and Future Views held in Tokushima, Japan from November 9-10, 1996. The Internationally recognized faculty present the latest research in the exploration of inhibin, activin and follistatin mechanisms of action.