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Includes information and images of clinical cases for infectious diseases including Avian Influenza; Listeriosis; Shiga toxin producing E coli; West Nile Virus; Hanta Virus; Malaria; Metapneumovirus; Dengue; Ebola; Staph aureus (community acquired) MRSA; Chikunguna; Bocavirus; HIV; Tickborne Bunyaviridae; Tickborne Flaviviridae; and, Yellow Fever.

Interventional cardiology has grown tremendously due to development of new devices and expansion of indications based on clinical trials. This issue provides a view of advanced techniques in the rapidly changing and growing field of interventional cardiology. It discusses topics such as emerging techniques for vulnerable plaque detection.

Examining Medical Complications in Pregnancy, this title offers reviews on topics including Preeclampsia, Chronic hypertension, Peripartum cardiomyopathy, Valvular heart disease in pregnancy, Pregestational diabetes, Asthma management, Management of renal disease, Renal transplant recipients and pregnancy, and Sickle disease and pregnancy.

Organized on a debate format, with experts in the field arguing the pros and cons of active controversies that challenge modern management of aortic disease, this book discusses genetic testing, use of biomarkers, optimal methods of brain protection in aortic arch surgery, and pre-enrollment echocardiogram to exclude aortic disease.

Offers information for the internist on diagnosis and treatment. This title covers such topics as insomnia, excessive sleepiness, REM behavior disorder, restless legs syndrome, obstructive sleep apnea, narcolepsy, pediatric sleep disorders, cognitive behavior therapy, and pharmacologic therapy.

Anemia is common among patients with heart failure. This title brings together the information about the relationship of anemia to heart failure and the role of anemia treatment in management of heart failure.

This issue of the Endocrinology and Metabolism Clinics, guest edited by Drs. Leonid Poretsky and Emilia Pauline Liao, will focus on Diabetes Mellitus: Associated Conditions. Articles in this issue include Metabolic syndrome; The role of glucocorticoids and insulin resistance in adipose tissue function and lipid metabolism; Cardiovascular disease; The Relationships between Cardiovascular Disease and Diabetes: Focus on Pathogenesis; Interventions for coronary artery disease; Peripheral Arterial Disease; Hypertension; Sleep apnea; Osteoporosis; Vitamin D deficiency; Diabetes and cancer; Dementia; Depression; and Polycystic Ovary Syndrome.

Includes topics such as: overview of cardiac markers in heart disease; methodologies for measurement of cardiac markers; natriuretic peptides in HF and ACS; tropoinins and high sensitivity troponins; point-of-care testing for cardiac markers; and ST-2 and galectin 3 in patients with heart failure.

Covers birthmarks of medical significance. This work offers reviews on topics including vascular birthmarks - introduction and classification, infantile hemangioma, other vascular tumors, coagulopathy associated with vascular tumors/Kassabach-Merrit Phenomenon, vascular malformations, genetics and syndromes, and epidermal nevi and nevus sebaceous.

Features such article topics as: Epidemiology of Osteoarthritis; Age-Related Changes in the Musculoskeletal System and the Development of Osteoarthritis; The Contribution of Osteoarthritis to Disability; Etiology and Assessment of Disability in Older Adults; and, Quality of Osteoarthritis Care for Community-Dwelling Older Adults.

Neuro-ophthalmology has been an established subspecialty in neurology. This title contains the following articles: Ocular Motor Cranial Neuropathy (Volpe); Papilledema (Wall); Transient Monocular Visual Loss (Ahmed/Foroozan); Multiple Sclerosis (Galetta); and Nonarteritic Anterior Ischemic Optic Neuropathy (Bonelli/Arnold).

Brings the practicing internist to the approaches in psychiatry. This title includes topics such as: collaborative care and consultation, including interviewing, cultural competence, and enhancing rapport; assessments of the risk of suicide or violence in a patient in crisis; cognitive impairment such as delirium and dementia; and more.

Provides cardiologists with practical information on prevention that can be easily applied to their patients. This title covers such topics as: diabetes, lipid-lowering therapy, RAAS blockade, emerging therapies for atherosclerosis prevention, and heart disease in women.

Highlights some of the exciting developments in pediatric oncology and hematology. This title includes three articles that focus on pediatric leukemia, which remains the most common form of pediatric cancer.

Provides information on the intersection between endocrinology and rheumatology, and explores rheumatologic manifestations of endocrine disease. This title covers topics such as: thyroid disease; parathyroid disease; diabetes mellitus; adrenal disorders; disorders of the pituitary gland; and pregnancy.

Supplies urologists with reviews devoted to the adult neurogenic bladder. This title also includes articles such as: Bladder Rehabilitation: Goals and Practice; Pharmacologic Therapy for the Neurogenic Bladder; Multiple Sclerosis and the Neurogenic Bladder; Spinal Cord/Brain Injury and the Neurogenic Bladder; and Botulinum Toxin Injections.

Addresses obstetric applications. This title includes articles such as U/S for Cervical length; Fetal ventriculomegaly; C/S scar ectopics; Skeletal dysplasias; Effects of obesity on obstetrical u/s imaging; Fetal lung; Abdominal wall defects; Fetal hydronephrosis; U/S for evaluation of fetal anemia; and Training for Ultrasound Guided Procedures.

Offers updates in trauma anesthesia. This title includes articles that includes best practices in video-assisted intubation devices, coagulation and hemorrhagic shock, homoestatis control, multiple casualties, massive bleeding and more.

Focuses on the topic of Neutropenia. In this title, articles include: Homeostasis and migration of neutrophil granulocytes, Granulocyte-colony Stimulating Factor (G-CSF) receptor signaling, New Granulocyte-colony Stimulating Factor (G-CSF) Receptor Signaling Pathways, Neutrophil elastase (ELANE) - Genetics and Pathophysiology, and more.

Osteoarthritis is the leading cause of disability among older adults affecting upward of 1 in 8 adults. This issue will cover epidemiology, imaging, disease management and modification, and many more topics.

Dr. Brown provides a timely upate on the clinical diagnosis and management of Hepatic Encephalopathy. His issue addresses current hot topics including Role of NH4 in Pathogenesis of Hepatic Encephalopathy; How to diagnose and manage HE in fulminant hepatic failure; New methods of Brain Imaging and testing (eg PET) and Hepatic Encephalopathy; Management New agents for HE (focus on NH4 lowering drugs used in UCD); Legal responsibility of MD when he diagnoses HE; Diets in Encephalopathy; and Neurological manifestations of HE.

In this issue the Guest Editors provide a contemporary look at the epidemiology, clinical manifestations, treatment and outcomes for neonatal-perinatal infections. Contributors include neonatologists, infectious disease, and critical care specialists with a wide variety of research interests in this arena. Readers will be exposed to the latest information on dosing of antibiotics, antivirals, and antifungals. This information is critical in the infant population given the rapid changes in physiology, metabolic pathways and renal elimination that occur over the first months of life. There is an extensive examination of infectious processes that commonly present in infants including meningitis, bloodstream infections, and urinary tract infections. Additional topics include infectious processes affecting the newborn (chorioamnionitis and TORCH infections) and premature infants (necrotizing enterocolitis). Specific pathogens are highlighted in articles on HSV, CMV/VZV, staphylococcal species, and Candida. Finally, the rationale for the most recent changes to guidelines for initiating therapy for early-onset neonatal sepsis are reviewed.

Presents the rheumatologist with the practices in quantitative assessment of common musculoskeletal conditions. This title covers topics that include quantitative measures of rheumatic diseases for clinical research versus standard clinical care; electronic and computer-generated patient questionnaires; the SDI and CDAI; and, DAS28.

Cancer is a life-threatening disease that requires a comprehensive approach, including health promotion, prevention, treatment, rehabilitation, and palliation. This title keeps primary care physicians informed about the developments in cancer treatment and prevention. It focuses on diagnosis, management of cancer survivors, and palliative care.

Includes articles on such topics as: screening for chromosomal abnormalities; cystic fibrosis screening; the role of second-trimester screening, in the post-first trimester screening era; modifying risk for Aneuploidy with second-trimester ultrasound after a positive serum screen; and, cost-effectiveness of Down syndrome screening paradigms.

This issue of Rheumatic Disease Clinics, guest edited by Drs. James Katz and Brian Walitt with the NIH, will cover several key aspects of diagnosing and treating Rheumatic Diseases in Older Adults. The Consulting Editor for the series is Dr. Michael Weisman. The topics discussed in the issue will include: Pharmacotherapy Pearls for the Geriatrician, Pathogenesis and Management of Sarcopenia, A Review of Osteoporosis in the Older Adult, Regional Rheumatic Disorders and Rehabilitation in Older Adults, Rheumatologic Manifestations of Malignancy, Sj├╢gren Syndrome and Other Causes of Sicca in Older Adults, Cardiovascular Disease Risk in Patients with Rheumatic Diseases, Update on Crystal-Induced Arthritides, Immune dysregulation in aging with a focus on B cells and their potential clinical consequence, and Spinal Stenosis, among others.

This issue of Anesthesiology Clinics, edited by Dr. Nabil Elkassabany and Dr. Edward Mariano, focuses on Regional Anesthesia, with topics including: Current evidence related to regional analgesia and hip surgery; Updates on billing and coding and establishing an acute pain service in private practice; Establishing a home catheter program for orthopedic surgery in pediatric patients or more broadly: updates on regional anesthesia for pediatric orthopedic surgery; Enhanced recovery after shoulder arthroplasty; Perioperative management of patient on opioid agonist antagonist therapy; Outcome metrics to be considered for regional anesthesia and acute pain medicine; Updates on multimodal analgesia (intransal ketorolac, IV acetmenophen, newer NSAIDS) for orthopedic surgery; Updates in enhanced recovery pathway for knee replacement versus updates outpatient knee replacement; Updates on new technology for regional anesthesia (peripheral nerve stimulators and cryotherapy); and Regional anesthesia and analgesia for the poly trauma patients.

This issue of Clinics in Chest Medicine, edited by Drs. Peter Marshall and Wassim Fares, focuses on Pulmonary Embolism, with topics including: Clinical Probability Tools for DVT, PE, & Bleeding; Prevention of DVTs and Pulmonary Emboli: General Measures and High-Risk Populations; Diagnosis of DVTs and PEs: New Imaging Tools and Modalities; Perfusion Defects Misdiagnosed as Pulmonary Emboli; The Vicious Cycle of Hypercoagulability and Pulmonary Hypertension; VTE in Special Populations; Preganncy and Thrombo-embolic Disease; Challenges and Changes to the Management of PE in the Emergency Department; The Value of Bedside Echocardiogram in the Setting of Acute & Chronic Pulmonary Embolism; Management of Low-Risk PE; Update on the ''Novel'' and Direct Oral Anticoagulants; Risk Stratification: Definitive/Aggressive Treatment of Hemodynamically Stable but Intermediate Risk Patients; Pulmonary Embolism Response Team (PERT); Surgical and Other Interventions for DVTs; IVC Filters; Catheter-Based Therapies of Pulmonary Emboli; Surgical-Based Therapies for PEs; and Chronic Thrombo-embolic Pulmonary Hypertension (CTEPH).

This issue of Sleep Medicine Clinics focuses on Sleep Disorders in Women''s Health, with topics including: Menstrual cycle effects on sleep; Impact of shiftwork on sleep, circadian rhythyms, and health in women; Sleep in pregnancy; RLS in pregnancy; Sleep-disordered breathing in pregnancy; Postpartum sleep and circadian rhythms; Chronic pain and autoimmune disorders in women; Management of sleep disturbance in women with cancer; Impact of stress and trauma on sleep; Sleep disorders in female veterans; Sleep and sleep disorders in the menopausal transition; and Impact of sleep disturbance on health and cognition in elderly women.