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This issue of Primary Care: Clinics in Office Practice, guest edited by Dr. Parvathi Perumareddi, is devoted to Nephrology. Articles in this issue include: Electrolyte Abnormalities, Pre-renal Azotemia, and Fluid Balance, Acute Kidney Injury, Chronic Kidney Disease and Chronic Renal Failure, Nephrotic Syndrome, Nephritic Syndrome (not urological), Renovascular Hypertension, Diabetic Nephropathy, Nephrolithiasis, Polycystic Kidney Disease, Renal Repercussions of Medications, Care of the Renal Transplant Patient, and more.

This issue of Anesthesiology Clinics, guest edited by Drs. Alison Perate and Vanessa Olbrecht, focuses on Pediatric Anesthesia. This is one of four issues each year selected by the series consulting editor, Dr. Lee Fleisher. Articles in this issue include, but are not limited to: The Pediatric Difficult Airway: Updates and Innovations; Current Knowledge of the Impact of Anesthetics on the Developing Brain; Anesthesia for Innovative Pediatric Surgical Procedures; Pediatric Mass Casualty Preparedness; The Pediatric Burn: Current Trends and Future Directions; Managing the Child with Complex Congenital Heart Disease; Modernizing Education of the Pediatric Anesthesiologist; Regional Anesthesia: Options for the Pediatric Patient; Managing the Pediatric Patient for Anesthesia Outside of the OR; New Trends in Fetal Anesthesia; Anesthetic Implications of the Common Congenital Anomalies; Managing the Adult Patient with Congenital Disease; Trends in Pain Management: Thinking Beyond Opioids; Sustainability in the OR: Reducing Our Impact on the Planet; Current Trends in OSA; and Processed EEG Guided Propofol Infusion in Children.

This issue of Clinics in Laboratory Medicine, guest edited by Dr. A. Zara Herskovits, will cover Laboratory Testing for Neurologic Disorders. This issue is one of four selected each year by our Editor-in-Chief, Dr. Milenko Jovan Tanasijevic. Topics discussed in this issue will include: molecular approach to diagnostic testing for children with developmental delay and congenital anomalies, proteopathic and seeding assays (such as RT-QUIC), genetic testing for ALS and FTD, Diagnostic and prognostic testing for Alzheimer''s disease, confounds in the interpretation of paraneoplastic antibody panels, Review of neurologic disease sendout testing at an academic medical center, development of new diagnostic tests for neurologic disorders, assuring quality in laboratory testing for sendout reference tests, diagnostic testing for patients with spinal muscular atrophy, among others.

This issue of Sleep Medicine Clinics, guest-edited by Drs. Amen Sergew and Lisa F. Wolfe, focuses on Noninvasive Ventilation and Sleep Medicine. This issue is one of four selected each year by series Consulting Editor, Dr. Teofilo Lee-Chiong. Articles include: Obesity hypoventilation - Traditional vs Non Traditional Populations; Spinal cord injury; Peri-Operative Care and Medication Related Hypoventilation; Lifetime Care of Duchenne Muscular Dystrophy; Management of Chronic Respiratory Failure in COPD - High and Low Intensity Ventilation; Management of Rare Causes Pediatric Chronic Respiratory Failure; Noninvasive Ventilator Management of ALS - Bulbar vs non Bulbar; Parsonage Turner; Noninvasive Ventilator Devices and Modes; Tailoring the Sleep Lab for Chronic Respiratory Failure; Long-Term Follow Up of Noninvasive Ventilation: Downloads and Troubleshooting; Extubating to Noninvasive Ventilation - NIV from ICU to Home; and From Tracheostomy to Noninvasive Ventilation - NIV from Long Term Acute Care to Home.

In collaboration with Consulting Editor, Dr. William Rayburn, Guest Editor Dr. Edward Chien has created a state-of-the-art monograph that focuses on Premature Rupture of Membranes. The issue separates articles into three sections: Prediction and Prevention, Interventions, and Special Topics, with articles on the following topics: Vaginal Microbiome; Cervical and Fetal Membrane Biomechanics; Management of the Short Cervix, Prolapsing Membranes, and Rescue Cerclage; Time to Deliver: Early - Late Preterm Management; Tocolysis; Use of Corticosteroids in Premature Rupture of Membranes; Antibiotics Prophylaxis for PPROM; Viral Infections (HIV, Hep B, Herpes, HCV); Antenatal Monitoring after PPROM; Periviable PROM; PPROM in Multiple Gestations and after Fetal Surgery; and Neonatal Issues after PPROM. Readers will come away with the current and clinical information they need to improve patient outcomes.

This issue of Interventional Cardiology Clinics, guest edited by Editor-in-Chief Matthew J. Price, will focus on Key Trials of the Decade. Trials discussed in this issue will include: Physiology over Angiography to determine lesion severity: The FAME trials; Percutaneous Coronary Intervention or surgery for multivessel disease: The SYNTAX trial at 10 years; Percutaneous Coronary Intervention or surgery for unprotected left main disease: The EXCEL trial at 5 years; Complete or Incomplete Revascularization for ST-Elevation Myocardial Infarction: the PRAMI trial and beyond; Abbreviated Dual Antiplatelet Therapy after PCI in High Bleeding Risk Patients: LEADERS-FREE and ONYX ONE; Transcatheter treatment of functional mitral regurgitation in patients with heart failure: The COAPT trial; Manual thrombectomy in Primary Percutaneous Coronary Intervention: Lessons learned from TOTAL; Paradigm shifts in the treatment of aortic stenosis: The PARTNER Trials experience; COURAGE and ORBITA in context: PCI for chronic stable CAD; SIMPLICITY to RADIANCE: Interpreting the past and mapping the future of renal denervation; From WOEST to AUGUSTUS: Dual Therapy after PCI; The ISCHEMIA Trial: Background, Design, Outcomes and Clinical Interpretation.

This issue of Cardiology Clinics will cover Coronary Artery Disease. Curated by Dr. Alberto Polimeni, this issue will explore topics in the field that are relevant for practicing clinicians. This issue is one of four selected each year by the series editorial board: Jamil A. Aboulhosn, David M. Shavelle, Terrence D. Welch, and Audrey H. Wu. The volume will include articles on: High sensitivity troponins in acute coronary syndromes, High bleeding risk patient with CAD, Complete revascularization in chronic coronary syndrome, Patient selection for protected PCI, Clinical applications of echo strain imaging in coronary artery disease, Mechanical circulatory support for cardiogenic shock, Impact of NO donors on atherogenesis and atherosclerosis progression, Non-invasive Imaging risk stratification for CAD, Antithrombotic therapy for patients with atrial fibrillation undergoing percutaneous coronary intervention, No-Reflow phenomenon, Coronary physiology assessment for the diagnosis and treatment of CAD, Bioresorbable coronary scaffold technologies, Non-coding RNAs in coronary artery disease, New advances in the treatment of severe coronary artery calcifications, and Refractory angina pectoris.

This issue of Immunology and Allergy Clinics, guest edited by Dr. Lanny Rosenwasser, will provide up-to-date clinical concepts regarding Biologics for the Treatments of Allergic Conditions. Articles in this outstanding issue include: Allergic Rhinitis/CRS/Polyposis, Eosinophilic Asthma, Pediatric Asthma, Severe Asthma, ACOS/COPD, Food Allergy, Atopic Dermatitis, Chronic Urticaria, Anaphylaxis, Drug Allergy, Cell Disorders, Biologics and Immunotherapy, and much more.

Together with Consulting Editor, Dr. Helen Bucher, Guest Editors Dr. Carlos Del Rio and Dr. Sandra Springer have put together an important monograph that addresses infections in IV drug users. They have selected top experts to contribute clinical reviews for infectious disease physicians. Articles are devoted to the following topics: Medical and Surgical management of Infectious endocarditis in persons who use drugs; The Microbiology Laboratory and the Opioid epidemic; The Geography of Infectious Diseases Related to the Opioid Epidemic; Soft tissue, bone and joint infections related to illicit drug use; Management of opioid use disorder and infectious disease in the inpatient setting; Outpatient antimicrobial and OUD management in persons who use drugs; Novel approaches to antimicrobials for injection drug use associated infections; HCV treatment and reinfection risk in persons who use drugs on medication treatment for OUD: A systematic review in CJS settings; Treating opioid use disorder and related infectious diseases in the criminal justice system; Harm reduction services to prevent and treat infectious disease in persons who use drugs; Improving the management of patients with chronic opioid therapy in the outpatient setting; The Global Task Force for Chronic Pain in People Living with HIV (PLWH): Developing a research agenda in an emerging field; and Lessons learned from the response to the HIV epidemic that can inform addressing the opioid epidemic. Readers will come away with the clinical information they need to treat and improve outcomes in these patients.

This issue of Medical Clinics, guest edited by Dr. Robert A. Smith and Dr. Kevin Oeffinger, is devoted to Cancer Screening and Prevention. Articles in this important issue cover the development of cancer screening guidelines, implementing cancer screening in the clinical setting, and screening for colorectal, lung, cervical, prostate, skin, and ovarian cancer.

This issue of Hematology/Oncology Clinics, Guest Edited by Dr. Raymond L. Comenzo, is devoted to Systemic Amyloidosis due to Monoclonal Immunoglobulins. This issue is one of six selected each year by our series Consulting Editors, George P. Canellos and Edward J. Benz. Topics discussed in this important issue include: The Spectrum of Monoclonal Immunoglobulin Diseases, Systemic Amyloidosis due to Clonal Plasma Cell Diseases, Systemic Amyloidosis due to Low-grade Lymphomas, The Process of Amyloid Formation due to Monoclonal Immunoglobulins, Cardiac Involvement, Renal Involvement, Liver and Gastrointestinal Involvement, Peripheral Nervous System Involvement, Options for Chemotherapy, Stem-cell Mobilization and Autologous Transplant, Monoclonal Antibody Therapies, Solid Organ Transplant, Supportive Care, Patient Voices, and Future Perspectives.

This issue of Rheumatic Disease Clinics, guest edited by Dr. Candace Feldman, will Health Disparities in Rheumatic Diseases. This issue is one of four selected each year by series Consulting Editor, Dr. Michael Weisman. Topics discussed in this issue include, but are not limited to: Disparities in Rheumatology Through the Lens of Critical Race Theory; Use of Quality Metrics to Identify Disparities in Lupus Care; The Role of Individual and Area-level Poverty on Lupus Disparities; Disparities in Lupus Care and Outcomes among U.S. Medicaid Beneficiaries; Disparities in Rheumatoid Arthritis Care; Disparities in Childhood-onset Lupus and Mental Health Care for Pediatric Lupus Patients; Disparities in Rheumatic Disease Care, Access and Outcomes in the First Nations Population; Impact of Psychosocial Factors on RA and Lupus Health Disparities; Racial and gender disparities among patients with Gout; Racial/ethnic and geographic disparities in knee and hip osteoarthritis; Racial/ethnic Disparities in Osteoarthritis Management; Racial disparities in systemic sclerosis; Community-engaged Research: Lupus Conversations; Leveraging Telemedicine as an Approach to Address Rheumatic Disease Health Disparities; Understanding the Role and Challenges of Patient Preferences in Disparities in Rheumatic Disease Care; Designing an Intervention to Improve Management and Care Coordination for High Risk Lupus Patients; Greatest Challenges and Strategies to Achieve Equitable Rheumatologic Care Across the World, among others.

This issue of Emergency Medicine Clinics, guest edited by Drs. Michael C. Bond and Arun Sayal, focuses on Orthopedic Emergencies. This is one of four issues each year selected by the series consulting editor, Dr. Amal Mattu. Articles in this issue include, but are not limited to: Emergency Medicine Orthopedic Assessment: Pearls/Pitfalls; Emergency Orthogeriatrics: Concepts and Therapeutic Considerations for the Elderly Patient; Pediatric Orthopedic Emergencies; The Emergent Evaluation and Treatment of Hand and Wrist Injuries; The Emergent Evaluation and Treatment of Elbow and Forearm Injuries; The Emergent Evaluation and Treatment of Shoulder, Clavicle and Humerus Injuries; The Emergent Evaluation and Treatment of Pelvic, Hip and Femur Injuries; The Emergent Evaluation and Treatment of Knee and Leg Injuries; The Emergent Evaluation and Treatment of Ankle and Foot injuries; The Emergent Evaluation and Treatment of Neck and Back Pain; Risk Management and Avoiding Legal Pitfalls in the Emergency Treatment of High-Risk Orthopaedic Injuries; Sports Medicine Update: Mild Traumatic Head Injury; Pain Management for Orthopaedic Injuries; and Ultrasound Imaging in Orthopaedic Injuries.

In consultation with Consulting Editor, Dr. Charles Lightdale, Dr. Kenneth Chang has assembled top authors to provide a current update on the management of GERD. Clinical review articles provide updates on the these important topics: Mechanism and Pathophysiology of GERD; Personalized Approach in the work-up and management of GERD; Proton Pump Inhibitors; Radiofrequency Treatment for GERD; Trans-oral Incisionless Fundoplication (TIF); Innovations in Endoscopic Therapy for GERD; Laparoscopic Hernia Repair and Fundoplication, Failed Nissen; Laparoscopic Sphincter Augmentation (LINX); Refractory GERD and Functional Heartburn; and Extra-esophageal GERD and LPR. Readers will come away with the latest techniques and clinical applications to improve patient outcomes.

This issue of Heart Failure Clinics, guest edited by Giovanni Esposito and Michinari Hieda, will cover key topics in Cardiovascular Emergencies. This is part two of a two-part issue and is one of four issues selected each year by our series consulting editor, Dr. Eduardo Bossone. Topics discussed in this issue will include: Case Report in the ER, Cardiac Energetics in Patients with Acute Myocardial Infarction, Cardiac Emergency in Patients with Left Ventricular Assist Devices or Heart Transplantation, Cardiac Emergency in Patients just before Going to Left Ventricular Assist Device, Cardiac Emergency in Patients with Left Ventricular Assist Devices, Acute Aortic Syndrome, Multimodality Imaging in Cardiovascular Emergencies, Biomarkers in the Emergency Room, Acute Pulmonary Embolism, and Obesity Patient with Heart Failure.

Approx.240 pages

This issue of Emergency Medicine Clinics, guest edited by Mike Winters and Susan R. Wilcox, focuses on Emergency Department Resuscitation. This issue is one of four selected each year by series Consulting Editor, Dr. Amal Mattu. Topics include: Mindset of the Resuscitationist; Updates in Cardiac Arrest Resuscitation; Post-Arrest Interventions That Save Lives; Current Concepts and Controversies in Fluid Resuscitation; Emergency Transfusions; Updates in Sepsis Resuscitation; Pediatric Cardiac Arrest Resuscitation; The Crashing Toxicology Patient; The Crashing Obese Patient; Massive GI Hemorrhage; Updates in Traumatic Cardiac Arrest; Resuscitating the Crashing Pregnant Patient; Pearls & Pitfalls in the Crashing Geriatric Patient; Current Controversies in Caring for the Critically Ill PE Patient; and ECMO in the ED.

Suitable for the internist, this title covers various approaches to drug hypersensitivity. It also explores complex clinical pictures, including the side effects to biologics, anticoagulation (including HIT), and cytostatic drugs (such asoxaliplatin, cisplatin, paclitaxel, and others).

Discusses various aspects of diagnosis and treatment of inflammatory bowel disease. This book places emphasis on comparing treatment paradigms, current and future biologics agents, safety profile of therapeutics, and novel diagnostic and prognostic tools for IBD.

Discusses topics such as ocular ultrasound, basic procedures, musculoskeletal, deep vein thrombosis, advanced procedures, and OB/GYN.

Examines co-morbidities in patients with heart failure. This book includes topics such as hypertension, diabetes, pulmonary disorders, cardiorenal syndrome, anemia, depression, atrial fibrillation, obesity and cardiac cachexia, peripheral vascular disease, rheumatologic disorders, co-morbidities and polypharmacy, and coronary artery disease.

This issue of Clinics in Geriatric Medicine is centered on the management of the geriatric fragility fracture patient. This issue features expert clinical reviews on topics such as Principles of comanagement, Lean business model and implementation of a Geriatric Fracture Center, Preoperative optimization and risk assessment, Preoperative reversal and management of anticoagulation and antiplatelet agents, Classification and surgical approach to hip fractures for non-surgeons, Special anesthetic consideration for the fragility fracture patient, Non-surgical management and palliation of fragility fractures, and Management of post-operative complications including Delerium, Anemia, Venous thromboembolism, and Cardiovascular disease and volume management. Also included are articles on Transitions in care and rehabilitation, Osteoporosis related secondary fracture prevention, Post-operative assessment of falls risk and prevention, and Fragility fractures requiring special consideration.

Gout is now the most common form of inflammatory arthritis in the United States, with a recent resurgence of research interest in its cause and management. Calcium crystal-related arthritis has also attracted renewed attention, with new nomenclature having been recently elaborated, aiding contemporary research efforts. This topic has never been covered in Rheumatic Disease Clinics and it represents a large content hole. The articles will cover diagnosis, management, emerging therapies and imaging.

Dr. Herrera has created an issue that will serve as a complete update on the topic of Portal Hpertension. Content is provided from medical therapies to surgery on the patient with portal hypertension. The following important issues are addressed: Invasive and Noninvasive Methods of Measuring Portal Pressure; Primary Prophylaxis of Varceal Bleeding; Gastric and Ectopic Varices; Hepatic Hydrothorax; and Hepatopulmonary Syndrome. Readers will come away with state-of-the-art information on the topic of portal hypertension.

Experts from childrens'' hospitals across the United States discuss diagnosis, treatment, and pathophysiology of head and neck masses in children. Topics include: Branchial cleft cysts; Thyroglossal duct cyst and ectopic thyroid; Vascular malformations; Thyroid nodule and malignancy in children; Lymphoma in pediatrics; Malignancies in the pediatric head and neck - rhabdomyosarcoma and neuroblastoma; Skull base and more including intranasal masses; Tumors of the maxsilla and mandible; Teratoma and dermoid cysts; Inflammatory adenopathy; Disorders and tumors of the salivary glands; Intraoral and lingual lesions; and the Exit procedure. Beyond relevance to Otolaryngologists, this issue of Otolaryngologic Clinics is appropriate for cancer specialists, pediatricians, family practitioners, general surgeons, and pediatric nurse practitioners. Residents training in those fields, as well as Neurosurgery and Ophthalmology, will find this practical.

This issue of Hematology/Oncology Clinics of North America, guest edited by Drs. Bipin Savani and Mohamad Mohty, is devoted to Bone Marrow Transplantation. Articles in this issue include: Acute Myeloid Leukemia (AML); Acute Lymphoid Leukemia (ALL); Myelodysplastic Syndrome (AML); Myeloproliferative disorders (MPD); Chronic Lymphoid Leukemia; Chronic Myeloid Leukemia (CML); Multiple Myeloma and Amyloidosis; Non-Hodgkin Lymphoma (NHL); Hodgkin Lymphoma (HL); Severe Aplastic Anemia (SAA) and Paroxysmal Nocturnal Hemoglobinuria (PNH); Sickle Cell Anemia; Thalassemia; Benign immunodeficiency diseases; and Referral to transplant centers.