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In consultation with Consulting Editor, Dr. Lucky Jain, Drs. Jonathan M. Davis and Errol R. Norwitz have put together a state-of the-art issue of the Clinics in Perinatology devoted to Perinatal Pharmacology. Clinical review articles are specifically devoted to the following:  Drugs for the prevention and treatment of preterm labor; Drugs for the prevention and treatment of hypertensive disorders of pregnancy; Drugs to promote neuroprotection; Medications that cause fetal anomalies and possible prevention strategies; Safety and efficacy of psychotropic medications during pregnancy; Treatment of viral infections during pregnancy (HIV, herpes, CMV, hepatitis C); Drugs to control diabetes during pregnancy; Cardiotonic drugs; Drugs to treat coagulation disorders in the newborn; Drugs for the prevention and treatment of bronchopulmonary dysplasia;  Drugs for the prevention and treatment of neonatal brain injury; Drugs for the prevention and treatment of sepsis in the newborn; Analgesia, opioids and other drug use during pregnancy and Neonatal Abstinence Syndrome; Medications and breast feeding; Principles of pharmacokinetics in the pregnant woman and fetus; and Challenges in designing clinical trials to test new drugs in the pregnant woman and fetus. Readers will come away with the latest information on therapeutics as they seek to utilize evidence-based recommendations to improve patient outcomes.

In consultation with Consulting Editor, Dr. Lucky Jain, Drs. Maximo Vento and Waldemar Carlo have put together a state-of the-art issue of the Clinics in Perinatology devoted to Perinatal Pharmacology. Clinical review articles are specifically devoted to the following: Monitoring and assessment of oxygenation in infants; Oxygen toxicity in neonates; New methods for non-invasive oxygen administration; Targeting oxygen in preterm and term infants starting at birth; Newborn resuscitation in settings without access to supplemental oxygen; Noninvasive versus invasive ventilatory support; Nasal SIMV versus Nasal CPAP before and after invasive ventilatory support; Is high-flow cannula inferior to CPAP for neonates?; Intermittent hypoxia: Importance; Closed-loop control of inspired oxygen in neonates: Compliance with targets; Meta-analysis oxygenation saturation targeting trials: Do infant subgroups matter?; Targets of oxygen saturation to optimize eye outcomes; Achieved oxygenation saturations and outcome in extremely preterm infants; Pulmonary hypertension in preterm infants; and Current recommendations and practice of oxygen therapy in preterm infants. Readers will come away with the latest information on oxygen therapy as they seek to utilize evidence-based recommendations to improve patient outcomes.

Physical medicine and rehabilitation (PM&R) physicians across the country see injured runners every day. Running injuries may impact other areas of the body and PM&R physicians are trained to treat the body as a whole, as opposed to treating just the injury, they work to identify the true source of the problem and develop a training or rehabilitation program to solve it.

This issue of Orthopedic Clinics will focus on the most common complications that arise in orthopedic surgery. Articles to be included will cover pediatrics, trauma, upper extremity, adult reconstruction, and foot and ankle.

Nerve-related injuries of the lower extremity are frequently encountered in orthopaedic practice. Proper and timely diagnosis and treatment are the keys to optimizing outcomes. This issue will include articles on: Introduction to Peripheral Nerve Diagnostics, Epidermal Nerve Fiber Density Biopsy, Lower Extremity Focused Neurological Examination, Metabolic Nerve Entrapment, Lower Extremity Compartment Syndromes, Treatment of Recurrent Morton's Neuroma, Proximal Tibial Nerve Entrapment and Treatment, and many more exciting articles!

The world of sports medicine faces unique medical ethics issues. In this issue articles will include: Fundamental Ethical Principles in Sports Medicine, Confidentiality in Sports Medicine, Informed Consent in Sports Medicine, Conflicts of Interest in Sports Medicine, Performance enhancing drugs in sports medicine, Gene doping in sports medicine, Ethical considerations for analgesic use in sports medicine, and many more!

This issue will include articles on Supramalleolar osteotomies for posttraumatic malalignment of the distal tibia, Intra-articular osteotomies for malunited tibial pilon fractures, Secondary reconstruction for malunions and nonunions of the talar body, Corrective osteotomies for malunited tongue type calcaneal fractures, Joint-sparing corrections of malunited Chopart joint injuries and many more!

This issue of Orthopedic Clinics will focus on orthopedic urgencies and emergencies. Articles to be included will cover pediatrics, trauma, upper extremity, adult reconstrucion, and foot and ankle.

This issue of Clinics in Podiatric Medicine and Surgery will focus on the dermatologic manifestations of the lower extremity. Articles will include: Fungal, Nail Surgery, Psoriasis, Eczema, Drug Reactions, Melanoma, and many more.

This issue of Clinics in Sports Medicine will focus on hip arthroscopy; specifically, imaging, injections, labrum, cartilage, capsule, cam and many more exciting articles.

CDC estimates reveal that 1.6 million to 3.8 million concussions occur each year. This issue will include topics such as pathophysiology, imagine, rturn to learn programs and long-term consequences of concussions.

Focuses on the restoration of ambulation in adults suffering from central neurologic disorders, which is a major area for physiatrists. This title includes articles such as MS, stroke, Parkinson's disease, and spinal cord injuries.

This issue of Hand Clinics will include articles on tendon transfers in the upper limb such as: Principles of Tendon Transfers, Biomechanics of tendon transfers, Restoration of Shoulder Function, Restoration of Elbow Flexion, Radial Nerve Tendon Transfers, High Median Nerve Tendon Transfers, Low Median Nerve Transfers (Opponensplasty), Ulnar Nerve Tendon Tendon Transfers for Grasp (Intrinsics), and many more!

This issue of Fooot and Ankle Clinics will focus on Injectable rh-PDGF in collagen carrier for hindfoot fusion; Vancouver experience of rh-PDGF; B2-A polypeptide in foot ankle fusion; Adipose-derived msc in hindfoot fusion; Polyvinyl for hallux rigidis; New development of novel hammer toe and mt plate; Large BM Intra articular allograft; and many other articles surrounding bone grafts, bone graft substitutes, and biologics.

This issue will include: Percuataneous Surgery for mild to moderate hallux valgus, percuataneous surgery for severe hallux valgus, technique and outcomes of chevron and basal osteotomies, percutaneous metatarsalgia and lesser toe surgery, distal minimally invasive metatarsal ostetomies and lesser toe correction, and many more exciting articles.

This issue of Orthopedic Clinics will focus on sports-related injuries. Articles to be included will cover pediatrics, trauma, upper extremity, adult reconstrucion, and foot and ankle.

Foot and ankle arthroscopy involves the surgical evaluation and treatment of the foot and ankle for a variety of conditions. This issue will cover everything from Arthroscopic Anatomy, Arthroscopic Instrumentation, Imaging Aspects of Joint Pathology and Arthroscopic Techniques, Intra-articular Soft Tissue Pathology, to Subtalar Joint Arthroscopy, and many more exciting articles.

The decision process for determining when to return an injured or ill athlete to practice or competition includes many factors. This issue will cover Return to Play Following Cervical Disc Surgery; Return to Play Following Anterior Shoulder Dislocation and Stabilization Surgery; Return to Play Following Shoulder Surgery in Throwers; Return to Play Following Ulnar Collateral Ligament Reconstruction; Return to Play Following Hand and Wrist Fractures; and many more articles on returning to play post  musculoskeletal injuries.

Mutilated hand injuries are one of the most challenging reconstruction problems than can confront hand surgeons. This issue will cover outcome and functional measurement in mutilating hand injuries; skin coverage considerations in a mutilating hand injury; reconstruction of major degloving injuries of the hand; challenges posed by delayed presentation of mutilating hand injuries; and many more articles surrounding this topic.

This issue of Physical Medicine and Rehabilitation Clinics of North America will cover regenerative medicine. Rapid advances in stem cell science are opening new avenues for drug discovery and may lead to new uses of stem cells for other musculoskeletal disorders. Artcles to be included are: Evidence-Based Regenerative Prolotherapy and Perineural Injection Approaches; Platelet Rich Plasma; Autologous Conditioned Serum; Stem Cell Considerations for the Clinician; Adipose Derived Stromal Vascular Faction and Stem Cell Use, as well as many others.

This issue of Foot and Ankle Clinics will focus on controveries and will include topics such as: Arthrodesis vs. ORIF for lisfranc injuries; What is the role for percutaneous treatment of Lisfranc injuries; Syndesmosis fixation- screws vs. flexible fixation; Management of late syndesmosis issues; Small incision vs. extensile lateral for calc fractures; and many more!

This issue of Hand Clinics will include the following articles: Management of Acute Adult Hand Burns; Management of Acute Pediatric Hand Burns; Electrical Injury; Frostbite Injury; The Biologic Principles of Scar and Contracture; Postburn Contractures of the Hand; Biology and Treatment of Upper Extremity Heterotopic Ossificatio; Postburn Contractures of the Elbow and Heterotopic Ossification; Reconstruction of the Adult and Pediatric Burned Hand; Microsurgical Reconstruction of the Burned Hand; The Use of Dermal Skin Substitutes for the Treatment of the Burned Hand; and many more exciting articles!

This issue of Clinics in Podiatric Medicine and Surgery will cover the diabetic charcot foot and how to manage it with a team approach. Articles will include: The Diabetic Charcot Foot from 1936 to 2016: Eighty Years Later and Still Growing; Pathogenesis and Classification Systems for the Diabetic Charcot Foot; An Overview of Medical Imaging for the Diabetic Charcot Foot; Pharmacological and Conservative Treatments for the Diabetic Charcot Foot; An Overview of Internal and External Fixation Methods for the Diabetic Charcot Foot and Ankle; Surgical Treatment Options for the Diabetic Charcot Midfoot Deformity; and many more.

ACL reconstruction remains one of the most common orthopedic procedures performed today. This issue will discuss controversies that can arise. Articles to be included are: Diagnosis of ACL Injury: Epidemiology, mechanism of injury patterns, history, PE, and ancillary test findings including x-ray and MRI; Anatomy of the ACL: Gross, arthroscopic, and Radiographic as a basis of ACL surgery; Graft selection in ACL surgery: Who gets what and why; Management of the ACL injured knee in the skeletally immature athlete; Indications for Two-incision (outside in) ACL Surgery and many more exciting articles!

This issue will focus on traumatic brain injury and will include articles on the following: Pathophysiology of TBI; Acute Management of Moderate-Severe TBI; Disorder of Consciousness; Rehabilitation of Moderate-Severe TBI; Acute Diagnosis and Management of Concussion; Rehabilitation of Persistent Symptoms after Concussion Chronic Traumatic Encephalopathy; Unique Aspect of TBI in the Military and Veteran; and many more!

This issue focuses on Pelvic Pain. Article topics include: Pelvic Pain-an overview; Anatomy and Physiology of the Pelvic Floor; Office Examination of Neuromuscular Pelvic Pain; Diagnostic Studies for Neuromuscular Pelvic Pain; Pelvic Floor Myofascial Pain and Associated Disorders; Bony and Ligamentous Causes of Pelvic Pain; Coccydynia;Neurogenic Pelvic Pain; Urologic and Gynecologic Sources of Pelvic Pain; Physical Therapy for the Treatment of Pelvic Pain; and more!

This issue of Orthopedic Clinics focuses on Orthobiologics. Article topics include: Does Prior Cartilage Restoration Impact Outcomes Following Knee Arthroplasty?; Clinical Applications of Tissue Engineering in Joint Arthroplasty: Current Concepts Update; Usage of Bone Graft Substitutes; Bone morphogenetic protein; Role of Bone Marrow Aspirate in Orthopaedic Trauma; Orthobiologics in Pediatric Sports Medicine, and more!

This issue of Clinics in Podiatric Medicine and Surgery focuses on Foot and Ankle Arthrodesis. Article topics include: Lesser Toe Arthrodesis; First Metatarsophalangeal Arthrodesis; Tarsometatarsal Arthrodesis for Lisfranc's Injuries;Subtalar Joint Arthrodesis for Elective and Post-Traumatic Foot and Ankle Deformity; Midfoot and Hindfoot Arthrodesis for Elective and Post-Traumatic Foot and Ankle Deformity; Internal and/or External Fixation for Ankle Arthrodesis; Tibiotalocalcaneal Arthrodesis; Management of Osteomyelitis, Bone Loss and Arthrodesis in the Diabetic Charcot Foot and Ankle; Free Flap Coverage for Revisional Foot and Ankle Procedures; andCurrent Orthobiologics for Elective Arthrodesis and Nonunions of the Foot and Ankle.

This issue of Clinics in Sports Medicine, edited by Eric McCarty, will cover a variety of useful topics related to Articular Cartilage. Articles include, but are not limited to: Basic science of articular cartilage; Non-operative options for management of articular cartilage disease; Biologic options for articular cartilage wear; Management of OCD lesions of the Knee; Elbow and Ankle, Microfracture; Osteochondral Autograft; Allografts; Autologous Chondrocytes and Next Generation Matrix based Autologous Chondrocyte Implantation; Management and surgical options for articular defects in the shoulder; and Management and surgical options for articular defects in the hip, among others.