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Polymer-Drug Conjugates: Linker Chemistry, Protocols and Applications discusses important concepts, fundamentals and prospective applications of 'Linker Chemistry' in a clear-and-concise manner. The book provides vital information on chemical entities binding with the drug-polymer complex for targeted drug delivery systems. It highlights roles and significance, different classes and synthetic protocols as well as mechanisms of chemical bond formation in drug-polymer conjugation in drug delivery, also offering insights into the mechanism of polymer interaction with linker and drug molecules by biodegradable chemical bonding. The protocol of binding with drug molecules is clearly explained and justified with case studies, helping researchers and advanced students in the pharmaceutical sciences understand fundamentals involved and related aspects in molecule designing for effective therapeutic benefits.
Probiotics is a broad term used for friendly bacteria, more appropriately defined as live microorganisms, which when administered in adequate amounts confer a health benefit on the host. These are increasingly used as food as well as pharmaceuticals due to their wide range of health benefits accompanied with low cost and negligible side effects. The tremendous growth of probiotic products in the global market has necessitated encountering formidable challenges posed due to lack of appropriate regulatory standards. For acceptance of probiotics based products with uniform quality, greater safety of patients, with established scientific evidences for holistic therapeutic benefits in treatment of various ailments, drafting of comprehensive regulatory guidelines is the need of the hour. The proposed work is to take lead in current international scenario by framing a comprehensive and harmonized guideline to be accepted universally.
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