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Flow of ions through voltage gatedchannels can be represented theoretically using stochastic differentialequations where the gating mechanism is represented by a Markov model. The flow through achannel can be manipulated using various drugs, and the effect of a given drugcan be reflected bychanging the Markov model.

The computational approach to understanding nature and technology is currently flowering in many fields such as physics, geophysics, astrophysics, chemistry, biology, and most engineering disciplines. It is our goal to teach principles and ideas that carry over from field to field.