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This textbook for undergraduate and postgraduate students discusses advancements in forensic DNA analysis since early texts were published. It presents conventional and latest serological and molecular biological methods for body fluid identification. This book also describes the applications and advantages of next-generation sequencing (NGS) compared to conventional methods in forensic DNA analysis. It also defines the growing importance, techniques, and applications for the analysis of non-human DNA in forensic sciences. Further, the book examines the role of DNA databases in forensic interpretation and criminal investigations. Towards the end, this textbook reviews the application of forensic DNA technology in analyzing real-time casework samples and presents the guidelines, ethical issues, and other challenges of forensic DNA analysis. This textbook is an essential resource for students and practitioners interested in gaining knowledge of up-to-date forensic techniques and theirapplications in forensic DNA analysis.
This reference book comprehensively reviews the significance of DNA technology in forensic science. After presenting the theory, basic principles, tools and techniques that are used in forensic DNA typing, it summarizes various techniques, including autosomal STR, Y-STR, X-STR, mitochondrial DNA and NGS, used in solving both criminal as and civil cases, such as paternity disputes, identification of mutilated remains, and culprit identification in sexual assault and murder cases. It also provides an overview of DNA-based genetic diagnostics for various diseases, and discusses the role of DNA typing in drug reactions, as well as the application of non-human DNA profiling of animals and plants in forensic science investigations. Lastly, the book examines the role of internal quality control in maintaining the high quality of DNA profiling.
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