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Drug Delivery: Advances and Emerging Strategies is an advanced reference for researchers and students in pharmaceutical science, materials sciences and biomedical engineering exploring ways to deliver drug effectively to specific systems and organs in the human body. Each chapter covers the particular challenges provided by membranes, the environment, and the involved organ physiology and how emerging strategies and recent advances are helping overcome them. The opening chapter provides an overview of drug delivery, setting the stage to the remaining chapters of the book. Next come oral, pulmonary, vaginal, ocular and nasal dedicated chapters. The following chapters cover colonic, transdermal and transungual, brain and nose-to-brain delivery. The next chapters focus on vaccine delivery, and then organ specific chapters to the myocardium, kidney, liver, pancreas, buccal and sublingual, closing with injectable drug delivery systems. "Drug Delivery: Advances and Emerging Strategies" offers an integrated and up-to-date overview of drug delivery methods, technologies and approaches targeting body systems and organs. Researchers in pharmaceutical science will benefit from the consolidated outlook provided. Advanced students in related areas will benefit from the introduction and discussion around barriers, physiology and how to overcome them to transport drug molecules to the target.
Microneedles explores the design, fabrication and use of microneedles for drug and vaccine delivery. This book discusses the contemporary status of the field, describing several areas in detail, including the distinct types of microneedles (dissolving, solid, coted, hollow and hydrogel-forming). The anatomy of the eye is also described to facilitate an understanding of microneedle-assisted ocular drug delivery. Finally, the book provides a detailed discussion of microneedle use in the field of diagnostics, with a chapter dedicated to the mathematical modeling of microneedle-mediated drug delivery. As microneedles can be used by research scientists in academia and in industry, this book will be ideal for regulatory scientists and graduate students who find the topic relevant to their area of study. Provides information for the design and fabrication of microneedles Discusses choice of materials, fabrication protocol, sterilization protocol and characterization Supplies the most up-to-date research on all aspects of microneedles
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