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Increased morbidity leads to longer hospital stays, higher hospital expenditures, chemotherapy delays, and a lower standard of living. Several biochemical markers, such as the neutrophil-lymphocyte ratio (NLR) and platelet lymphocyte ratio (PLR), have historically been used to determine the extent and impact of an inflammatory reaction. Low preoperative PLR was revealed as an independent risk factor for postoperative problems. A lower PLR also indicates a lower TLC (compromised cell-mediated immunity and malnutrition) as well as a higher platelet count (inflammation and high thrombophilic diathesis). The neutrophil-to-lymphocyte ratio (NLR) is a biomarker that reviews the balance between two elements of the immune system: acute and chronic infection (as indicated by the neutrophil count) and adaptive immunity
After surgery, complications are usual. While significant problems following major abdominal surgery are commonly estimated to be approximately 25%, the frequency of any postoperative unwanted outcome following major abdominal surgery has been estimated to be as high as 50%¿60%. Despite modern surgical methods and preventive perioperative medication, surgery stimulates an immediate inflammatory process over a stress reaction, and some major consequences such as surgical site infection, sepsis, and multiple organ failure may emerge in the early postoperative period. The neutrophil/lymphocyte ratio (NLR) and the platelet/lymphocyte ratio (PLR) are two inexpensive, repeatable, and quantitative indicators of systemic inflammation.
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