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This issue of Otolaryngologic Clinics of North America, devoted to Parotid Disease, is guest edited by Drs. Babak Azizzadeh and Babak Larian. Articles in this outstanding issue include: Parotid Gland and Facial Nerve Anatomy; Parotid Gland Imaging; Evaluation of Parotid Lesions; Benign Parotid Tumors and Management; Diagnosis and Management of Malignant Salivary Gland Tumors of the Parotid Gland; Parotitis and Sialoendoscopy of the Parotid Gland; Parotidectomy for Benign Parotid Tumors; Parotidectomy for Parotid Cancer; Parotid Tumors and the Facial Nerve; Loco-Regional Parotid Reconstruction; Free Tissue Transfer in Parotid Reconstruction; Facial Paralysis Reconstruction; Periocular Reconstruction in Patients with Facial Paralysis; Rare Parotid Diseases; and Management of Frey's Syndrome.