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Since the emergence of 2022's monkeypox virus (MPXV) outbreak, it has been the heading of news and research articles that MPXV is being involving non-endemic areas after about its 80-year presence in endemic areas. Efforts are concentrated on understanding how MPXV has evolved to cause an epidemic. The book provides a comprehensive compendium of chapters on poxviruses in different domains. It concludes that the main problem we should deal with is not to address how MPXV has overcome the distance between non-endemic and endemic areas, but it is the non-cooperativity of logistics, research, and science in managing poxviruses' outbreaks.
Gastrointestinal cancers are among the most prevalent malignancies worldwide, with high rate of global cancer incidence and cancer-related death. Gastrointestinal cancers include esophageal cancer, gastric cancer, colorectal cancer, pancreatic cancer, and liver cancer, which all, except the last one, are covered in this volume. The fourth volume of the ¿Interdisciplinary Cancer Research¿ series, entitled ¿Gastrointestinal Cancers: An Interdisciplinary Approach¿ publishes comprehensive volumes on mechanisms of gastrointestinal cancers and novel immunotherapy opportunities and presents the most updated and peer-reviewed chapters on gastrointestinal cancers therapy. This interdisciplinary series is of special value to researchers working on cell biology, immunology, biochemistry, genetics, and practitioners working on oncology and gastroenterology. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value for researchers, oncologists, and gastroenterologists who wish to extend their knowledge on gastrointestinal cancers.
Cancer treatment is a challenging issue, while the treatment modalities have extended from traditional surgery, chemotherapy, and radiation therapy to new therapeutic approaches, including targeted therapy, immunotherapy, stem cell transplantation, and hormone therapy. Therefore, an interdisciplinary approach is needed to find a better therapeutic protocols in order to increase the prognosis and quality of life of patients with cancer.The second volume of the ¿Interdisciplinary Cancer Research¿ series, entitled ¿Cancer Treatment: An Interdisciplinary Approach¿ publishes comprehensive volumes on different cancer treatment modalities and presents the most updated and peer-reviewed articles on cancer therapy. This interdisciplinary series is of special value to researchers and practitioners working on cell biology, immunology, hematology, biochemistry, genetics, oncology and related fields. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value for researchers and clinicians who wish to extend their knowledge on cancer treatment.
This contributed volume book aims at discussing transdisciplinary approaches to address common problems. By working transdisciplinarily, researchers coming from different disciplines can work jointly using a shared conceptual framework bringing together disciplinary-specific theories and concepts. There are numerous barriers that can obstruct effective communication between different cultures, communities, religions and geographies. This book shows that through bringing together different disciplines, researchers not only can surpass these barriers but can effectively produce new venues of thought that can positively affect the development and evolution of research and education. The book discusses new and emerging applications of knowledge produced by transdisciplinary efforts and covers the interplay of many disciplines, including agriculture, economics, mathematics, engineering, industry, information technology, marketing, nanoscience, neuroscience, space exploration, human-animal relationships, among others. Consequently, it also covers the relationship between art and science, as one of the most remarkable transdisciplinary approaches that paves the way for new methods in engineering, design, architecture and many other fields.
Common Pediatric Diseases: Current Challenges provides an update on different diseases and problems that affect child and adolescent health. The book starts with a quick introduction to challenges in the field of pediatrics and child health. This is followed by chapters on the outcomes of sexting, the integrated care of children with neurodevelopmental disorders, the influence of non-genetic transgenerational inheritance on children and adolescents' development and the approach to pediatric genetic epilepsy. Additional topics covered in the book include the medical and social outcomes of cardiac diseases along with a review on specific aspects of fetal and neonatal medicine (meconium-stained newborns, transient tachypnea of newborns and fetal tumors). The book also features a chapter on Autism Spectrum Disorder during infancy and its early symptoms. The concluding chapter covers medical futility controversies and end-of-life care.
The ¿Integrated Science of Global Epidemics¿ is the new proposed volume of Integrated Science Book series, aiming to publish the results of the most updated ideas and reviews on Global Epidemics. The whole world is suffering from complex problems, border less problems and global solution should be developed. The Integrated Science of Global Epidemics aims to highlight the combination of different disciplines, including formal sciences, physical-chemical sciences and engineering, biological sciences, medical sciences, and social sciences, to deal with complex problems such as global epidemics. This contributed volume could be used as guidelines for the entire scientific community and policy makers to successfully face these global threats.Chapter 27 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Tuberculosis have been documented since antiquity and the search of the microbes that cause this disease started more than three hundred years ago. Nevertheless, tuberculosis remains an important global health issue, with millions of people affected per year in addition to millions that remain undiagnosed and untreated. Patients with tuberculosis face the full range of recurrence, reinfection, and resistance due to diagnostic, prophylactic, and therapeutic procedures that are not as effective as they should be. In addition, variability in susceptibility to tuberculosis pose a complex problem with numerous interrelated variables. This volume is devoted to the understanding of Tuberculosis focusing on its heterogeneity, its transmission, manifestations, related conditions, diagnosis, treatments, drug resistance and prevention.
This book intends to investigate the broad spectrum of genetic changes in immunological processes involved in cutaneous diseases. One of the main goals of immunogenetic studies is finding susceptibility genes for complex diseases. This can provide an insight into the pathogenesis of the condition in a way that is not easily achievable through other kinds of studies. Thus they are a rational initial step for generating hypotheses about disease pathogenesis. This may especially benefit dermatology, a field notorious for having too many diseases with unknown etiologies.Immunogenetic investigations have made targeted treatment strategies possible for diseases such as psoriasis and pemphigus. Even though these strategies have revolutionized the management of chronic dermatological conditions such as psoriasis, still there are a lot of unanswered questions. For instance, psoriasis patients respond very differently to each of the commercially available biological agents. This diversity could be partially explained by the differences in the sets of genes responsible for disease induction in each individual. Thus whole genome sequencing strategies, if feasible at individual levels, might help in tailoring these targeted treatments based on specific genetic backgrounds.Our intention in preparing this book was to explore the broad spectrum of the genetic aspects of immunological processes involved in cutaneous diseases. We have tried to cover most areas of dermatology where enough studies were available to gather a chapter. Still, there is a substantial lack of knowledge on the immunogenetics of many dermatological conditions. We hope that this book would encourage the investigators to fill these gaps of knowledge.
The "e;THINKING: Bioengineering of Science and Art"e; is to discuss about philosophical aspects of thinking at the context of Science and Art. External representations provide evidence that the fundamental process of thinking exists in both animal subjects and humans. However, the diversity and complexity of thinking in humans is astonishing because humans have been permitted to integrate scientific accounts into their accounts and create excellent illustrations for the effects of this integration. The book necessarily begins with the origins of human thinking and human thinking into self and others, body, and life. Multiple factors tend to modify the pattern of thinking. They all will come into play by this book that brings thinking into different disciplines: humanities, natural sciences, social sciences, formal sciences, and applied sciences. The thinking demands full processing of information, and therefore, the book considers the economy of thinking as well. The book thoroughly intends to explore thinking beyond the boundaries. Specifically, several chapters are devoted to discipline this exploration either by artistic thinking alone or by art and mathematics-aided engineering of complexities. In this manner, the book models variations on thinking at the individual and systems levels and accumulates a list of solutions, each good for specific scenarios and maximal outcomes.
The contributed volume "e;Multidisciplinarity and Interdisciplinarity in Health"e; is a health-centered volume of the Integrated Science Book series. Lack of confidence, lack of expertise, complexities of healthcare, the confusing nature of healthcare environments, and lack of organization and standardization can become obstacles to successful communication. This volume establishes how extensive is the interface between formal sciences and medical sciences on health-related issues. The book provides an overview of the value of the integration of formal, biological, and medical sciences and related products, i.e., health informatics and biomedical engineering, to frame a holistic approach to health systems, healthcare, medical practice, drug discovery, and medical device design. The book also focuses on innovative solutions to the most critical issues of different health crisis, including obesity, infectious outbreaks, and cancer that can be found by using an integrative approach. It also contains the fascinating crossroads between medical sciences, physics, and mind that is discussed from multiple perspectives on cognition, neuroscience, and psychiatry. These multidisciplinary considerations will expand the concepts of creativity, leadership, aesthetics, empathy and mental health.
Translational Autoimmunity: Advances in Autoimmune Rheumatic Diseases, Volume Six addresses autoimmune diseases classified under the category of rheumatic diseases. Rheumatic diseases are heterogeneous groups of disorders in which inflammation affects not only joints, but also tendons, ligaments and bones. This updated release focuses on immunopathogenesis and clinical and laboratory details of rheumatic diseases, including rheumatoid arthritis, systemic lupus erythematosus, psoriatic arthritis, osteoarthritis and Sjogren's syndrome, and will be of interest to researchers, students and clinicians interested in autoimmune diseases, especially rheumatic diseases. From an introduction to rheumatic diseases to diagnostic laboratory tests, and from the microbiota-immunity to cell-based therapies, the bench to bedside approach to rheumatic diseases is the main subject of discussion in this comprehensive resource.
Common Pediatric Diseases: An Updated Review informs the reader about common diseases in children that are encountered by pediatricians and family physicians. Each of the 14 chapters in the volume presents updated information for readers with the aim to give them a current perspective on the topic. This book is a handy and practical compendium for medical students and healthcare professionals involved in general practice and pediatric clinics.The text starts with a quick introduction to pediatric diseases, before progressing towards specific diseases in children. The list of topics in this book includes pediatric rheumatological diseases, common oral diseases, pediatric metabolic syndromes, pediatric epilepsy syndromes, pediatric demyelinating disorder, genetic epileptic encephalopathies (with an algorithmic diagnostic approach), Henoch-Schonlein purpura, atopic dermatitis, childhood-onset systemic lupus erythematosus, Severe Combined Immunodeficiency, PFAPA, aphthous stomatitis, pharyngitis, cervical adenitis syndrome and pediatric hepatoblastoma.
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