Bøker av Nitish Kumar

This book discusses the importance of plants in terms of their natural bioactive products and medicinal, nutraceutical and health benefits. Plants are natural sources of many pharmaceutical compounds used in traditional and modern medicine, and their mass production and efficient use is imperative in view of the new emerging diseases. This book covers breakthroughs in the research of plant natural products by focusing on how different state-of-the-art biotechnologies facilitate their discovery, the molecular basis of their biosynthesis, as well as synthetic biology. Research on plant's natural products in the pre-genomic era was focused on discovering bioactive molecules with pharmaceutical activities, and identifying individual genes responsible for biosynthesis. In the post-genomics era, however, integration of inter-disciplinary approaches and detailed analysis of all accessible data from multi-informatics is necessary. This would accelerate the full characterization of biosynthetic and regulatory circuit for producing plant natural products.This book is an important reference book for the researchers working in the field of plant natural products and pharmaceutical industries at global level.

This edited book brings together a diverse group of environmental science, sustainability, and health researchers to address the challenges posed by global mass poisoning caused by heavy metals contamination of soil and plants. In recent years, contamination of the environment by heavy metals has become a major concern. Their multiple industrial, domestic, agricultural, medical, and technological applications have led to their wide distribution in the environment, raising concerns over their potential effects on human health and the environment. Owing to their toxic, non-degradable, and bio-accumulative nature, the health burden on the population has increased significantly. Heavy metals such as arsenic, lead, mercury, cadmium, and uranium do not play a significant role in metabolism in the human body and are thus toxic. Their exposure in high concentration can cause acute toxicity resulting in acute health conditions, which is easy to observe and regulate, while similar is not visible for immediate action when their exposure is in trace amounts over the years. Heavy metals enter in the food chain through consumption of plant material. A high concentration of heavy metals has been found to be harmful to vegetation. As the heavy metals concentration in plants increases, it adversely affects several biological parameters and eventually renders the soil barren.The book sheds light on this global environmental issue and proposes solutions to contamination through multi-disciplinary approaches and case studies from different parts of the world. This book is a valuable resource to students, academicians, researchers, and environmental professionals who are doing field work on heavy metals contamination throughout the world.

Arsenic contamination in drinking water and crops is a major health issue in many countries worldwide, threatening the health of millions of people due to arsenic¿s toxicity and carcinogenicity. This edited volume brings together a diverse group of environmental science, sustainability and health researchers to address the challenges posed by arsenic contamination. The book sheds light on this global environmental issue and proposes solutions to aquatic contamination through multi-disciplinary sustainable approaches and case studies from different parts of the world. The chapters contained here present the status quo in different parts of the world and provide essential information on arsenic exposure risks for humans as well as possible measures for tackling arsenic poisoning. The mechanisms of arsenic uptake, translocation and distribution in plants and grains are also explained. In closing, the book reviews a variety of prospective sustainable solutions to the problem of arsenic accumulation in soil and water. The book is comprised of three sections. The first section describes the routes of exposure to environmental arsenic and its transport in soil and aquatic ecosystems. The second section explains the health risks linked to arsenic exposure in food and the environment. The third section addresses sustainable arsenic contamination mitigation strategies using the potential applications of recent biological technology such as biotechnology, bioremediation, phytoremediation, biochar, absorbent, genetic engineering, and nanotechnology approaches. The book is intended for a broad audience including researchers, scientists, and readers with diverse backgrounds.

This book emphasizes recent developments in the use of mutation technologies for crop plant improvement and, ultimately, sustainable development. Plant breeders use genetic variation, which is created by plant-induced mutation, to create new and improved cultivars. The development of improved cultivars is a productive and optimistic agricultural strategy for economic and environmental sustainability since it ensures high yield stability, enhances soil health, and poses no environmental risks. Understanding mutation induction and exploring its uses have paved the road for improving genetic diversity for different plants and agronomic features and advanced gene discovery for diverse qualities that aid in sustainable development. Plant mutation breeding imitates spontaneous mutation, the primary force driving evolution, by using a plant's own genetic resources instead of genetic transformation. In order to develop beneficial agricultural features, this strategy focuses on the application of various chemical and physical mutagens in conjunction with biotechnologies. In order to survive in challenging environments, increase nutritional value, fight diseases and pests, grow in salty soils, and utilize water and nutrients more effectively, new varieties of plants are developed.This approach has significantly boosted the economies of nations like China, India, Japan, Pakistan, and the USA. As of right now, the strategy has produced and disseminated more than 3600 mutant types in the majority of crop plants, having a significant economic impact. This book discusses several mutation induction techniques, mutant screening, genome editing, the haploid breeding system for mutations, as well as genomic developments, and mutant gene identification. Plant breeders, researchers, and students in the fields of plant sciences, agriculture, and food science will find this instructive book to be of great help.

Mercury is a naturally occurring element that is toxic in nature. According to the US Environmental Protection Agency, the safe limit of mercury ion in drinking water is 10 nM to avoid the serious health problems to humans. Mercury is a pollutant of global concern. Both anthropogenic activities and natural processes cause its release into different spheres of the environment resulting in severe adverse impacts. Increased anthropogenic discharge of mercury leads to disturbance in its natural biogeochemical cycle which results in to unenviable diseases and hazardous health effects.This book will provide state-of-the-art information to the graduate students training in toxicology, risk assessors, researchers and medical providers at large. Many monographs, book chapters, contemporary reviews, and peer reviewed articles about mercury health impact are also available worldwide. However, there is no complete understanding available on toxicological studies of mercury, which coversthe broader spectrum of findings that range from sources of exposure to mercury toxicity as well as its remediation strategies. It is aimed to bring the readers updated information about the sources of mercury contamination, and its impact on human health and on prospective mitigation strategies through multi-disciplinary approaches. The book contains three sections. First section describes the different sources and distribution of mercury in the environment. Second section explains the health risks linked to mercury poisoning. Third section addresses sustainable mercury toxicity mitigation strategies through multi-disciplinary approaches. The key topic of this book will cover following: -Source and distribution of mercury in the environment-Effects and responses of mercury toxicity in plants- Health risk linked to mercury poisoning- Sustainable mercury toxicity mitigation strategiesThis book is a valuable resource to students, academics, researchers, and environmental professionals doing field work on mercury contamination throughout the world.

Industrial crops offer farmers new market opportunities to increase their revenue by producing high-value products, focusing on fiber, forest, and energy crops, industrial oilseeds, rubber and resins, pharmaceuticals, and more. Technological innovations in agriculture have facilitated higher yields, but conserving crop genetic resources and diversity remains crucial for sustainable agricultural production. This poses a challenge that can be addressed through modern tools of biotechnology and genomics, utilizing the wealth of sequenced plant genomes. This book addresses the need for knowledge in managing the risks and conservation of genetic diversity associated with advanced technology. It provides comprehensive coverage of plant genomics and biotechnology, catering to post-graduate students, researchers, employees of seed and biotechnology companies, as well as instructors in plant genetics, breeding, and biotechnology fields.

This book covers cadmium contamination of soil and plants, its sources, acute and long-term impacts on the environment and human health, and overall challenges posed by the global poisoning issue. Cadmium is among the elements that have been most broadly used by man over time, which has led to extensive pollution of surface soils, mainly associated with the mining and smelting of the metal and the addition of organic cadmium compounds to petrol. The release of cadmium into the atmosphere from various high-temperature processes has also led to surface contamination on a regional and even global scale. Cadmium is particularly firmly bound to humic matter in organic-rich soil and to iron oxides in mineral soil and is rather immobile in the soil unless present at very high concentrations. Plants grown on cadmium-rich soils incorporate cadmium, thus increasing the concentration of cadmium in crop plants. Cadmium thus enters the food chain through the consumption of plant material, whichposes important health risks to humans and animals. In this book, readers will find out about the latest mitigation strategies, including a multi-disciplinary approach to address cadmium contamination. Recent methods in cadmium detoxification, speciation, and molecular mechanisms are included, and the book offers the knowledge required for efficient risk assessment, prevention, and countermeasure. Divided into 3 parts, this book brings together expert contributions on cadmium toxicity. In the first part, readers will find out about the different sources and distribution of cadmium in soil and plant ecosystems. The second part of the book outlines the health risks linked to cadmium toxicity, and in the final part, readers will discover sustainable cadmium toxicity mitigation strategies and potential applications of recent biological technology in providing solutions. This book is a valuable resource for students, academics, researchers, and environmental professionalsdoing fieldwork on cadmium contamination throughout the world.

This edited book brings together a diverse group of environmental science, sustainability, and health researchers to address the challenges posed by global mass poisoning caused by chromium contamination of soil and plants. In recent years, contamination of the environment by chromium has become a major concern. Chromium is a non-degradable, harmful, and toxic pollutant which negatively affects the environment. It is unique among the heavy metals found in industrial wastewater and sewage and sludge, as it may exist as a trivalent cation and as anion in the hexavalent state in the pH range of agricultural soils. It is used on a large scale in many different industries, including metallurgy, electroplating, production of paints and pigments, tanning, wood preservation, chemical production, and pulp and paper production. These industries are contributing larger amount of chromium, which can ultimately have significant adverse effects on biological and ecological activities of ecosystem. Chromium enters the food chain through consumption of plant material. A high concentration of chromium has been found to be harmful to vegetation. As the chromium concentration in plants increases, it adversely affects several biological parameters and eventually renders the soil barren.The book sheds light on this global environmental issue and proposes solutions to contamination through multi-disciplinary approaches and case studies from different parts of the world.This book is a valuable resource to students, academicians, researchers, and environmental professionals who are doing field work on chromium contamination throughout the world.

This book presents mercury toxicity with respect to remediation and health issues. It covers sources of mercury contamination, its impact on human health, and prospective remediation by both bioremediation and phytoremediation with the application of recent advanced techniques such as genetic engineering and nanotechnology.Both anthropogenic activities and natural processes cause the release of mercury into different spheres of the environment resulting in severe adverse impacts. Increased anthropogenic discharge of mercury leads to disturbance in its natural biogeochemical cycle, which results in unenviable diseases and hazardous health effects. Mercury pollution is responsible for causing neurobehavioral, kidney, heart, gastrointestinal, liver, and other diseases. Many published works about the impact of mercury on health are also available worldwide; however, there is no complete understanding available on toxicological studies of mercury that covers the broader spectrum of findings ranging from sources of exposure to mercury toxicity to its remediation strategies.This book brings together a diverse group of environmental science, sustainability, and health researchers to address the challenges posed by global mass poisoning caused by mercury contamination. The book also proposes solutions to contamination through multi-disciplinary approaches.The book contains three sections. The first part describes the different sources and distribution of mercury in soil and plant ecosystems. The second part explains the health risks linked to mercury toxicity. The third part addresses sustainable mercury toxicity mitigation strategies and the potential applications of recent technology in providing solutions. This book is a valuable resource to students, academics, researchers, and environmental professionals working in the field of mercury contamination.

This book provides a comprehensive introduction and review of state-of-the-art biotechnological tools in enhancement of bioactive compounds in medicinal and aromatic plants. Plant bioactive compounds are plant-based natural products that display a variety of pharmacological applications. These bioactive compounds are important as medicines, pigments, flavorings and drugs because most of the pharmaceutical industries are highly dependent on medicinal plants and their extraction. The book introduces a systematic overview of state-of-the-art biotechnological techniques such as Omics, Crisper /Cas9 and RNAi to enhance the plant bioactive contents as well as enlists various in vitro techniques, hairy root culture and transgenic technology to enhance plant bioactive contents using plant tissue culture approaches. The book also provides an overview of the role of induced mutation, biotic and abiotic stress to increase the bioactive contents in plants and discusses the significant role of endophytes to enhance the contents of plant bioactive compound. The book also opens discussions related to standard operating procedures using hydroponics system of cultivation for significant enhancement of bioactive compound(s) and much more. This book serves as an excellent reference book for the researchers working in the field of plant secondary metabolites and pharmaceutical industries at global level.

This edited book covers the applications of molecular markers in the genetic improvement of crop plants. Recent advances in molecular marker techniques such as the development of high-throughput genotyping platforms, marker-assisted selection, and non-coding RNA-based markers have been discussed. Essential information is provided on functional markers, genotype-by-sequencing, and association mapping methodologies that can facilitate accelerated crop breeding programs for increased yield, high nutritional quality, and tolerance to a variety of abiotic and biotic stresses. This volume presents basic information on molecular marker techniques from marker location up to gene cloning. The book includes a description of technical approaches in genome analysis such as comparison of marker systems, positional cloning, and array techniques. This book is of interest to teachers, researchers, and plant breeders. The book also serves as additional reading material for undergraduate and graduate students of agriculture, horticulture, and forestry.

Arsenic (As) is a widely distributed element in the environment having no known useful physiological function in plants or animals. Historically, this metalloid has been known to be used widely as a poison. Effects of arsenic have come to light in the past few decades due to its increasing contamination in several parts of world, with the worst situation being in Bangladesh and West Bengal in India. This edited volume brings together diverse group of environmental science, sustainability and health researchers to address the challenges posed by global mass poisoning caused by arsenic water contamination. The book covers sources of arsenic contamination, and its impact on human health and on prospective remediation both by bioremediation and phytoremediation. Applications of advance techniques such as genetic engineering and nanotechnology are also discussed to resolve the issue of arsenic contamination in ground water and river basins.  The book sheds light on this global environmental issue, and proposes solutions to remove contamination through a multi-disciplinary lens and case studies from Bangladesh and India. The book may serve as a reference to environment and sustainability researchers, students and policy makers. It delivers an outline to graduate, undergraduate students and researchers, as well as academicians who are working on arsenic toxicity with respect to remediation and health issues.