Bøker av Rajesh Kumar Singh

This book provides an update on heterocyclic compounds that serve as key components of anti-cancer agents administered in pre-clinical settings. Many of the compounds highlighted in the book are being actively investigated for the bioactive properties against a range of cancer cell lines. There is potential for heterocyclic compounds to design agents that can target specific molecules to treat different types of cancers. Chapters are contributed by experts in pharmaceutical chemistry and are written to give a general overview of the topic to readers involved in all levels of research and decision-making in pharmaceutical chemistry and anti-cancer drug design. Part 2 of the book set covers these topics: - Anticancer targets for heterocyclic lead compounds - Coumarin hybrids for cancer treatments - Progress in nitrogen and sulphur-based heterocyclic compounds for their anticancer activity - Imidazole as an anticancer heterocyclic ring - Morpholine for profiling anticancer lead compounds - Natural products as anticancer agents

This book provides an update on heterocyclic compounds that serve as key components of anti-cancer agents administered in pre-clinical settings. Many of the compounds highlighted in the book are being actively investigated for the bioactive properties against a range of cancer cell lines. There is potential for heterocyclic compounds to design agents that can target specific molecules to treat different types of cancers. Chapters are contributed by experts in pharmaceutical chemistry and are written to give a general overview of the topic to readers involved in all levels of research and decision-making in pharmaceutical chemistry and anti-cancer drug design.>Part 1 of the book set covers these topics: >- The role of terpenoids as anticancer compounds: an insight into prevention and treatment - Recent advances in synthesis and anticancer activity of benzothiazole hybrids as anticancer agents - Structure-activity relationship (sar) studies of novel hybrid quinoline and quinolone derivatives as anticancer agents - Tetrazoles: structure and activity relationship as anticancer agents - Progress in nitrogen and oxygen-based heterocyclic compounds for their anticancer activity: an updates (2017-2020)

This monograph is meant for advanced researchers of South Asian architecture of the ancient times. Here you will find a novel periodisation system to better understand how the rock-cut architecture developed across time.Many unknown and lesser known facts will be found here suggesting that the rock-cut monuments of India developed through eight periods and five intervals. Data and interpretations will be found that indicate that on several junctures the Deccani rock-cut art and architecture were inspired by some compelling Gandh¿ran ideas.There were also some junctures when Deccani ideas inspired the developments in other lands, such as Kucha in Central Asia. It is also revealed how the early Kuchean 'central pillar caves' inspired the later developments in the Buddhist caves of Aurangabad and the ¿aivite cave temples of Konkan and the Deccan.The periodisation system may be useful when no other reliable data such as inscriptions are available.

This monograph is meant for the researchers of South Asian studies with a focussed interest on the history and art of the late fifth century CE.The new study proposes a reconstructive chronology of the times. It clarifies that the fifth-century rock-cut monuments of India were all Buddhist with only a few exceptions. The excavations had begun in the peaceful times of circa 461/462 CE. However, by circa 480 CE all the cave temples were abandoned even before completion. The study re-examines the cause of the abandonment and presents some new revelations.It was ca. 465 CE when the Hephthalite H¿¿s attacked the Early Alchon H¿¿s in the Greater Gandh¿ra region forcing the Buddhist monks to disperse inter alia towards the Deccan, which was then peaceful. ManyBuddhist rock-cut sites were flourishing there under the Gupta-V¿k¿¿aka-Traik¿¿akas: Bagh, Ajanta, Ellora, Mah¿¿, Dh¿r¿¿iva (Jain), Banö¿, Ghäotkaca, Nasik, Lö¿¿, Kondavite, and Kanheri.The ousted Alchons led by Mah¿¿¿hi Kh¿¿g¿la (r. ca. 440 to 492-496 CE) advanced into India and came up to the Narmada-Tapti valleys. The new intrusions witnessed many battles, particularly those of ca. 469, 472, and 477 CE wherein many great Indian emperors and kings were perished: Kum¿ragupta I, N¿gabhäa, Ghä¿tkacagupta, Skandagupta, Narasimhagupta, Narendra Sena, Ravis¿mba, Kum¿ragupta II, Hari ¿e¿a, and Dahrasena.These disturbances in India now forced the migrant Gandh¿ran and the resident Deccani monks to escape to distant lands including Kucha in Central Asia. Consequently, there was catalysed the Kuchean Period III, which witnessed the introduction of many Gandh¿ran and Deccani ideas.Finally Buddhagupta ousted the Alchons in ca. 478 CE. The persistent defeat had taught the Alchons a lesson. They now imbibed the Indian values of liberalism as statecraft, which allowed them unobstructed rule for the next one century and two decades (ca. 479-ca. 600 CE) when they ruled from Greater Gandh¿ra to the Narmada valley.The new picture comes out when we attempt to synchronise and iron out the anachronisms from the known chronologies of the Early Alchons, Early Guptas, V¿k¿¿akas, Traik¿¿akas, Gandh¿ra, and the rock-cut monuments of India and Kucha in the late 5th century CE. It is revealed that the monasteries were abandoned due to the attacks by the Early Alchon H¿¿s.

This book contains: Colour photographs of 70 Ajanta narrative paintings. 84 abridged Buddhist legends. Elementary introduction to the Ajanta paintings. Information based on the current research. A window to deeper studies. References to the scholarly works that first identified the nearest textual sources of the painted legends.

The monograph contains 15 Buddhist legends painted on the walls of Ajanta Cave No. 1 in the latefifth centry CE. All episodes of the stories are arranged in the same way as the painters painted them.It is a compendium of the ancient paintings systematically documented for the first time with colourphotographs.The monograph covers 14 of the total 15 narrative paintings of Cave 1. It has at least one photo ofevery episode of the narratives. It has systematically arranged material in accordance with the Ajantacorpus of Dieter Schlingloff.There is summary of all the 15 legends. The picture descriptions are based on up-to-date research oneach painted episode. There is a concise bibliography of the nearest textual concordance of thenarratives in the Buddhist scriptures.Dr. Rajesh Kumar Singh has spent nearly fifteen years to study the Ajanta caves in detail. Prior to this,he has published, produced, or edited 2 monographs, 11 research papers, a CD-Rom, and 5 videos onAjanta. The contents of this monograph is meant for academic libraries, educators, students, andgeneral readers.