Bøker av Rajesh Pandey

Genomic Surveillance and Pandemic Preparedness offers practical, in-depth instruction in where, how, and why genomic surveillance may be applied. Drawing heavily from the learnings during the COVID-19 pandemic, this book covers different aspects of microbes with a focus on viral genome sequencing and analysis, implementation and inference of genomic surveillance, and global data sharing best practices for future pandemic preparedness. Here, more than a dozen international authors consider host and pathogen genome interaction, population-level prevalence, individual disease susceptibility and gene protection, pathogen mutation evolutionary dynamics, RNA modulation of infection, pathogen diversity, and the role of coinfections and comorbidities in disease severity. A wide range of examples, from bacterial pathogens to fungal and viral infections, with an emphasis on recent COVID-19 analysis, are discussed. Finally, the authors provide step-by-step instruction in experimental and computational approaches for genomic surveillance, including nucleic acid isolation, sequencing library preparation, functional sequencing analysis, and bioinformatics pipelines. Throughout this book, importance is placed on inference-moving from genomic sequencing to meaningful genomic surveillance that bolsters pandemic preparedness.

In an uncertain future, a leader would rise to power in America. General George Rath is supremely charismatic, extraordinarily bold, and eerily intelligent. Rath's powerful aura would change the political and social structure of America forever. His meteoric rise to power would sweep the country up in a maelstrom of hysteria. But Colonel James Bradford had looked into Rath's eyes and had seen a frightening power that lurked inside. As he desperately attempts to uncover the mystery behind Rath's extraordinary power, he becomes entrapped in a horrifying web of betrayal and corruption. And although Bradford's daughter Alexandria is born at a terrible cost, she carries unimaginable powers of her own. She becomes engaged in a struggle to survive against terrifying enemies, as Rath's menacing shadow shrouds her future. With her own demons screaming inside of her, testing her will and the limits of her powers, Alexandria could be the only hope for a world that is spiraling toward unthinkable devastation. The three individuals must journey through searing landscapes of fear, chaos, and conflict, across the very boundaries of human existence on a collision course with the fate of the world...