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Applications of nanoparticles to the human life and tools in diagnosis and therapy in field of clinical medicine holds importance and has been an prime focus of biomedical and clinical research for quite sometime, though their application in veterinary medicine is a relatively new focus area of research. Prior to human applications, studies are initially conducted on animals models. Thus toxicity based studies and study of impact of nanoparticles on animal immune system finds importance. In the second volume of the book we discuss the immune system in animals across invertebrates and vertebrate phylas and discuss the impact of nanoparticles in animals life, health, survival and immune system. The book highlights the toxic effects of nanoparticles as environmental pollutants and their adverse impact on animal life forms. Both volumes are also included in a set ISBN 978-3-11-065666-4.
This book explores the latest developments in the field the acute phase protein (APP), C-reactive protein or CRP in different diseases, highlighting the structural and functional aspects of CRP in disease biology.Divided into 5 sections, the book examines important topics such as the role of CRP in neurodegenerative, cardiac and parasitic diseases, as well as in cancer and inflammatory bowel disease, and the expression of CRP in pediatric respiratory diseases. In addition it discusses the clinical role of CRP in diagnostics and therapeutics, sepsis, ICU and ITU patients, and also as a primary marker for inflammation. Given its scope, this book will appeal to scholars in various fields of medicine and biology.
This monograph summarizes the current knowledge on potential health hazards induced by nanomaterials from different sources and sort such as food, drugs and silver nanoparticles. Methods to assess toxicity as well as known effects on the genome, neuronal and respiratory system are discussed. Besides the impact on human and animal life the books also addresses aquatic toxicity.
Stem cells hold great promise for cell therapy, tissue engineering, regenerative medicine and pharmaceutical and biotechnological applications. This book highlights the potency of stem cells, their property of self-renewal and their ability to differentiate into different cell lineages. It further describes the different markers to identify stem cells, sources, methods of isolation, culture including 2D, 3D and beyond and their cryopreservation. This is among the first books to discuss glycosylation and sialylation in stem cells. Chapters describe application of stem cells in regenerative medicine and therapy, and highlight their application in cancer therapy and spinal cord injury. The book talks about the important patents on stem cells. The book also highlights the plant stem cells, discussing their pluoripotent nature, role in organ regeneration after injury, specific stem cell niches, that signals to block differentiation studied in plants shoot, root, and vascular meristems, differentiation of plant stem cell, transcriptional regulation and epigenetic modification of plant stem cells. This book is exciting and cutting edge. It will be of great interest to doctors, students and researchers in the field of regenerative medicine, cancer , biotechnology and plant sciences.
The second volume focuses on the different applications of computational tools in immunology. The first component of the book explores data-driven algorithms, methods, data warehouses. The second component discusses computational approaches to understand the invertebrate immune system of model organism like Planaria, Hydra, Drosophila.
The first volume describes detailed complexity of the immune system in human and in invertebrates. It also gives an idea of different computational tools and techniques in understanding the complexity of immune systems.
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