Bøker av Upasana Sharma

This book is just not the book to read once and keep on a bookshelf. This book is a vision of the secrets we all hold within ourselves. The book comprises three stories, each holding its own secret vision and experiences. Each story has its own essence, its own beauty, which is just concealed by secrets and going to unfold by the vision which one holds through his power and experiences. We all have secret powers and visions that make us unique in a way that no one else can be. It's all about focusing on our inner capabilities and strength to know, and who knows what secret vision you hold!So, this book is all about the secrets that the eyes conceal. But still, it is as quiet as the falling petals. The flower petals fall so quietly that no one judges that they behold the sweetest fragrance within themselves.

The study is an attempt towards developing a formulation of an anti-estrogen drug, which belongs to non-steroidal aromatase inhibitor and which has in-vitro dissolution profile similar to that of reference product. Our target is to develop a dosage form similar to reference product for generic drug application to abbreviated new drug application (ANDA). Immediate drug delivery is required to alter the pharmacokinetics and pharmacodynamics of pharmacological active moieties by using physiological parameters inherent in the selected route of administration. It is also desirable to show rapid onset of action. In case of patient needing a quick action, conventional tablets are unable to release medicament rapidly. The drugs having long half-life and more bioavailability are beneficial for the formulation of immediate release dosage forms. Therefore, the present project involves the development of a formula for an orally administrable immediate release tablet of an anti-estrogen drug, letrozole which must be stable, bio-equivalent to reference listed drug product and has a reproducible and robust process of medication to prevent breast cancer relapse.