Bøker av Ying (University of Texas Yuan

This book shows how model-assisted designs can greatly improve the efficiency and simplify the conduct of early-phase dose finding and optimization trials. It should therefore be a very useful practical reference for biostatisticians, clinicians working in clinical trials, and drug regulatory professionals, as well as grad students.

This book is the first to focus on Bayesian phase I¿II clinical trials. It describes many problems with the conventional phase I¿phase II paradigm and covers a large number of modern Bayesian phase I¿II clinical trial designs.