Bøker av Zodwa Dlamini

This book explores the relationship between the gut microbiome and cancer, illuminating various facets from fundamental roles to personalized therapies. It provides a comprehensive overview of the impact of the gut microbiome on cancer development, offering potential for innovative diagnostic and treatment approaches. The book discusses the role of dysbiosis in cancer development, the influence of the microbiome on treatment responses, and strategies to modulate the microbiome for enhanced therapies. It also reviews the influence of the gut microbiome on immunotherapy resistance and chemoresistance in cancer patients. Additionally, the book presents gut microbiome biomarkers for cancer diagnosis and prognosis, the implication of the gut-brain axis on cancer development and progression, and the impact of diet and lifestyle on the microbiome. Towards the end, the book investigates the role of the gut microbiome in pediatric cancer and provides an outlook on the future challenges, technological advancements, and ethical considerations of gut microbiome research in the context of personalized cancer therapies. This book is intended for cancer researchers, medical oncologists, clinicians, pharmacologists, translational investigators, and medical students.

This book addresses the pressing problem of drug resistance in the treatment of breast cancer. It provides a comprehensive understanding of the complex mechanisms underlying drug resistance and presents the latest advances in therapeutic approaches to overcome this enormous challenge. The book begins with an introduction to the biology of breast cancer, treatment modalities and the mechanisms of drug resistance. This includes the principles of drug resistance in targeted, immune-, endocrine and chemotherapy. In the following sections, the authors present innovative strategies to overcome drug resistance and new research directions, among others the role of the microbiome in drug resistance, molecular profiling of patients for personalized medical care, and new drug delivery systems. Finally, the book concludes with a discussion of the differences in the prevalence and treatment success of breast cancer between high- and low-income countries. This book is an informative resource for students, researchers, and clinicians in the field of breast cancer research and oncology in general.

Strategies for Overcoming Chemotherapy Resistance in Cervical Cancer: From Molecular Insights to Precision Solutions, Volume 21 highlights different strategies to reverse chemotherapy resistance in cervical cancer. The book puts a strong focus on strategies to reverse chemotherapy resistance as well as strategies for early detection of the resistance, enhancing precision oncology in terms of patient care and maximizing patient management. The book also looks at virally induced resistance to chemotherapy and recommends combination therapies that can maximize the reversal of this resistance.In 10 chapters, the book not only gives an overview of cervical cancer and chemotherapy as treatment, but also investigates resistance to chemotherapy and treatment for resistance. It defines treatment mechanisms, options, and limitations to beat chemotherapy resistance and the reversal of the resistance mechanisms. It gives insights into future directions of cervical cancer treatment using epigenetic silencing, chemotherapy splicing, the involvement of MicroRNAs to chemotherapy resistance, and the application of Artificial Intelligence.