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Collectively, bioengineered tumors create an important resource for the in vitro study of tumor growth in 3D including tumor biomechanics and the effects of anti-cancer drugs on 3D tumor tissue.

This volume offers the most comprehensive coverage on fetal programming. Chapters are written by authors of international and national standing, leaders in the field and trendsetters. The clinical relevance of the current research is emphasized in each chapter, which also contains key points, key words, and concise summaries for ease of learning. Fetal programming affects conditions in the immediate postnatal period, as well as in later life and adulthood. These conditions include cardiovascular disease, frank hypertension, stroke, dyslipidemia, coagulopathy, increased insulin resistance-metabolic syndrome, type-2 diabetes, leukemia, testicular cancer, prostate cancer, breast cancer, polycystic ovary syndrome, precocious puberty, impaired immune function, renal disease, lung disease, and osteoporosis. Neuropathologies, behavioral and mental deficiencies, schizophrenia, and depression have also been reported in adults who were exposed to nutritional inadequacies in utero. Diet, Nutrition and Fetal Programming provides an overview on the effects of fetal programming on disease, and comprehensive looks at maternal nutrition factors and fetal programming effects on brain and behavior, and physiology and disease. It also provides an in depth look at specific nutrient restrictions and supplements on physiology and disease, the effects of maternal disease on fetal programming, mechanisms of programming, and a special section on the international aspects and policies on fetal programming.

Utilizing the most current evidence, this practical book is the first publication of its kind to focus exclusively on the clinical and laboratory evaluation and therapy of thyroid nodules, including advances in evaluation and controversies in management.

This volume will be the first to provide a comprehensive description of tumor dormancy. The volume will serve as a fundamental instrument for every researcher and clinician interested in the field of tumor dormancy as well as a means of disseminating stimulating concepts and prompting the development of innovative technological solutions.

This volume provides a comprehensive, state-of-the art review of the field of cell therapy.

The second edition of this text reviews the prevention, evaluation and management of complications arising from female pelvic surgery.

This book focuses on developments in complex dynamical systems and geometric function theory over the past decade, showing strong links with other areas of mathematics and the natural sciences.Traditional methods and approaches surface in physics and in the life and engineering sciences with increasing frequency - the Schramm-Loewner evolution, Laplacian growth, and quadratic differentials are just a few typical examples. This book provides a representative overview of these processes and collects open problems in the various areas, while at the same time showing where and how each particular topic evolves. This volume is dedicated to the memory of Alexander Vasiliev.

This highly readable book aims to ease the many challenges of starting undergraduate research. It accomplishes this by presenting a diverse series of self-contained, accessible articles which include specific open problems and prepare the reader to tackle them with ample background material and references. Each article also contains a carefully selected bibliography for further reading.The content spans the breadth of mathematics, including many topics that are not normally addressed by the undergraduate curriculum (such as matroid theory, mathematical biology, and operations research), yet have few enough prerequisites that the interested student can start exploring them under the guidance of a faculty member. Whether trying to start an undergraduate thesis, embarking on a summer REU, or preparing for graduate school, this book is appropriate for a variety of students and the faculty who guide them.

This book contains selected papers based on talks given at the "Representation Theory, Number Theory, and Invariant Theory" conference held at Yale University from June 1 to June 5, 2015.

This book investigates the convergence and summability of both one-dimensional and multi-dimensional Fourier transforms, as well as the theory of Hardy spaces.

This book discusses normal sex-related differences in lung structure and function and the role these differences play in lung disease.

This book discusses health disparities in respiratory medicine and suggests methods to reduce them. Similarly, differences in health and health outcomes exist between differing socioeconomic groups, with lower income groups generally having poorer health and higher rates of chronic illness.

The second edition of this book updates and expands upon a historically important collection of mathematical problems first published in the United States by Birkhäuser in 1981. These problems serve as a record of the informal discussions held by a group of mathematicians at the Scottish Café in Lwów, Poland, between the two world wars. Many of them were leaders in the development of such areas as functional and real analysis, group theory, measure and set theory, probability, and topology. Finding solutions to the problems they proposed has been ongoing since World War II, with prizes offered in many cases to those who are successful.In the 35 years since the first edition published, several more problems have been fully or partially solved, but even today many still remain unsolved and several prizes remain unclaimed. In view of this, the editor has gathered new and updated commentaries on the original 193 problems. Some problems are solved for the first time in this edition. Included again in full are transcripts of lectures given by Stanislaw Ulam, Mark Kac, Antoni Zygmund, Paul Erdös, and Andrzej Granas that provide amazing insights into the mathematical environment of Lwów before World War II and the development of The Scottish Book. Also new in this edition are a brief history of the University of Wroclaw's New Scottish Book, created to revive the tradition of the original, and some selected problems from it.The Scottish Book offers a unique opportunity to communicate with the people and ideas of a time and place that had an enormous influence on the development of mathematics and try their hand on the unsolved problems. Anyone in the general mathematical community with an interest in the history of modern mathematics will find this to be an insightful and fascinating read.

This new edition is devoted to a broad array of topics involving the circadian variation in cardiovascular diseases, with focuses on hypertension, stroke, and coronary disease. The volume covers clinical and device research related to home and ambulatory BP monitoring, as there have been significant advances in technology since the publication of the previous edition. In addition, there is an increased focus on the applicability of home and ambulatory BP monitoring in drug development in all therapeutic arenas. The text features contributions from chapter authors from around the world and who have great expertise in cardiovascular medicine, therapeutics, clinical trials, and evidence-based medicine.Blood Pressure Monitoring in Cardiovascular Medicine and Therapeutics, Third Edition is essential reading for a large audience, including those practicing cardiology and nephrology with a special focus in hypertension, geriatrics and internal medicine, clinical trialists, regulators in the US, Europe, and Japan, and physicians in training in cardiology, hypertension, pharmacology, nephrology and neurology.

Specific attention is devoted to the genetic manipulation of T cells through the introduction of re-directed T cell receptors, chimeric antibody receptors, and other genetic manipulation aimed at improving their effectiveness as anti-cancer agents.

This book features a series of lectures that explores three different fields in which functor homology (short for homological algebra in functor categories) has recently played a significant role.

This proceedings volume originates from a conference held in Herrnhut in June 2013. It provides unique insights into the power of abstract methods and techniques in dealing successfully with numerous applications stemming from classical analysis and mathematical physics. The book features diverse topics in the area of operator semigroups, including partial differential equations, martingale and Hilbert transforms, Banach and von Neumann algebras, Schrödinger operators, maximal regularity and Fourier multipliers, interpolation, operator-theoretical problems (concerning generation, perturbation and dilation, for example), and various qualitative and quantitative Tauberian theorems with a focus on transfinite induction and magics of Cantor.The last fifteen years have seen the dawn of a new era for semigroup theory with the emphasis on applications of abstract results, often unexpected and far removed from traditional ones. The aim of the conference was to bring together prominent experts in the field of modern semigroup theory, harmonic analysis, complex analysis and mathematical physics, and to present the lively interactions between all of those areas and beyond. In addition, the meeting honored the sixtieth anniversary of Prof C. J. K. Batty, whose scientific achievements are an impressive illustration of the conference goal. These proceedings present contributions by prominent scientists at this international conference, which became a landmark event.They will be a valuable and inspiring source of information for graduate students and established researchers.

This volume reflects "New Trends in Shape Optimization" and is based on a workshop of the same name organized at the Friedrich-Alexander University Erlangen-Nurnberg in September 2013. some focus on the topics discussed at the Workshop, while others involve arguments outside its scope but which are no less relevant for the field today.

This volume contains the contributions of participants of the conference "Optimal Control of Partial Differential Equations" which, under the chairmanship of the editors, took place at the Mathematisches Forschungsinstitut Oberwolfach from May 18 to May 24, 1986.

Those connected with drug research, be they in industry, in universities or in clinics, are aware of these problems, and, as a result of this awareness, are all the more in need of an aid which will assist them in ascertaining the current position and in fixing future goals.

While all articles deal with some of the topical aspects of drug research, the contribution by Al fred Burger on "Isosterism and bioisosterism in drug design" is of great value to those researchers who are engaged in drug design and wish to include isosteric considerations in establishing a work ing hypothesis.

During the period the sponges described herein were which were used only sporadically in the past and were collected (1963-7), the author was a Research Associate regarded as of marginal value until two decades ago, at the Department of Geology, University of Illinois, paleontology and embryology, are now receiving great participating in a research project on carbonate attention. They have already brought drastic revisions to sediments of the Bimini area, directed by Prof. William systematics, with regard to redefinition and classification W. Hay (Department of Geology, University of Illinois. of higher taxa. Other approaches have recently emerged utilizing biochemistry, histology, cytology, autecology, now at the Rosenstiel School of Marine and Atmospheric and zoogeography, and these promise significant ad­ Science, University of Miami) and supported by the National Science Foundation. The objective of this pro­ vance in the delimitation and classification oflower taxa. ject was a study of the relationship between the carbo­ The rapidly changing state of sponge taxonomy is reflect­ nate sediments of the Bimini area and the benthonic ed in the paucity of definitive (i. e. widely accepted) revisions of genera and families. The lack of stability and fauna and flora, especially with regard to skeletal ele­ ments contributed to the sediment.

This contributed volume contains articles written by the plenary and invited speakers from the second international MATHEON Workshop 2015 that focus on applications of compressed sensing.