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Synthesis of Epoxides explores different ways of making epoxides, both old and new, and delves into the growing field of heterocyclic chemistry. It's aimed at people who want a variety of methods and need help figuring out which one suits their specific needs. For students, having all the protocols for making epoxides in one place is handy because sometimes you just want to see all the options for creating a particular compound from a specific starting point. Diazo compounds are important synthetic intermediates in organic synthesis but, because of their unpredictable explosive nature and toxicity, their unique reactivity has not been fully exploited and their employment on large scale is avoided. The synthetic usefulness of diazo compounds cannot be overlooked despite their danger. Because of their ylide and 1,3-dipole nature, the diazo compounds have a unique reactivity. The diazo compounds can be utilized for various different conversions including S-ylide-assisted epoxidation, cyclopropanation, or aziridination reactions. This book describes the new and classic methods for the synthesis of epoxides and covers an important and rapidly growing branch of heterocyclic chemistry. Readers will learn about different methods and want information allowing them to evaluate which method is most suitable in particular cases. Students will be able to find the protocols for the synthesis of epoxides in one place within this book because sometimes we want to see all of the possibilities for synthesizing a particular compound from one particular substrate.

The first volume of the Hydrosystem Restoration Handbook offers a thorough introduction to Streamflow Recharge (SFR) and Lake Rehabilitation (LR). The book comprises global case studies that encompass the most up-to-date management approaches in streams. It provides comprehensive methods for sustainable water supply through debris removal, along with conservation practices, to assist researchers and graduate students specializing in this field.

In this issue of Medical Clinics of North America, guest editor Dr. Douglas Paauw brings his considerable expertise to the topic of Newer Outpatient Therapies and Treatments. Top experts provide insights into recent pharmacologic treatments, review new uses for old drugs, discuss new technologies used in the outpatient setting, and address complementary/alternative options with strong evidence..Contains 12 relevant, practice-oriented topics including therapy for hyperlipidemia; newer diabetes therapies and technologies; update on antiviral therapies; update in treatments for men's health; newer therapies for psychiatric disease; and more.Provides in-depth clinical reviews on newer outpatient therapies and treatments, offering actionable insights for clinical practice.Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Endocrinology and Metabolism Clinics of North America, guest editors Drs. Rachel Pessah-Pollack and Maria Papaleontiou bring their considerable expertise to the topic of Update on Endocrine Disorders During Pregnancy. In recent years, our understanding of endocrine disorders during pregnancy has greatly evolved and changed. In this issue, top experts provide updates on transgender reproductive health, PCOS management during pregnancy, hypertension, diabetes, congenital adrenal hyperplasia during pregnancy, and more.Contains 13 relevant, practice-oriented topics including hyperthyroidism during pregnancy; pregnancy-related bone loss; challenges of lipid management during pregnancy; Cushing's disease; and more.Provides in-depth clinical reviews on endocrine disorders during pregnancy, offering actionable insights for clinical practice.Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Primary Care: Clinics in Office Practice, guest editors Drs. Michael Malone and Vasudha Jain bring their considerable expertise to the topic of Endocrinology. Top experts provide practical approaches to the evaluation, diagnosis, management, and complications of common endocrinology disorders encountered in the primary care setting, including neuroendocrine tumors, endocrinology during pregnancy, endocrine emergencies, metabolic bone disease, thyroid disorders, and more.Contains 14 relevant, practice-oriented topics including female reproductive endocrine disorders; male reproductive endocrine disorders; pituitary disorders; obesity; sports endocrinology; and more.Provides in-depth clinical reviews on endocrinology, offering actionable insights for clinical practice.Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Sleep Medicine Clinics, guest editors Drs. Brendon Yee, Stephen McNamara, and Amanda Piper bring their considerable expertise to the topic of Multi-Perspective Management of Sleep Disorders. Top experts discuss the pathophysiology of chronic respiratory failure (hypercapnic); assessment (including diagnostic tests) of chronic hypercapnic respiratory failure; overlap syndrome; managing heart failure in patients with chronic respiratory failure; the impact of new drugs in improving and maintaining respiratory function; and much more.Contains 13 relevant, practice-oriented topics including interfaces for NIV; initiation of NIV; telemonitoring NIV; the role of high flow nasal therapy in chronic respiratory failure; airway clearance in NMD; NIV and quality of life; and more.Provides in-depth clinical reviews on multi-perspective management of sleep disorders, offering actionable insights for clinical practice.Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Infectious Disease Clinics of North America, guest editors Dr. Daniel A. Solomon and Paul E. Sax bring their considerable expertise to the topic of Advances in the Management of HIV. Top experts in the field review the state of the art in HIV treatment and prevention, discuss challenges and opportunities in reaching especially vulnerable populations, identify treatment challenges in an aging population, and look into the future of antiretroviral therapy, vaccine development, and training the next generation of the HIV workforce.Contains 14 relevant, practice-oriented topics including the pipeline of antiretroviral therapy; HIV pre-exposure prophylaxis; HIV vaccine: promise and challenges; progress in the search for an HIV cure; HIV in the South: an epidemic within an epidemic; and more.Provides in-depth clinical reviews on advances in the management of HIV, offering actionable insights for clinical practice.Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

System reliability has become the paramount attribute of any production unit. The process of maximizing system reliability while adhering to multiple constraints is referred to as reliability optimization. There are two primary approaches to enhancing a system's performance and reliability: developing a product with reduced failures (failure avoidance) or incorporating resilience to ensure the system continues functioning even in the event of a failure (fault tolerance). Recognizing the significance of system design in reliability optimization, 'Reliability Assessment and Optimization of Complex Systems' delves into a range of tools and techniques for designing optimized complex systems. Each chapter explores system modeling and the implementation of various metaheuristics for optimization purposes. This book provides readers in the domain of applied mathematics with a comprehensive understanding of system reliability analysis and improvement, thereby offering substantial value to their knowledge and expertise.

Green Machine Learning and Big Data for Smart Grids: Practices and Applications is a guidebook to the best practices and potential for green data analytics when generating innovative solutions to renewable energy integration in the power grid. This book begins with a solid foundation in the concept of "green" machine learning and the essential technologies for utilising data analytics in smart grids. A variety of scenarios are examined closely, demonstrating the opportunities for supporting renewable energy integration using machine learning, from forecasting and stability prediction to smart metering and disturbance tests. Uses for control of physical components including inverters and converters are examined, along with policy implications. Importantly, real-world case studies and chapter objectives are combined to signpost essential information, and to support understanding and implementation. Part of the cutting-edge series 'Advances in Intelligent Energy Systems', 'Green Machine Learning and Big Data for Smart Grids' provides researchers, students, and industry practitioners with an understanding of the complex interactions and opportunities between data science and sustainable energy systems.

In this issue of Anesthesiology Clinics, guest editors Drs. Neal H. Cohen and Gail van Norman bring their considerable expertise to the topic of Ethical Approaches to the Practice of Anesthesiology - Part 1: Overview of Ethics in Clinical Care: History and Evolution. In this first of a two-part series, top experts discuss topics such as the role of advance directives and living wills on anesthesia practice; preoperative care of the patient with DNR orders; end-of-life care: withdrawing/withholding support; brain death: medical, ethical, cultural, legal aspects; ethics consult in anesthesia practice; and more.Contains 14 relevant, practice-oriented topics including maternal-fetal conflicts in anesthesia practice; ethical care of pregnant patients for non-obstetrical surgery and during labor and delivery; caring for the patients whose personal/religious/cultural beliefs impact clinical management strategies; approaching the patient when a medical error occurs; and more.Provides in-depth clinical reviews on ethical approaches to the practice of anesthesiology, offering actionable insights for clinical practice.Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Obstetrics and Gynecology Clinics of North America, guest editors Drs. Amy VanBlaricom and Brigid McCue bring their considerable expertise to the topic of Obstetrics and Gynecologic Hospitalists and Laborists. Top experts provide clinical updates to help obstetrics and gynecology hospitalists stay current, including important topics such as restricted access to termination; medical innovations; crisis management; risk mitigation; and diversity, equity, and inclusion.Contains 14 relevant, practice-oriented topics including obstetric and gynecologic hospitalist fellowships; medical innovation for obstetrics and gynecologist hospitalists' practice and patient experience; the gynecologic hospitalist; can obstetrics/gynecology hospitalists reduce severe maternal morbidity; and more.Provides in-depth clinical reviews on obstetrics and gynecologic hospitalists and laborists, offering actionable insights for clinical practice.Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

When you become a ward or unit manager, or allied health professionals team leader, your responsibilities change and you need a very different set of skills compared to your previous roles. You are now required to manage a team of staff with a set budget and are responsible for maintaining an environment in which people can work together efficiently and effectively. This new fourth edition of the Survival Guide to Leadership and Management on the Ward welcomes Krishna Gohil to the author team and thereby extends its guidance on these crucial skills to both nurses and allied health professionals. This book will help you toIdentify your responsibilities and best approaches as a manager to provide patients with a high standard of care through your staffBecome an even better leader through highly practical examples, suggestions and tipsManage your staff, time and budgetCreate a positive work environmentFamiliarize yourself with the new NMC and HCPC standardsFocuses on both nursing and allied health professionals who are in the role of ward managers, unit managers or team leaders, or aspire to be soThis new fourth edition significantly builds on how to understand your role, work with different generations in the workplace and manage difficult situationsIncludes greater emphasis on self-care and self-compassion for leaders and managersCovers leading teams in the context of enduring financial and staffing constraints

Solar Energy Technologies in Cultural Heritage offers a complete overview of the solar renewable energy possibilities, developments, innovations, and challenges for cultural heritage applications, bridging the traditional boundary between research, professional practices, and policies, and between arts, architecture, engineering, and social science. Conservation of heritage buildings, particularly in urban settings, has evolved from purely physical preservation to making them functionally relevant for the modern day through redevelopment and repurposing. This opens the opportunity for the integration of active solar energy systems in buildings, towns, and landscapes. This book presents international contributions on the integration of solar renewable energies within cultural heritage, providing detailed coverage of the cultural, legislative, and social framework, design criteria and simulation tools, and innovative materials and technologies, and addressing key challenges. This is an essential resource for all those with an interest in solar energy technologies for built environment and particularly cultural heritage, including researchers, scientists, and graduate students, engineers, designers, developers, and policy makers.

Internet-of-Things' Cybersecurity in Critical Infrastructures: Case Studies in Energy Systems takes readers from the basic principles of cybersecurity in essential public infrastructure to the specific requirements of energy systems connected to the Internet-of-Things. This book provides a holistic approach to the challenges (legal, technological, and human) of AI and IOT integration for renewable, modern energy infrastructure. It outlines the fundamental challenges and technologies of cybersecurity for essential infrastructure and goes on to apply this specifically to energy grids and systems, in the light of the ML, AI, and IOT technologies required for renewable integration. Case studies are provided to ensure the reader is fully equipped to problem-solve and apply the knowledge in the development and planning of secure energy infrastructure. Packed with a wealth of practical experience and guidance, Internet-of-Things' Cybersecurity in Critical Infrastructures is a critical resource for energy system engineers looking for a primer on the cybersecurity needs of connected, renewable-integrated energy infrastructure.

Applications of Geospatial Technology and Modeling for River Basin Management covers the use of multi-temporal satellite data for accurate estimations of different watershed features. It includes methods and case studies of the use of geographic information systems (GIS) as a valuable tool for criteria-based spatial analysis to manage natural resources and accurately simulate natural phenomena such as the hydrologic response of a watershed to precipitation and susceptibility to water erosion. The book also provides direction on many types of modelling and mapping techniques in geospatial environments based on river basin management challenges. Applications of Geospatial Technology and Modeling for River Basin Management is a useful guide for academics, researchers, and practitioners involved in the use of geospatial technologies for river basin management, as well as those interested in environmental management and Earth surface geomorphology.

Machine Learning for Powder-based Metal Additive Manufacturing outlines machine learning (ML) methods for additive manufacturing (AM) of metals that will improve product quality, optimize manufacturing processes, and reduce costs. The book combines ML and AM methods to develop intelligent models that train AM techniques in pre-processing, process optimization, and post-processing for optimized microstructure, tensile and fatigue properties, and biocompatibility for various applications. The book covers ML for design in AM, ML for materials development and intelligent monitoring in metal AM, both geometrical deviation and physics informed machine learning modeling, as well as data-driven cost estimation by ML. Optimization for slicing and orientation, ML to create models of materials for AM processes, ML prediction for better mechanical and microstructure prediction, and feature extraction by sensing data are all covered, and each chapter includes a case study.

Corrosion Engineering: Principles and Solved Problems, Second Edition gives a comprehensive overview and introduction to the field through an extensive theoretical description of the principles of corrosion theory, passivity and corrosion prevention strategies and design of corrosion protection systems. The second edition has been thoroughly updated with new knowledge and includes solved corrosion case studies, corrosion analysis and solved corrosion problems to help the reader to understand the corrosion fundamental principles from thermodynamics and electrochemical kinetics, the mechanism that triggers the corrosion processes at the metal interface and how to control or inhibit the corrosion rates. A key goal of the updated book is to help the next generation of engineers and scientists: (i) understand the theory of hydrogen embrittlement and stress corrosion cracking as well as hydrogen damage prevention strategies, (ii) design models for developing hydrogen damage-resistant alloys, and (iii) prevent damage of different industrial components due to the presence and localization of hydrogen in metals. To accomplish these objectives, the book offers case studies of hydrogen permeation, hydrogen embrittlement, mechanical properties of alloys, and hydrogen damage control. The book covers the multidisciplinary nature of corrosion engineering through topics from electrochemistry, thermodynamics, mechanical, bioengineering, and civil engineering as well as materials science. It will appeal to students and instructors studying or teaching upper undergraduate/graduate level courses as well as researchers, and engineers in industry across these areas.

Advanced Oxidation Process-based Integrated and Hybrid Technologies for Degradation of Pharmaceuticals and Personal Care Products addresses the PPCPs removal from wastewater by the recent application of AOP-based hybrid techniques. Technological advancement of AOPs and AOP-based hybrid methods are discussed and will highlight the perspectives on fundamental and technological advancements in AOP and AOP-based hybrid methods for PPCPs removal from wastewater. In addition, this book will portray the adverse impact of pharmaceutical compounds on environmental life, aquatic life, and human health. A detailed cost analysis of different AOP-based hybrid techniques will be examined, and it will also help formulate the guidelines to transform the wastewater treatment process from the lab scale to the pilot/industrial scale.

Metal Value Recovery from Industrial Waste Using Advanced Physiochemical Treatment Technologies focuses on the fundamental and advanced topics involved with the technologies for the extraction of metal ions from different industrial discarded volumes which may be sludge or wastewater. Uniqueness of the book lies in the fact that it covers each topic related to industrial wastes and elaborate discussions on metal ion recovery to make the readers confident about the topics and concepts explained in the section. Moreover, this book examines high potential in different downstream processes like membrane filtration, hybrid techniques, chemical leaching, electrochemical techniques, and a variety of advanced recovery techniques. Emphasis will be given to state-of-the-art concept, latest research, practical applications or commercialization through case studies, and comparative evaluation of the processes for metal ion recovery from industrial wastes.

MXenes as Emerging Modalities for Environmental and Sensing Applications: Theories, Design and Approach explores how MXene-based hybrid nanostructures are used to remedy environmental pollutants. It will also explain how they assist in sensing and degradation/removal applications to protect the ecological system both environmental and aquatic life from various types of toxic pollutants released from industrial sectors. This book focuses on the design, fabrication, and application of MXene-based nanostructures and their integration with the biotechnological processes for monitoring and treatment of pollutants in environmental matrices and sensing applications. It will also aim to increase the scientific and technological awareness of the urgency required to tackle life-threatening pollutants arising from various industrial and biotechnological sectors of the modern world.

Nutrients and Coloured Compounds in Wastewater: Advanced Treatment and Recovery reviews and highlights recent advances in nutrients and coloured compounds in terms of their treatments, recovery processes, synthesis, preparation, modifications, characterization, and performance. The book comprehensively covers topics in wastewater management including phytoremediation agents, struvite production, phosphorus recovery, advanced adsorbents, biosurfactants, and membrane technology. It provides a useful framework to help take advantage of the latest research conducted in this rapidly advancing field of wastewater treatment enabling you to develop and commercialize your own products quickly and more successfully.

Ionic Liquids in Process Intensification focuses on ionic liquids to carry out process intensification research. The book uses computational simulation methods of ionic liquids, as well as the structural design, prediction and structure regulation, to describe the process of ionic liquids intensify reaction, separation, photochemistry and materials synthesis related to chemical processes. This book analyses and discusses the latest research results and typical application cases; and provides new research ideas and methods for the correlation of different scales from molecular to chemical engineering. Ionic Liquids in Process Intensification combines computational chemistry, physical chemistry, chemical engineering, materials science and many other basic and applied disciplines.

Homogeneous Isomerization, Amination and Silicon Compounds Reactions, a volume in the Advances in Homogeneous Catalysis series, is separated into three parts to provide comprehensive coverage of isomerization, amination and silicon compounds reactions with homogeneous catalysts. The first part presents isomerization of functionalized and non-functionalized alkenes. Homogeneous amination and hydroamination reactions are investigated the second, while the final part covers homogeneous reactions of silicon compounds. The comprehensive coverage of the subject means this volume will be particularly useful to help bridge the gap between chemists and engineer's knowledge and use of homogeneous catalysis.

Homogeneous Polymerization and Oligomerization Reactions, a volume in the Advances in Homogeneous Catalysis series, covers polymerization and oligomerization reactions with homogeneous catalysts. In section one, homogeneous polymerization of alkenes, olefins, polycarbonates and Polystyrene are discussed, while the second section, presents in detail homogeneous oligomerization, cyclopolymerization, dimerization, and telomerization reactions Process reactor design, industrial applications, economic assessment and environmental challenges are discussed in depth making this volume of particular interest to academic researchers and industrialists.

Activated Carbon: Synthesis, Analysis, and Industrial Applications explores the fundamentals of activated carbon production and characterization, modification techniques and applications of machine learning in the field of activated carbon synthesis and applications. The book is divided into three parts to enable readers and researchers of all levels easy access to the information herein. Part 1 is on Synthesis methods and characterization techniques. The next six chapters on part 2 focus on diverse industrial applications of activated carbon. The last section is on machine learning applications as well as research progress in activated carbon synthesis, modification, and diverse applications. Written for researchers, graduate and undergraduate students, academics, and industry professionals in the fields of sustainable environmental science and chemical engineering, Activated Carbon: Synthesis, Analysis, and Diverse Industrial Applications will be a welcomed reference for those who wish to better understand the role of activated carbon in solving sustainability challenges in the world related to energy shortage, greenhouse gas emissions, and environmental issues.

The Sustainable Power Grid: Challenges, Applications and Case Studies provides a detailed breakdown of the different challenges faced with power grid modernization and presents a range of practical approaches to tackle these. With a strong focus on case studies and applications, the book offers extensive case study content to illustrate real-world concepts. Beginning with an overview on the evolution of the traditional power system, chapters then discuss key issues surrounding extreme weather, power quality, and power converters. The book also outlines a quantitative risk-based framework for asset health assessment of overhead lines, alongside engineering and environmental considerations. Concluding with a deep-dive into energy storage, topics consist of energy storage system protection, condition monitoring, and emerging technologies. Completely practical in nature, this is an essential resource for engineers in the electrical power industry, and offers students and researchers applied content in the latest power grid technologies.

In this issue of Surgical Pathology Clinics, guest editor Dr. Christopher J. VandenBussche brings his considerable expertise to the topic of The Current and Future Impact of Cytopathology on Patient Care. Top experts discuss how minimally invasive procedures can provide critical information to guide patient management-for example, cytopathology specimens that allow for the timely and personalized treatment of patients, reducing the number of more costly and invasive procedures. This issue focuses on the recognition of critical cytomorphologic features, current and developing options for ancillary testing, and the potential use of cytopathology specimens in precision medicine (precision cytopathology).Contains 12 relevant, practice-oriented topics including cervical HPV testing: current and future impact on patient care; lymph node fine needle aspiration: current and future impact on patient care; machine learning in cytopathology; and more.Provides in-depth clinical reviews on the current and future impact of cytopathology on patient care, offering actionable insights for clinical practice.Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Clinics in Chest Medicine, guest editors Drs. Erick Forno and Gregory Sawicki bring their considerable expertise to the topic of Pediatric Respiratory Disease. Top experts discuss COVID-19 in pediatric populations; environmental exposures and pediatric respiratory disease; genetics and genomics in childhood respiratory diseases; microbiome and metabolome: their role in pediatric respiratory disease; and more.Contains 21 relevant, practice-oriented topics including sickle cell disease and the lung; pediatric lung transplantation; health equity and advocacy in pediatric pulmonology; pediatric pulmonology in low-middle income countries; childhood interstitial lung diseases; primary cilliary dyskinesia; and more.Provides in-depth clinical reviews on pediatric respiratory disease, offering actionable insights for clinical practice.Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Psychiatric Clinics, guest editors Drs. Margie Balfour and Matthew Goldman bring their considerable expertise to the topic of Crisis Services. Crisis services are specially designed for people who need immediate, same-day access to psychiatric care. In this issue, top experts keep psychiatrists well-informed on mental health crisis intervention, including recent developments and major expansions to come.Contains 13 relevant, practice-oriented topics including equity/disparities: designing crisis services as a way to decriminalize mental illness; crisis contact centers: phone, chat and text-based crisis intervention; mass violence and crisis response; low-threshold crisis services for people experiencing homelessness and other structural barriers; and more.Provides in-depth clinical reviews on crisis services, offering actionable insights for clinical practice.Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Covering the broad range of benign and malignant disorders that affect the hematopoietic system, Hematopathology, 3rd Edition, remains your #1 source of authoritative information in this fast-changing field. Edited by Dr. Elaine Jaffe and a team of globally renowned, expert co-editors, it offers a wealth of up-to-date information in an easily accessible format, equipping you to deliver more accurate and actionable pathology reports. Comprehensive in scope, this highly illustrated, practical text is a must-have resource for residents and practicing pathologists alike.Helps you navigate the latest changes in the classification of hematolymphoid neoplasms, providing guidance for use of both the International Consensus Classification (ICC) and 5th edition of the WHO classification.Incorporates the latest molecular/cytogenetic information, regarding newly recognized entities and the latest diagnostic criteria.Provides you with today's most effective guidance in evaluating specimens from the lymph nodes, bone marrow, peripheral blood, and more, with authoritative information on the pathogenesis, clinical and pathologic diagnosis, and treatment for each.Details the latest insights on the molecular biology of benign and malignant hematologic disorders.Features more than 1,100 high-quality color images that mirror the findings you encounter in practice.Uses an easy-to-navigate, templated format with standard headings in each chapter.Includes information on disease progression and prognosis, helping you better understand the clinical implications of diagnosis.Shares the knowledge and expertise of new editors, Drs. Lisa Rimsza, Attilio Orazi, and Steven Swerdlow, providing expertise in molecular diagnostics, bone marrow and lymph node biopsies. An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date.