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Resident Stem Cells and Regenerative Therapy: Sources and Clinical Applications, Second Edition presents the main findings to date and the important factors to be considered when contemplating resident stem cells in regenerative therapies. Chapters on cardiac, brain, neural, liver, kidney, skeletal muscle, bone, pancreatic, skin and lung resident stem cells will assist in defining the level of success that has been achieved and the direction for the road ahead. With contributions from leading laboratories, open questions related to resident stem cells and regenerative therapies will also be presented for debate. In the last several decades, stem cells have greatly impacted the scientific and lay communities, providing huge advances in the treatment of devastating human diseases, including myocardial infarction, diabetes, muscular dystrophy, cystic fibrosis, cirrhosis, and osteoporosis. Alongside debates of induced pluripotent stem cells and embryonic stem cells has been the discovery of adult stem cells in many different tissues. While these organ resident or progenitor stem cells offer prospects to contribute to tissue regeneration, they also present challenges because of the complexity of organ structures.

Textile reinforcement forms (preforms) play an important role in determining the properties of the final composite and product. The preform formation process provides precise control of the fiber architecture and orientation using a suitable textile manufacturing technique. While the techniques employed for preparing glass and carbon preforms are well-known, there is still a gap in understanding on how to prepare natural preforms for composite reinforcements. Multiscale Textile Preforms and Structures for Natural Fiber Composites will bridge this gap by presenting unified knowledge on the relevant preform preparation techniques and resulting fiber architectures. Emphasis is on the structural parameters of each preform and their effect on the final composite properties. This book assembles information and knowledge on natural fiber reinforcement forms, including conventional forms, such as spun yarn, woven, knitted, nonwoven, braided, and comingled. These are illustrated and classified into one-, two-, and three-dimensional reinforcements. This book also includes information on nonconventional preform formation techniques such as unidirectional tapes, pre-impregnated preforms, spread tows, and tailored fiber placement.

Anesthesia and Analgesia in Laboratory Animals focuses on the special anesthetic, analgesic and postoperative care requirements associated with experimental interventions. Fully revised and updated, this new edition provides the reader with agents, methods and techniques for anesthesia and analgesia that ensure humane, reproducible, and successful procedural outcomes. Sections cover ethical, regulatory and scientific considerations, principles of anesthesia and analgesia, anesthetic equipment and monitoring, periprocedural care, including dedicated chapters to the assessment and management of pain in laboratory species, and practical considerations by species, including relevant anatomy, physiology, and behavior of a broad range of lab animal species. This will be a complete reference for veterinarians involved in lab animal research as well as senior graduate, graduate students, post-docs and researchers who utilize animals in biomedical research.

Electricity Cost Modeling Calculation: Regulations, Technology, and the Role of Renewable Energy, Second Edition delivers an updated view on pricing models, regulation, technology and the role renewable energy is starting to take in electricity. Starting with fundamental concepts on market structure and the increase in international regulations, the book includes cubic cost modeling cases and updated literature reviews for deeper research. Other sections cover more advanced quantitative methods such as load forecasting, updated rate designs, and the marginal cost of electricity in the United States. Includes applications will help reduce greenhouse gas emissions, thus making the reference relevant for today''s power markets. This book gives today''s engineers a practical guide on the latest techniques in electricity pricing and applications for today''s markets. Provides readers with updated, international regulations and the role of renewable energy sources Bridges the gap between foundational concepts and advanced quantitative aspects, including updated practical case studies Helps readers understand the appropriate rate/tariff structure for efficient use of electricity and renewable options

Molecular Biology, Third Edition, provides a thoroughly revised, invaluable resource for college and university students in the life sciences, medicine and related fields. This esteemed text continues to meet the needs of students and professors by offering new chapters on RNA, genome defense, and epigenetics, along with expanded coverage of RNAi, CRISPR, and more ensuring topical content for a new class of students. This volume effectively introduces basic concepts that are followed by more specific applications as the text evolves. Moreover, as part of the Academic Cell line of textbooks, this book contains research passages that shine a spotlight on current experimental work reported in Cell Press articles. These articles form the basis of case studies found in the associated online study guide that is designed to tie current topics to the scientific community. Winner of a 2020 Textbook Excellence Award (College) (Texty) from the Textbook and Academic Authors AssociationContains new chapters on non-coding RNA, genome defense, epigenetics and epigenomicsFeatures new and expanded coverage of RNAi, CRISPR, genome editing, giant viruses and proteomicsIncludes an Academic Cell Study Guide that ties all articles from the text with concurrent case studies Provides an ancillary package with flashcards, online self-quizzing, and PowerPoint slides with images

Offers a collective term for all systematic practices to minimize and control quantity and cost of energy used in providing a service. This title provides paradigms for measuring energy sustainability, pragmatic methods for applying renewable resources and efficiency improvements, and insights on managing risk in power production facilities.

By proposing innovative concepts, theorems and algorithms, this book helps to bring the cost down for both cloud users and service providers to run computation and data intensive scientific applications in the cloud. It describes several novel strategies for storing application datasets in the cloud.

Offers insights in energy efficient building from the world over, providing a multi-faceted overview of the energy efficient architecture. This title covers issues as daylighting, LED lighting, integrating renewables such as solar thermal and cooling, LEED and similar certification efforts, net-zero and close-zero structures, and more.

Biochemical Pathways and Environmental Responses in Plants: Part C, Volume 683 in the Methods in Enzymology series, highlights advances in the field. with this new volume presenting chapters on topics including Preparation of hydroxycinnamoyl-CoA thioesters using recombinant 4-coumarate:coenzyme A ligase (4CL) for characterization of BAHD acyltransferases, Near-real time determination of BAHD acyl-coA transferase reaction rates, Bioinformatic tools for protein structure prediction and for molecular docking applied to enzyme active site analysis, Computational and biochemical methods to measure the activity of carboxysomes and protein organelles in vivo, Dirigent Proteins Family Function and Structure, Three-in-One Method for High-throughput plant multi-omics, amongst other timely topics. Additional sections cover Analysis of isoprenyl-phosphates by liquid chromatography-mass spectrometry, Lignin/Lignan Biosynthesis Structure/Function, Comparison of TLC, HPLC, and direct infusion mass spectrometry methods for identification and quantification of diacylglycerol molecular species, Plant sphingolipid analysis, RNA-seq analysis of alternative pre-mRNA splicing mediated by photoreceptors in Physcomitrium patens, and much more.

Presents an introduction to the phenomena of ultra short laser pulses and describes how this technology can be used to examine problems in areas such as electromagnetism, optics, and quantum mechanics.

**Association of American Publishers (AAP) PROSE Award Finalist in Mathematics and Statistics, 2024**Probability and Statistics for Cereals and Grains: A Guide to Measurement and Analysis is a guide to help technical people be more efficient users of statistics. Author Terry C. Nelsen uses examples from his 35-plus years of experience in the field and presents the appropriate statistics and graphics to use when evaluating data. Researchers, academicians, students, technicians, processors, laboratory personnel, and those working in QA/QC will benefit from this much needed reference.

Coal and Coalbed Gas: Resilient Resource: Fueling the Future, Second Edition provides the latest research and advances, highlighting shifting trends of coal use and remaining resiliency on 'a tale of two worlds,' one half (West Europe, North America) moving away for cleaner energy sources and the other half (Asia-China-Pacific region, East Europe, South America) upping coal demand as an affordable energy source. The book emphasizes coalmine gases (CMM and AMM) as equally important as coal-fired power plants CO2 emissions as sources of potent anthropogenic greenhouse gas (GHG) prioritized for capture, use and storage and underscores R&D of emerging non-fuel uses towards coal-to-carbon-based products.Each chapter in this book is fully updated, with two new chapters covering the global occurrence of coal, the environmental impact of coal and coalbed gas use, and alternative, non-fuel uses of coal.

Breeding Disease-Resistant Horticultural Crops is a complete and comprehensive resource for understanding the concept of breeding disease resistant crops, especially horticultural crops. Breeders of horticultural crops face distinct challenges that are different from agronomy/row crops, and these crops do not benefit from the vast body of literature available for agronomic crops. This book covers the basic theories that underpin breeding for disease resistance and features extensive real-world examples. Both classical and biotechnical breeding methods are covered, with an emphasis on how these methods are adapted for horticultural species. Presented in a logical flow for the reader, this book addresses historical perspectives and context as it relates to breeding for disease resistance. It highlights treatments of resistance in the context of the phenotype, the genotype, the pathogen, the environment interaction, sources of resistance, and the deployment of resistance to obtain a durable resistance.

Bio-inoculants in Horticultural Crops, Volume Three in the Advances in Bio-inoculant series, focuses on real-time application of novel microbes that have been proven to enhance and improve plant health and productivity. The book provides comprehensive information on a range of biological approaches and mechanisms for the improvement of horticultural crops being practiced in different production systems. Covering the subject from historical developments to recent advances in microbial interventions, it addresses the potential role and bio-mechanism of bio-inoculants for challenges including stress tolerance, production, commercialization, application methodology, challenges and future roadmap for sustainable production system of horticultural crops. This volume will be useful to scientists, academicians, and students of horticulture, agriculture microbiology, plant protection, and other related subjects.

Academic Quality and Integrity in the New Higher Education Digital Environment: A Global Perspective provides discussions on the work of three editors who have significant experience in the quality assurance of teaching and learning and have been developing approaches during the recent COVID-19 pandemic. Discussions on learning and teaching during the pandemic were concentrated on how academic institutions ensure quality of courses, and that academic integrity is maintained in all assessments in a digital environment, thus ensuring what is being delivered meets global standards and professional bodies have confidence in programs delivered by the higher education sector. The area of quality assurance and academic integrity is thus critical in this new digital environment where significant educational programs will be delivered.

Geophysical Convection Dynamics, Volume Five provides a single source reference that enables researchers to go through the basics of geophysical convection. The book includes basics on the dynamics of convection, including linear stability analysis, weakly nonlinear theory, effect of rotation, and double diffusion. In addition, it includes detailed descriptions of fully developed turbulence in well-mixed boundary layers, a hypothesis of vertical homogeneity, effects of moisture, and the formation of clouds. The book focuses on the presentation of the theoretical methodologies for studying convection dynamics with an emphasis on geophysical application that is relevant to fields across the earth and environmental sciences, chemistry and engineering. Members of the Royal Meteorological Society are eligible for a 35% discount on all Developments in Weather and Climate Science series titles. See the RMetS member dashboard for the discount code.

New Insights, Trends and Challenges in the Development and Applications of Microbial Inoculants in Agriculture provides information about how to develop high-quality microbial inoculants (biofertilizers and biopesticides) for increasing crop yields and quality and reducing the economic, environmental and health costs of food production. The book's chapters discuss cutting-edge approaches and techniques to develop bioformulations as reliable, viable solutions for food production, including the importance of a legal framework to guarantee the quality and safety of these bio-products. Additionally, it provides information on the current limitations and future approaches to enhance microbial inoculant development for contributing to global food security. Interest in biofertilizers and the potential for their use in sustainable agriculture is increasing. However, many commercial bioproducts are low quality due to the lack of quality standards which causes a decrease in efficiency, high variability in the field, and loss of confidence from farmers.

Metamaterial Design and Additive Manufacturing covers optimization design, manufacturing, microstructure, mechanical properties, acoustic properties, mass-transport properties and application examples of PMs fabricated by selective laser melting additive manufacturing technology. The book introduces the definition and concept of pentamode metamaterials and then describes their characterization, including manufacturing fidelity, mechanical response, acoustic properties and so on. Final sections analyze research situations, problems and applications of additive manufacturing pentamode metamaterials.

Pharmacognosy: Fundamentals, Applications and Strategies, Second Edition represents a comprehensive compilation of the philosophical, scientific and technological aspects of contemporary pharmacognosy. The book examines the impact of the advanced techniques of pharmacognosy on improving the quality, safety and effectiveness of traditional medicines, and how pharmacokinetics and pharmacodynamics have a crucial role to play in discerning the relationships of active metabolites to bioavailability and function at the active sites, as well as the metabolism of plant constituents. Structured in seven parts, the book covers the foundational aspects of Pharmacognosy, the chemistry of plant metabolites, their effects, other sources of metabolites, crude drugs from animals, basic animal anatomy and physiology, technological applications and biotechnology, and the current trends in research. New to this edition is a chapter on plant metabolites and SARS-Cov-2, extensive updates on existing chapters and the development of a Laboratory Guide to support instructors execute practical activities on the laboratory setting.

Haschek and Rousseaux's Handbook of Toxicologic Pathology, Fourth Edition, recognized by many as the most authoritative single source of information in the field of toxicologic pathology, has been extensively updated to continue its comprehensive coverage. The fourth edition has been expanded to five separate volumes due to an explosion of information in this field requiring new and updated chapters. Completely revised with a number of new chapters, this book covers the toxicologic pathology of major classes of environmental toxicants. Volumes emphasize the comparative and correlative aspects of normal biology and toxicant-induced dysfunction, principal methods for toxicologic pathology evaluation, and major mechanisms of toxicity. This series comprises the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists, and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants. Each volume is being published separately.

The Economic and Financial Impacts of the COVID-19 Crisis Around the World: Expect the Unexpected provides an informed, research-based in-depth understanding of the COVID-19 crisis, its impacts on households, nonfinancial firms, banks, and financial market participants, and the effectiveness of the reactions of governments and policymakers in the United States and around the world. It provides reflections and perspectives on the social costs and benefits of various policies undertaken and a toolkit of preventive measures to deal with crises beyond the COVID-19 crisis. Authors Allen N. Berger, Mustafa U. Karakaplan, and Raluca A. Roman apply their expertise to the research and data on the COVID-19 economic crisis as well as draw on their own rich research experience. They take a holistic approach that compares and contrasts this crisis with other economic and financial crises and assesses economic and financial behavior and government policies in the booms before crises and the aftermaths following them, as well as the crises themselves. They do all this with a keen eye on "Expecting the Unexpected? future crises, and policies that might anticipate them and provide better outcomes for society.

Handbook of Metaheuristic Algorithms: From Fundamental Theories to Advanced Applications provides a brief introduction to metaheuristic algorithms from the ground up, including basic ideas and advanced solutions. Although readers may be able to find source code for some metaheuristic algorithms on the Internet, the coding styles and explanations are generally quite different, and thus requiring expanded knowledge between theory and implementation. This book can also help students and researchers construct an integrated perspective of metaheuristic and unsupervised algorithms for artificial intelligence research in computer science and applied engineering domains. Metaheuristic algorithms can be considered the epitome of unsupervised learning algorithms for the optimization of engineering and artificial intelligence problems, including simulated annealing (SA), tabu search (TS), genetic algorithm (GA), ant colony optimization (ACO), particle swarm optimization (PSO), differential evolution (DE), and others. Distinct from most supervised learning algorithms that need labeled data to learn and construct determination models, metaheuristic algorithms inherit characteristics of unsupervised learning algorithms used for solving complex engineering optimization problems without labeled data, just like self-learning, to find solutions to complex problems.

Autonomous Mobile Robots: Planning, Navigation, and Simulation presents detailed coverage of the domain of robotics in motion planning and associated topics in navigation. This book covers numerous base planning methods from diverse schools of learning, including deliberative planning methods, reactive planning methods, task planning methods, fusion of different methods, and cognitive architectures. It is a good resource for doing initial project work in robotics, providing an overview, methods and simulation software in one resource. For more advanced readers, it presents a variety of planning algorithms to choose from, presenting the tradeoffs between the algorithms to ascertain a good choice. Finally, the book presents fusion mechanisms to design hybrid algorithms.