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Application of Biofilms in Applied Microbiology gives a complete overview on the structure, physiology and application of biofilms produced by microbes, along with their potential application in biotechnology. Sections cover new technologies for biofilm study, physiology of microorganisms in biofilms, bacterial biofilms, biofilm development, and fungal biofilms, summarizing various technologies available for biofilm study. Subsequent chapters describe biofilm developments with Bacillus subtillis, Escherichia coli, and Pseudomonas putida, along with several chapters on the study of microbial biofilm and their advantages and disadvantages in the area of environmental biotechnology. The book closes with a chapter on the rapid development of new sequencing technologies and the use of metagenomics, thus revealing the great diversity of microbial life and enabling the emergence of a new perspective on population dynamics.

Previous edition: published as by William Menke, Joshua Menke. 2016.

The gut microbiome plays a very important role in your health. It controls digestion and has a beneficial impact on your immune system and other aspects of health. An Introduction to the Microbiome in Health and Diseases is a prelude to subsequent books on this topic which provides in-depth coverage on the microbiome from basic to clinical microbiology. This introductory volume offers an overview on the microbiome and explores the role of the human microbiome in health and disease outcomes. It examines the compositional structure and molecular approaches to microbiome characterization and identification. Additional coverage also includes an introduction to animal microbiomes, plant microbiomes, epigenetic programming, gut microbiota and the impact of diet and exercise, as well as the relationship between the microbiome and COVID-19.

Essential Oils: Extraction, Characterization and Applications covers sixteen essential oils from different herbal and aromatic plants, including production, composition and extraction techniques such as distillation, chemistry and properties, characterization and applications. The book also presents their safety, toxicity and regulation, alongside trade, storage, stability and transport concepts. Essential oils in plants, extraction and analysis, and current trends in the use of essential oils, like aroma therapy, agro-food and non-food usage are thoroughly explored. Remaining chapters are dedicated to different essential oils, including lavender, peppermint, sandalwood, citrus, eucalyptus, tea tree, clove, ginger, cinnamon, nutmeg, rosewood, juniper and pine, patchouli, clary, and more. Edited by a global team of experts in essential oils, this book is designed to be a practical tool for the many diverse professionals who develop and market essential oils.

Preceded by: Principles of gender-specific medicine: gender in the genomic era / edited by Marianne J. Legato. Third edition. [2017].

Our body is not sterile and harbors enumerable microflora that are now being understood to play a complex role in immune regulation and shaping of the immune system in a continuous and dynamic way. In 8 chapters, Microbial Crosstalk with Immune System: New Insights in Therapeutics provides an overall introduction with special focus on how the immune system which is specifically geared to get rid of non-self-antigens, allows numerous microbes to colonize the human body. In the presence of microbes there are several observations that suggest that there are multiple roles that are played by these microbes in tumor progression and shaping of our immune system which is explained at length in subsequent chapters. Microbial Crosstalk with Immune System: New Insights in Therapeutics discusses the emerging mechanisms of immune-therapeutics as well as its limitations while emphasizing the potential role of microbes in shaping immune-therapeutic and evolving novel strategies to deal with any limitations.

Prolonged microgravity exposure during long-duration spaceflight (LDSF) produces unusual physiologic and pathologic neuro-ophthalmic findings in astronauts. These microgravity-associated findings collectively define the Spaceflight Associated Neuro-ocular Syndrome (SANS). In this book, the editors compare and contrast prior published work on SANS by the National Aeronautics and Space Administration's (NASA) Space Medicine Operations Division with retrospective and prospective studies from other research groups. The book describes the possible mechanisms and potential etiologies for SANS, and provides an update and review on the clinical manifestations of SANS including: unilateral and bilateral optic disc edema, globe flattening, choroidal and retinal folds, hyperopic refractive error shifts, and focal areas of ischemic retina (i.e., cotton wool spots). The ocular imaging findings (e.g., retinal nerve fiber layer, optic disc, and choroidal changes on optical coherence tomography) of SANS is also described, including the intraorbital and intracranial findings on orbital ultrasound and magnetic resonance imaging. The knowledge gaps for in-flight and terrestrial human research including potential countermeasures for future stud is also explored, including reports on the in-flight and terrestrial human and animal research being investigated by NASA and its partners to study SANS both prospectively and longitudinally and in preparation for future long duration manned missions to space including the moon, the asteroid belt, or Mars. We think this is a unique topic and hope that NASA and its research partners continue to study SANS in preparation for future longer duration manned space missions.

3D Lung Models for Regenerating Lung Tissue is a comprehensive summary on the current state of art 3D lung models and novel techniques that can be used to regenerate lung tissue. Written by experts in the field, readers can expect to learn more about 3D lung models, novel techniques including bioprinting and advanced imaging techniques, as well as important knowledge about the complexity of the lung and its extracellular matrix composition. Structured into 15 different chapters, the book spans from the original 2D cell culture model on plastic, to advanced 3D lung models such as using human extracellular matrix protein. In addition, the last chapters cover new techniques including 3D printing, bioprinting, and artificial intelligence that can be used to drive the field forward and some future perspectives. This highly topical book with chapters on everything from the complexity of the lung and its microenvironment to cutting-edge 3D lung models, represents an exciting body of work that can be used by researchers during study design, grant writing, as teaching material, or to stay updated with the progression of the field.

Artificial Intelligence and Industry 4.0 explores recent advancements in blockchain technology and artificial intelligence (AI) as well as their crucial impacts on realizing Industry 4.0 goals. The book explores AI applications in industry including Internet of Things (IoT) and Industrial Internet of Things (IIoT) technology. Chapters explore how AI (machine learning, smart cities, healthcare, Society 5.0, etc.) have numerous potential applications in the Industry 4.0 era. This book is a useful resource for researchers and graduate students in computer science researching and developing AI and the IIoT.

Blockchain-Based Systems for a Paradigm Shift in the Energy Grid explores the technologies and tools to utilize blockchain for energy grids and assists professionals and researchers to find alternative solutions for the future of the energy sector. The focus of this globally edited book is on the application of blockchain technology and the balance between supply and demand for energy and where it is achievable. Looking at the integration of blockchain and how it will make the network resistant to any failure in sub-components, this book has very clearly explores the areas of energy sector that need in-depth study of Blockchain for expanding energy markets. Meeting the demands of energy by local trading, verifying use of green energy certificates and providing a greater understanding of smart energy grids and Blockchain use cases. Exhaustively exploring the use of Blockchain for energy, this reference useful for all those in the energy industry looking to avoid disruption in the grid and sustain and control successful flow of electricity.

Biomechanical Mapping of the Female Pelvic Floor explores new technological advances in women's healthcare intended to improve pelvic floor characterization, diagnosis and prediction of treatment outcomes. The book describes biomechanical approaches and clinical examples to demonstrate how one can evaluate the changes in the pelvic floor to gain a better understanding of an individual patient's pelvic floor dysfunctions, such as prolapse, incontinence, chronic pelvic pain, and even conditions leading to spontaneous preterm delivery and predicting maternal birth trauma. This book is a valuable resource for researchers focused on gynecology, urogynecology or obstetrics, clinicians, graduate students and biomedical scientists and bioengineers who need to better understand the technological advances in biomechanical characterization and how they can be used not only for diagnosis but also for monitoring several OBGYN-related conditions.

Promoting Responsive Feeding During Breastfeeding, Bottle-Feeding, and the Introduction to Solid Foods addresses how caregiver feeding practices and styles shape the quality and outcome of feeding interactions during infancy. Emphasis is placed on how the quality and nature of caregiver-child interactions during breastfeeding, bottle-feeding, and the introduction to solid foods shape the development of children's eating behaviors, growth trajectories and chronic disease risk. The book also considers the potential influence of broader contextual factors on early feeding interactions, including how psychological, social, cultural and economic factors may influence caregivers' abilities to implement feeding recommendations.

Every bit of information that circulates the internet across the globe is a pulse of light, that at some point will need to be converted to an electric signal in order to be processed by the electronic circuitry in our data centers, computers, and cell phones. Photodetectors (PD's) perform this conversion with ultra high speed and efficiency, in addition to being ubiquitously present in many other devices ranging from the mundane TV remote controls, to ultra high resolution instrumentation used in Laser Interferometer Gravitational Wave Observatory (LIGO) that reach the edge of the universe and measure gravitational waves. The second edition of "Photodetectors" fully updates the popular first edition with updated information covering the state-of-the-art in modern photodetectors. The 2nd edition starts with basic metrology of photodetectors and common figures-of-merit to compare various devices. It follows with chapters that discuss single-photon detection with Avalanche Photodiodes; organic photodetectors that can be inkjet printed; and silicon-germanium PDs popular in burgeoning field of Silicon Photonics. Internationally recognized experts contribute chapters on one-dimensional, nanowire, PDs as well as high speed zero-dimensional, quantum dot, versions that increase the spectral span as well as speed and sensitivity of PDs and can be produced on various substrates. Solar-blind PDs that operate in harsh environments such as deep space, or rocket engines, are reviewed and new devices in GaN technology . Novel Plasmonic PDs, as well as devices which employ micro-plasma of confined charge in order to make devices that overcome speed limitation of transfer of electronic charge, are covered in other chapters. Using different, novel technologies, CMOS compatible devices are described in two chapters, and ultra high speed PDs that use low-temperature-grown GaAs (LT-GaAs) to detect fast THz signals are reviewed in another chapter. Photodetectors used in application areas of Silicon-Photonics and Microwave-Photonics are reviewed in final chapters of this book. All chapters are of a review nature, providing a perspective of the field before concentrating on particular advancements. As such, the book should appeal to a wide audience that ranges from those with general interest in the topic, to practitioners, graduate students and experts who are interested in the state-of-the-art in photodetection.

Multifaceted Bio-sensing Technology introduces the different types of biosensors, their construction materials, configurations, production methods, and their uses in bioelectrochemical fuel cells (BEFC). It focuses on recent progress in the production of biosensing platforms/interfaces, their integration, design and fabrication, and their multifaceted applications in bioelectrochemical systems. The chapters explore the integration of genetic elements such as DNA, enzymes, and whole cells within these systems, and address environmental applications including wastewater contaminant detection, toxicity, and bioremediation. Throughout, the book shows how rapid, minuscule, and affordable biocomponents can be produced for a variety of energy and environmental applications. This book provides a practical introduction to the production of biocomponents for bioelectrochemical devices and environmental monitoring, and will be a useful reference for graduates and researchers involved in the application of bioelectrochemical systems, as well as those working more broadly in bioenergy, electrochemistry, biology, environmental engineering, and multidisciplinary research across those areas.

Mathematical Approaches to Molecular Structural Biology offers a comprehensive overview of the mathematical foundations behind the study of biomolecular structure. Initial chapters provide an introduction to the mathematics associated with the study of molecular structure, such as vector spaces and matrices, linear systems, matrix decomposition, vector calculus, probability and statistics. The book then moves on to more advanced areas of molecular structural biology based on the mathematical concepts discussed in earlier chapters. Here, key methods such as X-ray crystallography and cryo-electron microscopy are explored, in addition to biomolecular structure dynamics within the context of mathematics and physics. This book equips readers with an understanding of the fundamental principles behind structural biology, providing researchers with a strong groundwork for further investigation in both this and related fields.

Post-transcriptional Gene Regulation in Human Disease, a new volume in the Translational Epigenetics book series, offers a thorough overview and discussion of post-transcriptional genetic control mechanisms and their roles across various pathologies and human developmental outcomes, along with regulatory mechanisms targeted for therapeutic approaches. The book is broadly divided in two parts: early chapters describe the basics of post-transcriptional gene regulation, associated epigenetic mechanisms, the role of RNA binding proteins, the evolution of post-transcriptional gene regulation, and methods to study these mechanisms. The second half of the book includes deeper discussion of post-transcriptional gene regulation across specific diseases and therapeutics targets. Various post-transcriptional events, including alternative splicing and polyadenylation, mRNA stability, and miRNAs and their involvement in the disease progression, are examined in detail.

Approx.134 pages

Design, Principle and Application of Self-Assembled Nanobiomaterials in Biology and Medicine discusses recent advances in science and technology using nanoscale units that show the novel concept of combining nanotechnology with various research disciplines within both the biomedical and medicine fields. Self-assembly of molecules, macromolecules, and polymers is a fascinating strategy for the construction of various desired nanofabrication in chemistry, biology, and medicine for advanced applications. It has a number of advantages: (1) It is involving atomic-level modification of molecular structure using bond formation advanced techniques of synthetic chemistry. (2) It draws from the enormous wealth of examples in biology for the development of complex, functional structures. (3) It can incorporate biological structures directly as components in the final systems. (4) It requires that the target self-assembled structures be thermodynamically most stable with relatively defect-free and self-healing. In this book, we cover the various emerging self-assembled nanostructured objects including molecular machines, nano-cars molecular rotors, nanoparticles, nanosheets, nanotubes, nanowires, nano-flakes, nano-cubes, nano-disks, nanorings, DNA origami, transmembrane channels, and vesicles. These self-assembled materials are used for sensing, drug delivery, molecular recognition, tissue engineering energy generation, and molecular tuning.

Computational Approaches in Drug Discovery, Development and Systems Pharmacology provides detailed information on the use of computers in advancing pharmacology. Drug discovery and development is an expensive and time-consuming practice, and computer-assisted drug design (CADD) approaches are increasing in popularity in the pharmaceutical industry to accelerate the process. With the help of CADD, scientists can focus on the most capable compounds so that they can minimize the synthetic and biological testing pains. This book examines success stories of CADD in drug discovery, drug development and role of CADD in system pharmacology, additionally including a focus on the role of artificial intelligence (AI) and deep machine learning in pharmacology. Computational Approaches in Drug Discovery, Development and Systems Pharmacology will be useful to researchers and academics working in the area of CADD, pharmacology and Bioinformatics.

Smartphone Apps for Health and Wellness helps readers navigate the world of smartphone apps to direct them to those which have had the best medical evidence in obtaining the users' goal. The book covers the history of apps, how they work, and specific apps to improve health and wellness in order to improve patients outcomes. It discusses several types of apps, including apps for medical care, sleeping, relaxation, nutrition, exercise and weight loss. In addition, sections present the features of a good app to empower readers to make their own decision when evaluating which one to use. This is a valuable resource for clinicians, physicians, researchers and members of biomedical field who are interested in taking advantage of smartphone apps to improve overall health and wellness of patients.

A Complete Guidebook on Biofilm Study has emphasized the biofilm-related issues in the present context related to research and development. For this purpose, experimental design and relevant experimental protocols for the biofilm studies have been highlighted here. In addition to that, inhibitors from natural or synthetic sources against microbial biofilm development have been addressed. This approach has been further substantiated by bioinformatics as well as nanotechnology-based reports. Both, the image processing related to biofilm study and the characters of substratum associated with biofilm development have also been included for a better understanding of the beginners in this field. Further, how biofilm helps and/or hampers in food processing and waste management system, that discussion has been considered in this book. Similarly, human benefits from biofilm and reverse of it have also been included considering host-pathogen interaction, immunity aspects, and others.

Computational Intelligence Applications for Text and Sentiment Data Analysis explores the most recent advances in text information processing and data analysis technologies, specifically focusing on sentiment analysis from multifaceted data. The book investigates a wide range of challenges involved in the accurate analysis of online sentiments, including how to i) identify subjective information from text, i.e., exclusion of 'neutral' or 'factual' comments that do not carry sentiment information, ii) identify sentiment polarity, and iii) domain dependency. Spam and fake news detection, short abbreviation, sarcasm, word negation, and a lot of word ambiguity are also explored. Further chapters look at the difficult process of extracting sentiment from different multimodal information (audio, video and text), semantic concepts. In each chapter, the book's authors explore how computational intelligence (CI) techniques, such as deep learning, convolutional neural network, fuzzy and rough set, global optimizers, and hybrid machine learning techniques play an important role in solving the inherent problems of sentiment analysis applications.

Approx.346 pages

Understanding Microbial Biofilms: Fundamentals to Applications focuses on the microbial biofilms of different environments. The book provides a comprehensive overview of the fundamental aspects of microbial biofilms, their existence in nature, their significance, and the different clinical and environmental problems associated with them. The book covers both the fundamentals and applications of microbial biofilms, with chapters on the introduction to the microbial community and its architecture, physiology, mechanisms and imaging of biofilms in nature and fungal, algal, and bacillus biofilm control. In addition, the book highlights the molecular and biochemical aspects of bacterial biofilms, providing a compilation of chapters on the bacterial community and communication from different environments. Finally, the book covers recent advancements in various aspects of microbial biofilms including the chapters on their biotechnological applications. All the chapters are written by experts who have been working on different aspects of microbial biofilms.

Human Microbiome in Health and Disease, Volume 191, Part A presents updated knowledge on human microbiome as covered by renowned science faculty across the globe. Chapters in this volume include an introduction to human microbiome, Structure, functions and diversity of healthy human microbiome, Role of human microbiome in cancer, Gut microbiota and gastrointestinal cancer, Dysbiosis of human microbiome and metabolic diseases, Gut microbiome and type 2 diabetes, Gut microbiome and non-alcoholic fatty liver disease, Hepatic drug metabolism and intestinal microbiota, Emerging tools for understanding the human microbiome, and Microbiome therapeutics: Opportunity and challenges, and more. These chapters cover the composition, diversity, dynamics and functions of human microbiome in health and disease. This book will form an excellent and informative text on keystone, autochthonous, and exogenous microbiota important for human health in a simple to understand and easy to read format. Covers the structure, functions and diversity of human microbiome in health and disease Includes discussions on drug metabolisms and microbiome based therapeutics Presents emerging tools for understanding the human microbiome