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Cilia Signaling in Development and Disease, Volume 155 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Cilia and mTOR signaling, Cilia and Kidney, Extraciliary functions of IFT proteins, Cilia and eye stem cells, Cilia and eye development, Cryo-EM/ET and cilia structure, and Control of protein and lipid composition of photoreceptor outer segments and the implications for eye diseases.

Forensic Serology provides a comprehensive and complete synopsis of forensic serology. The book includes background information on different biological substances that can be detected, how the serological tests work, what the testing looks like, how to interpret the results, and what those results tell us. Coverage includes all aspects of serological testing, including basic presumptive testing, confirmatory testing, and new methods of testing, such as mRNA, methylation, proteomics, and much more. The book is written at a level that anyone with basic knowledge of science can fully understand, thus filling a gap in the market.

In this issue of Veterinary Clinics: Small Animal Practice, guest editor Dr. Joshua Stern brings his considerable expertise to the topic of Advancements in Companion Animal Cardiology. Cardiovascular disease of companion animals has seen a boom in research productivity and novel therapies that make the future of cardiac care very bright. In this issue, top experts highlight advances in diagnosis and treatment for common cardiac diseases such as hypertrophic cardiomyopathy, mitral valve degeneration, and dilated cardiomyopathy. Contains 12 relevant, practice-oriented topics including hypertrophic cardiomyopathy: advances in imaging and diagnostic strategies; the genetics of canine pulmonary valve stenosis; mitral valve repair: surgical outcomes and the rise of interventional options; the role of personalized medicine in companion animal cardiology; the role of point-of-care thoracic ultrasound in managing cardiac emergencies; and more.  Provides in-depth clinical reviews on advancements in companion animal cardiology, offering actionable insights for clinical practice.  Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Nanofluids for Large-Scale Industrial Applications examines the challenges and current progress towards large-scale industrial application of nanofluids, summarizing and bringing together varied current research strands and providing potential solutions pertaining to the scientific, economic, and social barriers that currently exist. Opening with an introduction to nanofluid synthesis, types, and properties, this book traverses the potential large-scale applications and commercialisation of nanofluids in industrial heating/cooling, solar energy systems, refrigeration systems, automotive systems, and various chemical processes and manufacturing systems. This book provides knowledge of a vast area of applications of nanofluids in industries. Thus, it also has potential to encourage and trigger the minds of researchers to discover more about nanofluids, investigate the gaps, overcome the challenges, and provide future directions for newer applications and develop nanofluids further. The book is written chiefly for graduate/postdoc level students and researchers/academics teaching or studying in chemical and thermal engineering and who are focused on heat transfer enhancement, thermal energy, nanofluids, and nano-enhanced energy systems such as solar thermal systems.

Spectroscopic Measurement: An Introduction to the Fundamentals, Second Edition contains the foundational topics associated with optical spectroscopic techniques, covering the basic theory of applied spectroscopy and presenting alternative approaches to understand physical processes. Electromagnetism, quantum mechanics, statistical mechanics, molecular spectroscopy, optics, and radiation form the foundations of the field are all thoroughly covered. On top of these rest the techniques applying the fundamentals, including Emission Spectroscopy, Laser Induced Fluorescence, and Raman Spectroscopy. This comprehensive and fully updated second edition includes additional coaching and covers new material online broadening, nonlinear techniques such as coherent anti-Stokes Raman spectroscopy, and more.Researchers not formally trained in these topics, but who apply spectroscopy in their work, will appreciate the detail contained in this book to ensure accuracy of their technique and/or to develop more sophisticated measurements.

Antimicrobial Peptides: A Roadmap for Accelerating Discovery and Development covers the most important efforts of scientists and engineers worldwide to accelerate the process of discovery, production, and eventual market penetration of more potent antimicrobial peptides. These efforts have been fueled by emerging technologies such as artificial intelligence and data science, molecular and CFD simulations, easy-to-use process simulation packages, microfluidics, 3D-printing, among many others. Such technologies can now be implemented and scaled up quickly and at relatively low cost in low-budget production facilities, critical to moving to sustainable and marketable products worldwide. Discovering novel antimicrobial peptides rationally and cost-effectively has emerged as one of the significant challenges of modern biotechnology. Thus far, this process has been tedious and costly, resulting in molecules with activities far below those needed to address the current challenge of microbial resistance to antibiotics that takes the lives of thousands of people around the world every year. Finally, the book also highlights how multidisciplinary teams have assembled to address the challenges of manufacturing, biological testing, and clinical trials to finally reach complete translation.

3-Membered Heterocycle Synthesis provides readers with detailed information about the synthesis of three-membered heterocyclic compounds. The book comprehensively describes three-membered heterocyclic compounds synthesis, allowing the audience to quickly assess possible synthetic approaches. Other sections discuss their unusual combination of synthetic flexibility, reactivity, and atom economy. The main challenge for synthetic chemists, both in academia and industry, is the search for efficient approaches to target molecules. This book presents several methodologies for the synthesis of three-membered heterocyclic compounds.

Agroforestry for Carbon and Ecosystem Management is a comprehensive overview of current research, issues, challenges, and case studies in the area of agroforestry. The book focuses specifically on carbon source-sink relationship and management through agroforestry practices with a goal of improving overall environmental sustainability. Through expert insights and case studies, the book promotes carbon management, greenhouse gas emission reduction, forest, and ecosystem services management, along with relevant sustainable approaches for natural resources conservation. Users will find insights into novel approaches for natural resource management, with specific attention given to technologies related to carbon capture and management. In addition, the book addresses the knowledge gap in relation to agroforestry, sustainability, and agroecosystem management and explores the application of remote sensing and geospatial technologies for agroforestry management.

Practical Design and Applications of Medical Devices focuses on devices which receive and transmit bioelectric signals, such as electrocardiograph, electrodes, blood flow, blood pressure, physiological effects and, in some cases, current flowing through the human body. This thorough guide for researchers and engineers in the field of biomedical and instrumentation engineering presents a streamlined medical strategy for designing these medical devices, sensors, and tools. It also promotes operational efficiency in the healthcare industry, with the goals of improving patient safety, lowering overall healthcare costs, broadening access to healthcare services, and improving accessibility.

Computational Intelligence and Modelling Techniques for Disease Detection in Mammogram Images comprehensively examines the wide range of AI-based mammogram analysis methods for medical applications. Beginning with an introductory overview of mammogram data analysis, the book covers the current technologies such as ultrasound, molecular breast imaging (MBI), magnetic resonance (MR), and Positron Emission mammography (PEM), as well as the recent advancements in 3D breast tomosynthesis and 4D mammogram. Deep learning models are presented in each chapter to show how they can assist in the efficient processing of breast images. The book also discusses hybrid intelligence approaches for early-stage detection and the use of machine learning classifiers for cancer detection, staging and density assessment in order to develop a proper treatment plan. This book will not only aid computer scientists and medical practitioners in developing a real-time AI based mammogram analysis system, but also addresses the issues and challenges with the current processing methods which are not conducive for real-time applications.

The Water-Energy-Food Nexus: Optimization Models for Decision Making, Volume 32 covers water, energy, and food as crucial resources for human well-being and sustainable development. These resources are inextricably interrelated, therefore, to cover water, energy, and food demands in different sectors and at different scales, it must be considered several sources to produce resources, and the interlinkages of resources for a proper integration must be considered. This book emphasizes issues that must be considered in the design of water-energy-food nexus systems, such as the selection of technologies to produce water or energy, size of technologies, and food required for nutritional demands.In addition, mathematical models are presented for the design of water-energy-food nexus systems involving several strategies to account for issues such as sustainable development, security of resources, interest in conflicts from stakeholders, and efficient allocation of resources.

Impressive engineering advances have occurred that can curb the impact of seismic events on residential properties, commercial edifices, architectural heritage, and infrastructure. Written by a university professor with decades of on-site experience, Construction of Earthquake-Resistant Concrete and Steel Structures offers up-to-date information and technical competence with the aim of supporting an understanding of fundamental concepts for concrete and steel structures, shell elements, and reinforcement detailing. The volume is an invaluable resource for students, researchers, and early-career practicing professionals to also learn about construction issues and how to solve practical challenges while ensuring that building codes (ACI, AISC, ANSI, ASCE, RCSC, and many more) and design standards' requirements are upheld.

In this issue of Neurologic Clinics, guest editosr Drs. David L. Perez and Sara A. Finkelstein bring their considerable expertise to the topic of Functional Neurologic Disorders. Top experts in the field cover issues such as functional movement disorder: assessment and treatment; functional cognitive disorder: diagnosis, treatment, and differentiation from secondary causes of cognitive dysfunction; functional speech and voice disorders: diagnosis and treatment; personalizing clinical care in functional neurological disorder: a biopsychosocial-informed perspective; and more.In this issue of Neurologic Clinics, guest editosr Drs. David L. Perez and Sara A. Finkelstein bring their considerable expertise to the topic of Functional Neurologic Disorders. Top experts in the field cover issues such as functional movement disorder: assessment and treatment; functional cognitive disorder: diagnosis, treatment, and differentiation from secondary causes of cognitive dysfunction; functional speech and voice disorders: diagnosis and treatment; personalizing clinical care in functional neurological disorder: a biopsychosocial-informed perspective; and more.

Offering practical tips and expert answers to topics in dentistry, oral medicine, and patient management, Dental Secrets, 5th Edition serves as an ideal preparation tool for exams, clinical rotations, and board certification. A concise, illustrated Q&A format covers key areas such as oral pathology, radiology, periodontology, endodontics, restorative dentistry, prosthodontics, orthodontics, infection control, and oral and maxillofacial surgery. This mini reference makes it easier to prepare for real-world clinical scenarios and review for the INBDE and other certification exams! Dentistry's best "secrets" are shared by experts specializing in various areas of dentistry and oral medicine. Concise answers to more than 2,000 questions in dentistry and oral medicine provide valuable pearls, tips, memory aids, and "secrets" in an easy-to-read, numbered format. More than 100 illustrations, tables, and boxes highlight key takeaways. NEW! Brand-new chapter reveals "secrets" surrounding orofacial pain. NEW! Questions and examples are prepared with the new INDBE exam content in mind. NEW! A new group of contributing authors and a new co-editor - all leaders in the field of dentistry - bring a fresh perspective and valuable expertise to the text. NEW! An enhanced eBook, included with print purchase, provides access to all the text, figures, and references, plus the ability to search, customize content, make notes and highlights, and have content read aloud. UPDATED! Fresh revisions with the most current clinical information keep students, practitioners, and those preparing for recertification up to date on key advances in the practice of dentistry.

"Available to Pharmacy Technicians with at least three years of work experience, the Advanced Certified Pharmacy Technician (CPhT-Adv) credential provides a pathway for obtaining higher-level skills and advancing your career. This new resource gives you the review and practice you need to prepare for the exam with an easy-to-use format, sample certification exams, content review chapters, and more."--

The immune system is highly complex, it senses foreign invaders, thus protecting the body. The adaptive arm of the immune system confers long-term protection, whereas the innate immune system confers immediate protection. In the case of the immune system, the pattern recognition receptors offer various modes of sensing the molecular patterns associated with pathogens. Toll-like receptors (TLRs) are important mediators of inflammatory pathways in the gut which play a major role in mediating the immune responses towards a wide variety of pathogen-derived ligands and link adaptive immunity with the innate immunity. This book covers the role of TLRs in several vector-borne Diseases. Starting with an introduction to these diseases, the book explains the different types of receptors involved in these diseases. The diseases are then covered in separate chapters, including: malaria, lymphatic filariasis, visceral leishmaniasis, dengue fever, chikungunya, West Nile fever, and Japanese encephalitis. The book is a handy reference for researchers and trainees involved in clinical medicine and infection control. It can also serve as supplementary reading material for Students undertaking courses in biotechnology, public health, entomology, immunology, epidemiology, and life sciences.

Mineral Systems, Earth Evolution, and Global Metallogeny provides insights into the critical parameters of Earth's evolution, particularly in terms of thermal state, tectonics, and the atmosphere-hydrosphere-biosphere system that control the metallogeny of the planet. World-class to giant mineral systems are described and interpreted in terms of their relationship to critical periods of change in tectonic regimes within the supercontinent cycle and evolution of the mantle lithosphere. Specific times of formation of highly anomalous giant mineral systems, such as the so-called Boring Billion, are discussed together with specific tectonic environments, such as craton edges and thick lithosphere margins. This book provides an overview on how the evolution of Earth has dictated the nature and distribution of its mineral resources that are the foundation of our modern industries and provides insights into critical parameters for conceptual exploration targeting. Mineral Systems, Earth Evolution, and Global Metallogeny provides a helpful resource for researchers, academicians, undergraduate and graduate students, and geologists engaged in the fields of economic geology, geologic exploration, mineral systems, and earth evolution in understanding the timing and distribution of the world's major mineral deposits and their relation to critical parameters controlling earth's evolution.

Environmental Analytical Chemistry investigates how to use modern scientific theory and advanced experimental techniques to identify and determine the types, components, amounts, and chemical forms of substances in the environment, including both naturally occurring chemicals and anthropogenic contaminants. The book covers the newest developments of environmental analytical chemistry, including discussions of pretreatment techniques of environmental samples, chemical species and speciation analysis, atmospheric pollutants analysis, water pollutants analysis, soil pollutants analysis, sensing techniques for environmental pollutants and on-site rapid emergency analytical technology for environmental emergencies.The book will be of use to researchers and technical personnel in the fields of environmental science, environmental chemistry, environmental monitoring, and analytical chemistry.

Revolution in the Seas: Ending Overfishing and Building Pesco-ecology, Sustainable Agro-Ecology of Fishing provides an in-depth analysis of the dynamics between humans and disrupting marine ecosystems by extracting its wild animals. It highlights practical changes that can be implemented to prevent overfishing and create a new way of fishing, the pescoecology that benefits marine life, coastal communities, and human consumers alike. Written by a leader in fisheries science and conservation, this book begins by diagnosing the issue of overexploitation, showing the dynamics and consequences on living marine resources and ecosystems. It then goes on to demonstrate how recent scientific discoveries, including tropic network functionality, are changing humans' approach to fishing sustainably. The final sections are devoted to ecological, economic, and social solutions. Revolution in the Seas is a vital resource for fisheries scientists, managers, academics and students in marine biology or fisheries studies. All stakeholders and citizens involved in building a sustainable relationship between humans and the sea will also benefit from this book's revolutionary content.

Designing Advanced Respiratory Protective Devices for Pandemics: Performance, Mechanism and Future Perspectives identifies emerging and critical issues that directly or indirectly influence the protective performance of Respiratory Protective Devices (RPDs), along with important future research directions. The severity of the COVID-19 pandemic emphasizes the vital role of respiratory protection provided by PPE (and RPD) in novel infectious respiratory disease control. A wealth of recent research on coronavirus mitigation measures is combined with prior information on infectious diseases, RPDs, and human physiological and psychological responses to make this a fundamental resource on recent advances, innovative perspectives on respiratory protection, and new applications. The effectiveness of such disease control measures rely greatly on the performance of the RPD, user compliance, and proper use. Only an interdisciplinary approach to this issue can lead to success.

Dr. Richard Polin's Neonatology Questions and Controversies series highlights the toughest challenges facing physicians and care providers in clinical practice, offering trustworthy guidance on up-to-date diagnostic and treatment options in the field. In each volume, renowned experts address the clinical problems of greatest concern to today's practitioners, helping you handle difficult practice issues and provide optimal, evidence-based care to every patient.The thoroughly updated, full-color, 4th Edition of Neonatal Hemodynamics:  Provides in-depth clinical overviews of the many hemodynamic conditions that are relevant for the neonatologist, offering guidance based on the most up-to-date understanding of underlying pathophysiology.  Places emphasis on controversial areas that can entail different approaches.  Features the most current clinical information throughout, covering everything from basic cardiovascular physiology to advanced monitoring and hemodynamic assessment. Several chapters have been revised to focus on the novel concepts of hemodynamic phenotypes, enhanced diagnostic precision, and phenotypic profiling, and are illustrated by demonstrative case presentations.  Includes new chapters on neonatal hemodynamic pharmacology, hemodynamic management in special circumstances (twin-twin transfusion, infant of a diabetic mother, arteriovenous malformations), neonatal hemodynamic care in the resource-challenged country, chronic pulmonary hypertension assessment and management, and more.   Utilizes a consistent chapter organization to help you find information quickly and easily, and contains numerous charts, graphs, radiographic images, and photographs throughout.  Offers the most authoritative advice available from world-class neonatologists with expertise in neonatal hemodynamics, who share their knowledge of new trends and developments in neonatal care.  An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.  Purchase each volume individually, or get the entire 7-volume Neonatology Questions and Controversies set, which includes online access that allows you to search across all titles!  Gastroenterology and Nutrition  Hematology and Transfusion Medicine  Neonatal Hemodynamics  Infectious Disease, Immunology, and Pharmacology  Renal, Fluid, and Electrolyte Disorders  Neurology  The Newborn Lung

Metal-Chalcogenide Nanocomposites: Fundamentals, Properties, and Industrial Applications focuses on metal chalcogenide nanomaterials for environmental remediation and corrosion applications. The book's chapters focus on cost-effective and facile fabrication approaches, their growth mechanisms, optical, electrical, and other important properties, and their applications in a broad range of diverse fields such as photocatalysis, photovoltaics, hydrogen production, lithium batteries, energy storage, anticorrosion, and sensor devices. The book will be an important information source for both material scientists and engineers who want to create the next generation of products and devices for energy and environmental applications.

Interpretable Machine Learning for the Analysis, Design, Assessment, and Informed Decision Making for Civil Infrastructure highlights the growing trend of fostering machine learning to realize contemporary, smart, and safe infrastructure. This volume delves into the latest advancements in machine learning and artificial intelligence, providing readers with practical insights into their applications in the analysis, design, and assessment of civil infrastructure. From the innovative use of Generative Adversarial Networks in the design of shear wall structures to the application of deep learning for damage inspection of concrete structures, each chapter offers a unique perspective on the integration of cutting-edge technology in the field. Explore the potential of AI-driven fire safety design for smart buildings, the challenges and promises of large-scale evacuation modeling, and the use of machine learning classifiers for evaluating liquefaction potential. The book also features an in-depth discussion on explainable machine learning models for predicting the axial capacity of strengthened CFST columns and the development of spalling detection techniques using deep learning. Whether you are a civil engineer, researcher, or industry professional, this book is an invaluable resource that will equip you with the knowledge and tools to revolutionize civil infrastructure design and management. This book presents innovative research results supplemented with case studies from leading researchers in this dynamic and emerging field to be used as benchmarks to carry out future experiments and/or facilitate the development of future experiments and advanced numerical models. The book is delivered as a guide for a wide audience, including senior postgraduate students, academic and industrial researchers, materials scientists, and practicing engineers working in civil, environmental, and mechanical engineering.

Progress in Heterocyclic Chemistry (PHC), Volume 35 is the latest in this annual review series that contains both highlights of the previous year's literature on heterocyclic chemistry and articles on new and developing topics of particular interest to heterocyclic chemists. Chapters in this new release are all written by leading researchers in their field, constituting a systematic survey of the important original material reported in the literature of heterocyclic chemistry in 2021. As with previous volumes in the series, this book will enable academic and industrial chemists, and advanced students, to keep abreast of developments in heterocyclic chemistry.

Industrial Applications of Biosurfactants and Microorganisms Green Technology Avenues from Lab to Commercialization covers a variety of current biosurfactant research advancements and progresses, providing insights into the most recent academic advances, major applications, and implementation studies from across the world. The book focuses entirely within the scope of biochemistry and biotechnology research and demonstrates the application of biosurfactants in cell mobility, cell communication, nutrient acquisition, and plant and animal disease. Biosurfactants have antibacterial, antifungal, and antiviral properties, as well as adhesive properties and are used in vaccinations, gene therapy, and the enhancement of microbial biocontrol systems. This book is designed for a broad audience working in the fields of biochemistry, surface science, colloid and interface science, and is an invaluable reference for university libraries and industrial institutions, government and independent institutes, individual research groups, and scientists working in the field of surface science systems.

Advances in Digitalization and Machine Learning for Integrated Building-Transportation Energy Systems examines the combined impact of buildings and transportation systems on energy demand and use. With a strong focus on AI and machine learning approaches, the book comprehensively discusses each part of the energy lifecycle, considering source, grid, demand, storage, and usage. Opening with an introduction to smart buildings and intelligent transportation systems, the book presents the fundamentals of AI and its application in renewable energy sources, alongside the latest technological advances. Other topics presented include building occupants' behavior and vehicle driving schedule with demand prediction and analysis, hybrid energy storages in buildings with AI, smart grid with energy digitalization, and prosumer-based P2P energy trading. The book concludes with discussions on blockchain technologies, IoT in smart grid operation, and the application of big data and cloud computing in integrated smart building-transportation energy systems. This title provides critical information to students, researchers, and engineers wanting to understand, design, and implement flexible energy systems to meet the rising demand in electricity.

Water Resources Systems Planning and Management, Second Edition, Volume 51 presents new and updated material, including case studies, examples and important updates on topics such as climate change and integrated water resources management. Authored by two renowned experts in the field of water resources, this text provides an overview of the current status of water resources utilization, the likely scenario of future demands, simulation and techniques of economic analysis, concepts of planning, the planning process, integrated planning, public involvement, reservoir sizing, and finally, systems operation and management. This book presents a comprehensive overview of the field that is relevant for students, professors, scholars, researchers, and consultants in the fields of Water Resources, Civil Engineering, Environmental Engineering and Hydrology.

The Kirkwood-Buff Theory of Solutions: With Selected Applications to Solvation and Proteins presents the Kirkwood-Buff (KB) Theory of solution in a simple and didactic manner, making it understandable to those with minimal background in thermodynamics. Aside from the fact that the KB Theory may be the most important and useful theory of solutions, it is also the most general theory that can be applied to all possible solutions, including aqueous solutions of proteins and nucleic acids. Introductory chapters give readers grounding in the necessary chemical thermodynamics and statistical mechanics, but then move to a systematic derivation of Kirkwood-Buff theory and its inversion. Originally published in 1951, the KB theory was dormant for over 20 years. It became extremely useful after the publication of the "Inversion of the KB theory" by the author Arieh Ben-Naim in 1978. The book explains all necessary concepts in statistical mechanics featured in the theory in a simple and intuitive way. Researchers will find the theory useful in solving any problem in mixtures or solutions in any phase. Some examples of applications of the KB theory, to water, aqueous solutions, protein folding, and self-association of proteins, are provided in the book.

Metal-organic Frameworks in Analytical Sample Preparation and Sensing presents all the areas of applications of metal-organic frameworks in analytical sample preparation. Metal-organic frameworks are crystalline coordination polymers with robust and stable crystal structures, high synthetic tunability, and interesting properties for their use in analytical applications, including their detailed use as sorbents in miniaturized-extraction procedures and as components in sensors. This book also provides important information about the synthesis and characterization of these materials, with useful tips written by experts on the subject with respect to their conditioning, handling, and recycling. Their outstanding properties, adsorptive capabilities, and structural diversity are also highlighted. This will help experts in the field to select the proper metal-organic framework for a particular analytical application.