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Small Lungs and Obstructed Airways: Reassessing Chronic Obstructive Pulmonary Disease proposes an alternative perspective to current explanations for the distribution of chronic lung disease. The book considers the link between chronic respiratory disease and associated mortality with smaller lungs rather than obstructed airways and explores other factors contributing to poor lung health besides the current emphasis on the roles of air pollution, occupational exposures, and cardio-metabolic disease. It presents the findings of the Burden of Obstructive Lung Disease (BOLD) study, sharing new views on the prevalence of obstructive lung disease and risk factors across various global regions. Sections cover decreased lung function, including the prevalent views on the impact of both household and external air pollution, occupational exposure, and the prenatal and postnatal/childhood environment in the etiology of impaired lung function and COPD. The book then moves on to discussions on the impact poverty and nutrition has on lung health, sharing the findings of the BOLD study regarding its effect on lung function and risk of COPD in lower-income countries. The book closes with a chapter outlining the clinical and public health implications of the findings discussed in the book.

Severe accidents in Sodium Fast Reactors: Safety Study Approach, Prevention and Mitigation by Design is a unique presentation of research work from the Sodium Fast Reactor Severe Accident team at CEA. Focusing on in-core and out-core severe accident phenomena, this book analyzes severe accident scenarios and mitigation, related calculations and tools, and key outcomes from important experimental programs. The book describes the state-of-the-art on severe accident research which will help to inform and direct further pre-conceptual Generation IV SFRs. Lessons learned from the pre-conceptual phase of the French ASTRID project are highlighted alongside different approaches to demonstrate robustness.To support the demonstration of concepts explored, a special section dedicated to calculation tools and their validation offers readers a unique set of tools to guide and inform their own research work. Readers will gain a deep understanding of methodologies to illustrate approaches as well as an overview of safety approaches from key countries based on the editor's rich international collaboration.

Interstellar Travel: After Arrival is a comprehensive, technical look at the necessary considerations for settlement on an extra solar planet following interstellar travel, addressed by leading experts in the fields of space development. The book features the current and future plans for lunar, Mars, and asteroid settlement, and how what we learn from such future endeavors might apply to settlement at destinations around other stars. In addition, scientists who have been considering the construction of large space structures and terraforming discuss realistic options to be considered, along with chapters covering necessary considerations such as whether terraforming is possible and how it might be accomplished, the ethical issues and scientific constraints to interacting with an alien biosphere, and what we might learn from settling within our own Solar System that would apply to settling elsewhere.The third book of a three-book compilation, Interstellar Travel: After Arrival offers in-depth, up-to-date and realistic technical and scientific considerations of the challenges that settling on an exoplanet would bring, including review of the current technological capabilities and how they might be put towards life on an extra solar planet.

Materials for Electronics Security and Assurance reviews the properties of materials that could enable devices that are resistant to tampering and manipulation. The book discusses recent advances in materials synthesis and characterization techniques for security applications. Topics addressed include anti-reverse engineering, detection, prevention, track and trace, fingerprinting, obfuscation, and how materials could enable these security solutions. The book introduces opportunities and challenges and provides a clear direction of the requirements for material-based solutions to address electronics security challenges. It is suitable for materials scientists and engineers who seek to enable future research directions, current computer and hardware security engineers who want to enable materials selection, and as a way to inspire cross-collaboration between both communities.

Structural Health Monitoring/Management (SHM) in Aerospace Structures provides readers with the spectacular progress that has taken place over the last twenty years with respect to the area of Structural Health Monitoring (SHM) Management. The SHM field encompasses transdisciplinary areas, including smart materials, sensors and actuators, damage diagnosis and prognosis, signal and image processing algorithms, wireless intelligent sensing, data fusion, and energy harvesting. This book focuses on how SHM techniques can be applied to aircraft, mechanical and civil engineering structures with particular emphasis on composite materials. This will be a valuable reference resource for R&D managers, materials scientists, and engineers working in the aerospace sector, for researchers and system designers working in industry, and for academia and government research agencies developing new systems for the SHM of aerospace, mechanical, and civil engineering structures.

Improving and Tailoring Enzymes for Food Quality and Functionality, Second Edition covers the most relevant information demanded in the production, engineering, and application of enzymes. The title is very detailed and an important cross-discipline resource that merges academia and industry. This totally revised new edition covers a broad range of topics related to enzymes and their use in food, presenting both the fundamental theory and practical application, updated with interesting novel information on biosensors, waste, valorization, up-cycling and engineering perspectives, besides an increased focus on sustainability.

Design, Characterization and Fabrication of Polymer Scaffolds for Tissue Engineering covers core elements of scaffold design, from properties and characterization of polymeric scaffolds to fabrication techniques and the structure-property relationship. Particular attention is given to the cell-scaffold interaction at the molecular level, helping the reader understand and adapt scaffold design to improve biocompatibility and function. The book goes on to discuss a range of tissue engineering applications for polymeric scaffolds, including bone, nerve, cardiac and fibroblast tissue engineering. This is an important, interdisciplinary work of relevance to materials scientists, polymer scientists, biomedical engineers, and those working regenerative medicine.

Amongst thermoplastic biodegradable polymers, polylactic acid (PLA) has been widely used in many different applications but it still has limited use in various industrial sectors such as medical, packaging, textile, water, and wastewater treatment. To increase the use of these materials more information is needed on their properties, characterization, processing, safety, and sustainability. Natural Fibre-Reinforced PLA Composites: Processing, Characterization and Applications reviews the thermal, physico-chemical, fire retardant, mechanical, tribological, biodegradable and anti-microbial properties of these materials. Fabrication of PLA biocomposites using advanced fabrication techniques like additive manufacturing and electrospinning are also discussed in detail. The book will be a valuable reference for academic and industrial researchers, materials scientists and engineers working in the development of polymers, bioplastics, polymer composites and biocomposites as well as industrial manufacturers.

Fractional Difference, Differential Equations, and Inclusions: Analysis and Stability is devoted to the existence and stability (Ulam-Hyers-Rassias stability and asymptotic stability) of solutions for several classes of functional fractional difference equations and inclusions. Covered equations include delay effects of finite, infinite, or state-dependent nature, and tools used to establish the existence results for the proposed problems include fixed point theorems, densifiability techniques, monotone iterative technique, notions of Ulam stability, attractivity and the measure of non-compactness, as well as the measure of weak noncompactness. The tools of fractional calculus are found to be of great utility in improving the mathematical modeling of many natural phenomena and processes occurring in the areas of engineering, social, natural, and biomedical sciences. All abstract results in the book are illustrated by examples in applied mathematics, engineering, biomedical, and other applied sciences.

Bioconjugated Materials Part 2, Volume 103 in the Comprehensive Analytical Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters on bioconjugated materials. Each chapter is written by an international board of authors.

Soft Particles, Volume 62 in the Advances in Chemical Engineering series, highlights advances in the field, with this new volume covering an Introduction to soft particles: state-of-the-art and perspectives, Synthesis of microgels and nanogels via covalent cross-linking strategies, Design and modelling of sub-micron particles via innovative precipitation and self-assembly, Smart functionalization of polymers and particles: an overview of the chemical strategies, Nanomechanical properties of soft particles, Dynamics and rheology of soft particles, Degradable aqueous polymer dispersions, Food-biopolymers for nanogel fabrication, Nanoparticles, nanofibrils and tissues in cosmetic dermatology, Advanced approaches in cancer therapy via administration of polymer-based particles, and more.

Inherently Safer Design, Volume Seven in this ongoing series, highlights new advances in chemical engineering, with interesting chapters that provide an Introduction to Inherently Safer Design (ISD), ISD Fundamentals, History of ISD, ISD Life Cycle Considerations, ISD Indices, ISD and Human Factors, Conceptual and Practical Applications of ISD, Challenges to ISD Application, ISD Regulatory Requirements, ISD Case Studies, Risk-based ISD, ISD and Digitalization. ISD and Inherently Safer Operation (ISO), and the Future of ISD.

International Review of Research in Developmental Disabilities, Volume 64 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

Annual Reports on NMR Spectroscopy, Volume 110, presents the latest release in a series that has established itself as a premier resource for both specialists and non-specialists interested in new techniques and applications pertaining to NMR spectroscopy.

Advances in Virus Research, Volume 117, the latest release in a series that highlights new advances in the field, includes invaluable updates written by an international board of authors. Chapters in this new release include Pathogenesis of neuroinvasive flaviviruses, Cellular entry and egress of astroviruses, Rift Valley Fever virus entry and infection, and more.

Advances in Physical Organic Chemistry, Volume 57 presents the latest reviews of recent work in physical organic chemistry, providing a valuable source of information that is ideal not only for physical organic chemists applying their expertise to both novel and traditional problems, but also for non-specialists across diverse areas who identify a physical organic component in their approach to research. The book's hallmark is its quantitative, molecular level understanding of phenomena across a diverse range of disciplines.

Advances in Heat Transfer, Volume 56, presents the latest in a serial that highlights new advances in the field, with this updated volume presenting interesting chapters written by an international board of authors.

Advances in Food Security and Sustainability, Volume Eight highlights new advances in the field with this new volume presenting interesting chapter on important topics such as Food Security, Diversification, and Inequality: Indonesia in the Era of Economic Recovery and High Price Trends, Oil Palm Cultivation and the Impact of Climate Change in Malaysia: A Systematic Review, Food Loss and Waste in Nigeria: Implications for Food Security and Environmental Sustainability, and the Role of different stakeholders and their relative importance in managing disaster.

Advances in Food and Nutrition Research provides updated knowledge about nutrients in foods and how to avoid their deficiency, especially for those essential nutrients that should be present in the diet to reduce disease risk and optimise health. The series provides the latest advances on the identification and characterisation of emerging bioactive compounds with putative health benefits, as well as up-to-date information on food science, including raw materials, production, processing, distribution and consumption, always having in mind its nutritional benefits and health effects. Contains contributions that have been carefully selected based on their vast experience and expertise on the subject Includes updated, in-depth, and critical discussions of available information, giving the reader a unique opportunity to learn Encompasses a broad view of the topics at hand

Advances in Clinical Chemistry, Volume 117, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists.

The Biology of Ageing: From Hallmarks to Drugs provides a series of reviews covering multiple aspects of the translational pipeline as interventions in the biology of ageing itself become a clinical reality. New chapters cover Cellular senescence and NAD+: what are the links?, Biomarker for ageing: potential and pitfalls, What chemists offer to ageing research, You are what you eat - or are you? Exploring dietary versus topical anti-oxidants in skin ageing, Clinical trials: A simple guide for gerontologists, Towards an ethical framework for geroscience, and more. The book explores links between known ageing mechanisms and new interventions, agents and actions at the nutraceutical-drug divide, the challenges and opportunities provided by biomarkers and chemistry- biology interface and lastly the ethical and operational challenges of clinical trials in the age of translational geroscience.

Biocatalysis in Asymmetric Synthesis, a new volume in the Foundations and Frontiers of Enzymology series, offers an applied discussion on synthesizing biological catalysts using asymmetric synthesis for varying applications. Here, global experts in the field analyze a wide variety of biocatalysts and their physical states, process conditions for their asymmetric synthesis, solvents required during synthesis, and even downstream procedures for the recovery of final products. The book adopts an interdisciplinary approach, merging fundamental biology and its synthetic applications across industries with a wide range of practical examples, from directed evolution to biotransformation and production of novel enzymes and non-conventional catalysts. Throughout the book, the impact and application of biocatalysis in sustainable processing is considered in-depth. This book will also help non-experts in biocatalysis to apply this knowledge in their own research, providing a thorough overview of the ways asymmetric biocatalytic approaches may be adapted for different disciplines and downstream products.

Nutrition in the Control of Inflammation: Emerging Roles for the Microbiome and Epigenome offers a comprehensive overview on how our diet promotes or attenuates inflammation to regulate inflammatory diseases. Broken into five sections, this book presents an introduction to the microbiome and epigenome in nutrition, subsequently covering diet, lifestyle, and the microbiome in the development of inflammatory diseases, nutrition and the epigenome in metabolic and cardiovascular diseases, diet, epigenetics, and microbiome. This book also addresses health-disparities in diet, epigenetics, and gut microbes. It will be of interest to nutrition researchers, nutritionists, and postgraduate students, as well as others working in, studying, and researching related fields.

Application of Emerging Technologies and Strategies to Extract Bioactive Compounds, Volume Three in the Developments in Food Quality and Safety series, is the most up-to-date resource covering trend topics such as advances in the analysis of toxic compounds and control of food poisoning, food fraud, traceability and authenticity, revalorization of agrifood industry, natural antimicrobial compounds and application to improve the preservation of food, non-thermal processing technologies in the food industry, nanotechnology in food production, and Intelligent packaging and sensors for food applications. Chapters in this release explore the latest developments in the application of each technology, such as ultrasound, microwave, high-pressure, pulsed electric fields, ohmic, uv and ir heating, extrusion, and solar energy assisted extractions, along with membrane technologies and alternative solvents for green extraction. The series is edited by Dr. José Manuel Lorenzo and authored by a team of global experts in the field.

Probability and Statistics for Physical Sciences, Second Edition is an accessible guide to commonly used concepts and methods in statistical analysis used in the physical sciences. This brief yet systematic introduction explains the origin of key techniques, providing mathematical background and useful formulas. The text does not assume any background in statistics and is appropriate for a wide-variety of readers, from first-year undergraduate students to working scientists across many disciplines.

Improving Stress Resilience in Plants: Physiological and Biochemical Basis and Utilization in Breeding addresses the urgent need for improved understanding of major plant stress tolerance mechanisms, the identification of the genes, and gene products that are key to improving those mechanisms and means of optimizing those genes through molecular approaches. With a focus on plant physiological and biochemical attributes at both cellular and whole plant levels, this book includes the latest information on crosstalk between the various signaling molecules and quantitative trait locus (QTL). Further, it explores the extension of these mechanisms to breeding approaches, confirming overall understanding and inspiring further research. Written by a team of global experts, and presented in three thematic sections, the book provides insights into physical adaptations, metabolism and pathways, and breeding techniques including CRISPR and conventional approaches to reduce the negative effects of stresses and improve crop yield even under stress conditions. It is an ideal resource for researchers, academics and advanced students seeking to improve stress tolerance among crop plants and developing key future strategies for sustainable food production.

Ion Channels in Cancer, Volume 92 in the Current Topics in Membranes series, highlights advances in the field, including chapters on the Interplay of calcium and potassium signals in cell cycle and cancer, Non-conducting functions of ion channels in cancer and neurological disease, Sodium channels and progression of solid tumors, The Elusive Nav1.7: From Pain to Cancer, Signaling Pathways in cancer: Channels Interactome as a novel therapeutic target, Ion channels in cancer drugs resistance, CLIC1: A potential therapeutic target for malignant glioma, Beyond the Building Blocks: Amino Acids as modulators of ion channels and transporters, and Activation of potassium channels unveils tumor vulnerability.

Transfer Printing Technologies and Applications is a complete guide to transfer printing techniques and their cutting-edge applications. Sections in the book explore the fundamentals behind these technologies, along with state-of-the-art applications enabled by transfer printing techniques, including areas such as flexible sensors, flexible transistors, wearable devices, thin film-based energy systems, flexible displays, microLED-based displays, metal films, and more. A concluding chapter addresses current challenges and future opportunities in this innovative field. This book will be of interest to researchers and advanced students across nanotechnology, materials science, electrical engineering, mechanical engineering, chemistry, and biomedicine, as well as scientists, engineers, R&D professionals, and more.

Cellular Agriculture: Technology, Society, Sustainability and Science provides a state-of-the-art review of cellular agriculture technologies. From cell selection to scaffolding and everything in-between, this book contains chapters authored by leading cellular agriculture researchers and product developers across the world. Driven by consumer desire for sustainable food production, animal welfare improvements, and better human health, companies around the world are racing to engineer alternative protein products with the best flavour, appearance, and texture. A major challenge many of these early-stage companies struggle with is having the foundational science and technical knowledge to start their journey in this emerging industry. This text provides detailed information on the current state of the science and technology of cellular agriculture. It combines the social aspects that need to be considered to create a level playing field to give each emerging idea the best chance at realizing the ultimate vision of cellular agriculture: satisfying the demand for protein around the world in a way that is better for humans, animals, and the planet. This is the first resource of its kind to take a practical approach to review the design, feasibility, and implementation of cellular agriculture techniques. With additional chapters on life cycle analyses and ideal transition scenarios, this book provides a resource for aspiring technology developers and academics alike, seeking evidence-based assessments of the industry and its disruptive potential.

New Horizons in Modern Catalysis: Six Different Perspectives, Volume 72 in the Advances in Catalysis series, highlights new advances in the field, with this new volume presenting interesting chapters on Carbanion-functionalized phosphines: New design elements for catalyst development, Molecular Electrocatalysts for Organic Electrosynthesis, Mechanistic aspects of secondary sphere modification in organocatalysis, Earth-Abundant Transition Metal-Catalyzed reactions with Iodine(III) reagents: from catalysis to mechanistic studies, Design of metal nanoparticles for better performance in catalysis, and Computational design of industrially relevant enzymes.