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Computer-Aided Applications in Pharmaceutical Technology: Delivery Systems, Dosage Forms, and Pharmaceutical Unit Operations, Second Edition covers the fundamentals of experimental design application and interpretation in pharmaceutical technology, chemometric methods with an emphasis on their applications in process control, neural computing, data science, computer-aided biopharmaceutical characterization, as well as the application of computational fluid dynamics in pharmaceutical technology. Completely updated, the book introduces the theory and practice of computational tools through new case studies. Chapters cover Quality by Design in pharmaceutical development, overview data mining methodologies, present computer-aided formulation development, cover experimental design applications, and much more.
Connectomic Medicine: A Guide to Brain AI in Treatment Decision Planning examines how to apply connectomics to clinical medicine, including discussions on techniques, applications, novel ideas, and in case examples that highlight the state-of-the-art. Written by pioneers, this volume serves as the foundation for all neuroscience clinicians/researchers venturing into the field of AI medicine, its realistic applications, and how to integrate AI connectomics into clinical practice. With widespread applications in neurology, neurosurgery and psychiatry, this book is appropriate for anyone interested in cerebral network anatomy, imaging techniques, and insights into this emerging field.
Peptide and Protein Drug Delivery Using Polysaccharides offers an interdisciplinary discussion of polysaccharides applied in peptide and protein drug delivery. Chapters consider basic biology of different polysaccharides of current interest and their production at pilot and large-scale stages by various techniques including, but not limited to, cell and hairy root cultures. Other sections examine factors affecting polysaccharide absorption, metabolism, and excretion in nascent, encapsulated, or conjugated forms, with unique coverage of vaccine absorption, metabolism, and drug delivery. A final section considers analytical methods for detection in tissue fluids and homogenates. Accessible figures, tables, and graphical abstracts are included throughout to support understanding. Specific polysaccharides discussed for therapeutic purposes include cellulose, hyaluronic acid, heparin, carageenan, alginic acid, agar and myrrh, acacia, tragacanth, ghatti gum, chitin, chitosan, starch, glycogen and dextran.
Machine Learning Aided Analysis, Design, and Additive Manufacturing of Functionally Graded Porous Composite Structures presents a state-of-the-art review of the latest advances and cutting-edge technologies in this important research field. Sections provide an introduction to functionally graded porous structures and detail the effects of graded porosities on bending, buckling, and vibration behaviors within the framework of Timoshenko beam theory and first-order shear deformable plate theory. Other sections cover the usage of machine learning techniques for smart structural analysis of porous components as an evolution from traditional engineering and methods and focus on additive manufacturing of structures with graded porosities for end-user applications. The book follows a clear path from design and analysis to fabrication and applications. Readers will find extensive knowledge and examples of functionally graded porous structures that are suitable for innovative research and market needs, with applications relevant to a diverse range of industrial fields, including mechanical, structural, aerospace, energy, and biomedical engineering.
Earth Observation for Monitoring and Modeling Land Use presents a practical guide and theoretical overview of the latest techniques and Earth observation technologies applied to land use and land cover change through qualitative assessment of Earth observation technologies. The book's chapters include detailed case studies, Earth observation datasets, and detailed applications of the technologies covered that are presented in a way that each chapter is a self-contained guide on a specific application of Earth observation technologies to land use problems, ensuring all technical and background information is provided on each subject without the need for cross-referencing or searching for other sources.The book spatializes the understanding of monitoring land cover and use, and quantifies the challenges faced, allowing analysis of the dynamics of the territory in terms of occupation processes, land use, and its transformations. It focuses on practical applications of using remote sensing and modeling that support new research in relation to monitoring of land use and spectral modelling, elucidating the importance of advanced methodologies in the coverage and use mappings of the Earth.
The hydrostatic approach to ship stability aims to balance idealized ship weight against buoyancy forces. This textbook is a complete guide to understanding ship hydrostatics in ship design and ship performance. Adrian Biran guides readers from first principles through basic and applied hydrostatic and ship stability theory, and introduces contemporary mathematical techniques for hydrostatic modelling and analysis. Real life examples of the practical application of hydrostatics are used to explain the theory and calculations; and to illustrate the effect shifting weights and central gravity displacements have on overall ship stability. Ship Hydrostatics and Stability covers recent developments in the field of naval architecture such as parametric resonance (also known as the Mathieu effect), the effects of non-linear motions on stability, the influence of ship lines, and new international stability regulations for small vessels. Extensive use of computer techniques is made throughout.Adheres to international standards and terminologyIncludes real life practical examples and calculations to illustrate the hydrostatic approach to ship stability
Sustainable Process Intensification for Biocatalysis: Applications in Enzymology and Biotechnology, a new volume in the Foundations and Frontiers of Enzymology series, offers applied instruction in process intensification principles for applications in enzymology and biotechnology, helping researchers and practitioners implement these techniques across various uses and industries, from healthcare to food and biofuel. Leaders in the field discuss a full range of approaches and enabling technologies, from microwave to ultrasound, hydrodynamic cavitation, and combination chemical and biological catalysis techniques, such as multiphase reactors, microreactors, scale-bioprocesses, and enzyme cascades.Later chapters examine ongoing advances and their implementation across different industries, including pharmaceuticals, perfumes, polymers, and agrochemicals, with a final chapter discussing next steps in research and future directions. Throughout the book, and across applied examples, emphasis is placed on driving sustainable research approaches and manufacturing.
Advancement of Phenolic Acids in Drug Discovery: Fundamental and Applications offers comprehensive coverage of the ADMET profiles of phenolic acids, their extraction method and prospects for drug design and development. Chapters overview phenolic acids and their characterization, discuss the role of phenolic acids in plant systems, present sources and detailed extraction methods of phenolic acids, and cover phenolic acid mechanisms of action as it relates to several key diseases and health conditions, including their role as antioxidant agents, anti-inflammatory and analgesic drugs, anti-microbial drugs, anti-viral drugs, anti-cancer drugs, diabetes and metabolic dysfunctions, neurological disorders, cardiovascular diseases. The book's final chapters cover nanoscience aspects of phenolic acids, biomedical applications, and concludes with challenges and opportunities presented by phenolic acids. This is the ideal reference for researchers in the fields of drug development, both in academia and corporate settings. Researchers of related areas like food science and medicinal chemistry will also benefit from this in-depth profiling of therapeutical properties of phenolic acids.
Earthworm Technology in Organic Waste Management: Recent Trends and Advances is a suitable contribution to the Waste and The Environment: Underlying Burdens And Management Strategies series that will be helpful in classifying and broadly addressing assessments, mitigation strategies, and the management of organic wastes using earthworms. In addition, the book provides a summary of the latest findings on emerging pollution-related issues, their sustainable management, and future perspectives. The book covers recent trends and developments in organic waste management, including the use of earthworms in municipal and industrial waste management, the role of earthworms in vermifiltration/vermiwash, and of vermicompost in crops. Finally, the book covers the potential of earthworms in the remediation of emerging contaminants. This includes antibiotic resistance genes, heavy metals, pesticides, microplastics, and other emerging pollutants that are not covered in-depth in previously published titles.
Machine Learning Applications in Civil Engineering discusses machine learning and deep learning models for different civil engineering applications. These models work for stochastic methods wherein internal processing is done using randomized prototypes. The book explains various machine learning model designs that will assist researchers to design multi domain systems with maximum efficiency. It introduces Machine Learning and its applications to different Civil Engineering tasks, including Basic Machine Learning Models for data pre-processing, models for data representation, classification models for Civil Engineering Applications, Bioinspired Computing models for Civil Engineering, and their case studies. Using this book, civil engineering students and researchers can deep dive into Machine Learning, and identify various solutions to practical Civil Engineering tasks.
Ion-Exchange Chromatography and Related Techniques defines the current state-of-the-art in ion-exchange chromatography and related techniques and their implementation in laboratory and industrial practice. This book provides a compact source of information to facilitate the transfer of knowledge and experience acquired by separation science specialists to colleagues from diverse backgrounds who need to acquire fundamental and practical information to facilitate progress in research and management functions reliant on information acquired by separation. Individual chapters written by recognized experts lending credibility to the work will allow this book to serve as a high value reference source of current information for analytical and biopharmaceutical chemists.
Air Pollution Calculations: Quantifying Pollutant Formation, Transport, Transformation, Fate and Risks, Second Edition enhances the systems science aspects of air pollution, including transformation reactions in soil, water, sediment and biota that contribute to air pollution. This second edition will be an update based on research and actions taken since 2019 that affect air pollution calculations, including new control technologies, emissions measurement, and air quality modeling. Recent court cases, regulatory decisions, and advances in technology are discussed and, where necessary, calculations have been revised to reflect these updates. Sections discuss pollutant characterization, pollutant transformation, and environmental partitioning. Air partitioning, physical transport of air pollutants, air pollution biogeochemistry, and thermal reactions are also thoroughly explored. The author then carefully examines air pollution risk calculations, control technologies and dispersion models. The text wraps with discussions of economics and project management, reliability and failure, and air pollution decision-making.
Microalgal Biomass for Bioenergy Applications presents current methods, practical applications, and research trends on diverse biofuel products from microalgae. This comprehensive book provides analyses of microalgal biology, chemical and molecular engineering techniques to scale-up algal biomass processes and biofuels conversion, and economic feasibility of value-added bioenergy co-products from a variety of microalgal strains. Sections cover microalgal biomass availability, suitability, potential for biofuel applications, scientific and methodical aspects of biomass harvesting, sustainable and commercial applications of microalgal biofuels, including LCA, and the technological limitations and future perspectives on microalgal biofuels. Each section offers in-depth knowledge on the fundamental and practical aspects with reference to biofuels and bioenergy production from microalgae. This book will be a valuable update for students, researchers and industry professionals working in bioenergy, and will be of interest to microbial and environmental scientists and phycologists interested in practical applications for microalgae.
Planning and Operation of Container Terminals provides methodologies to optimize the design of container handling systems. The book offers various optimization models and details how to apply the models. In addition, it captures key points of academic research to provide a thorough and up-to-date guide on this rapidly changing field. Sections cover various aspects of terminal operation and propose key issues for their optimization. In addition, the relationships among various operational problems are described, along with tactics for the efficient utilization of resources. Students and professionals alike will find this a useful resource for getting up-to-speed in this dynamic field. The efficiency of a container terminal highly depends on the design of handling systems and operation methods of the terminal. In recent decades, the development of ports has become large-scale, modern and automatic, so it is necessary to learn about the design and operation of modern ports quickly and to understand the research hotspots, research frontiers and research status in the current field, as well as the use and innovation of research methods.
Cancer Stem Cells and Signaling Pathways explores the mechanism of cancer stem cell signaling pathways in cancer advancement, serving as an ideal reference guide for investigators with valuable answers to problems associated with anti-cancer treatments and an understanding of the crosstalk among the signaling pathways in CSC regulation. Despite recent advances in tumor therapy and a greater understanding of their biology, tumors continue to be a prevalent and fatal worldwide. According to a novel paradigm in tumor biology, a small percentage of the cells within a tumor known as cancer stem cells (CSCs) are predicted as a crucial population for tumor progression.
Zero-Dimensional Carbon Nanomaterials: Material Design Methods, Properties and Applications covers advances in carbon dots, graphene quantum dots, carbon quantum dots, fullerenes and their applications. This book explores important aspects of preparing these materials for specific applications and includes an overview of the most relevant synthesis methods, with special emphasis on newer green methods and material synthesis from biomass sources. Thorough discussion of the materials key properties, including unique optical and electronic properties to enable them for a wide range of applications is included, along with applications in the fields of photovoltaic cells, catalysis, sensors, biomedical, nano devices and energy storage. This book is suitable for researchers and practitioners in materials science and engineering and may also be helpful for chemists and chemical engineers.
Banana Peels Valorization: Sustainable and Eco-friendly Applications provides a global overview of world production, physicochemical and microbiological characteristics of Banana Peels and the various pathways for their valorization, considering the advantages, disadvantages and factors impacting on each way of valorization. Each chapter deals with sustainable applications based on the sector category. Such structure helps the audience from a specific field to easily identify the specific application. Successful case study of a banana processing by-products valorization is also presented. Written by a team of interdisciplinary experts, this is the ultimate valuable resource for agricultural or food engineers who work in the banana groves and in the banana processing industry, and also for Researchers working in correlated areas of food, environmental and energy fields.
Is Justice Real When "Reality? is Not?: Constructing Ethical Digital Environments examines how frameworks and concepts of justice should evolve in virtual worlds. Directed at researchers working in, or with an interest in virtual reality, as well as those interested in the fields of artificial intelligence and justice, this book covers research regarding impacts on human psychological states existing within alternative ethical frameworks. With chapters dedicated to behavioral impacts of virtual events, robotics and "unconscious", and human psychological states of role playing and existing, readers will be well-equipped to navigate the virtual worlds in which millions of people currently spend time.
Medical Additive Manufacturing: Concepts and Fundamentals provides an overview of the latest research in the field of additively manufactured medical materials. It starts with a broad overview of the current state of medical additive manufacturing and then dives into cutting-edge topics such as medical imaging technologies for additive manufacturing and computer-aided design principles for anatomic modeling. The chapters discuss the state of additive manufacturing in an array of medical fields such as radiology, tissue engineering, nuclear medicine, orthopedics, surgery, cardiology, neurology, optometry, obstetrics, and veterinary medicine. This book concludes with chapters discussing regulatory considerations for additive manufacturing in hospitals and what the future holds for the field.
Inorganic Biomaterials for Drug Delivery covers a wide range of inorganic biomaterial types and their properties, from traditional materials like ceramics, metallics, and bioglasses to novel composites and nano-engineered inorganic biomaterials. Biocompatibility, toxicity, and regulatory considerations are also thoroughly discussed, ensuring the reader is fully equipped for efficient biomaterials selection and utilization in drug delivery applications. This is a must-have reference for those working in the fields of materials science, biomedical engineering, pharmaceutical science, pharmacology, chemical engineering, and clinical science.
The Climate Energy Nexus: Understanding the Relationship between Energy Production Systems and Climate Trends offers fundamental material on energy and climate systems, progressing to establishing advanced and integrated energy-climate models. Describing the motivation and key challenges in the climate-energy modeling community, this reference looks at the fundamentals of climate and energy systems before integrating them into a cohesive analysis framework. The book presents various energy production optimization case studies spanning urban and national scales, annual to multi-decade long timescales, and various economic and environmental considerationsPractitioners and students interested in climate and energy systems will gain a foundational platform from which to develop informed assessments of future energy use. As making informed energy planning decisions requires a better understanding of how climate trends, extreme events, and public policy could impact energy production performance, cost, and emissions, this book is an ideal resource for readers.
All-Dielectric Nanophotonics aims to review the underlying principles, advances and future directions of research in the field. The book reviews progress in all-dielectric metasurfaces and nanoantennas, new types of excitations, such as magnetic and toroidal modes and associated anapole states. Ultrahigh-Q resonant modes such as bound states in the continuum are covered and the promise of replacing conventional bulky optical elements with nanometer-scale structures with enhanced functionality is discussed. This book is suitable for new entrants to the field as an overview of this research area. Experienced researchers and professionals in the field may also find this book suitable as a reference.
Nanostructured Carbon Materials from Plant Extracts: Synthesis, Characterization, and Applications guides the reader through the preparation and utilization of carbon nanomaterials based on various biomass sources, including fruits, vegetables, leaves, pulp and other plant extracts. The book covers the fundamentals of nanostructured carbon materials and synthesis methods from a range of plant sources. Other chapters focus on characterization, analysis, simulation and modeling in order to prepare plant extract based carbon nanomaterials with the required properties. Final sections highlight key application areas, presenting methods and approaches to prepare these materials for specific uses. This book will be of interest to researchers and advanced students across nanomaterials, polymer science, composite science, sustainable materials, chemistry, chemical engineering, and materials science, as well as industrial scientists, engineers, and R&D professionals with an interest in sustainable carbon nanomaterials.
Bacterial Laccases: Engineering, Immobilization, Heterologous Production, and Industrial Applications provides a list of approaches that upgrades bacterial laccases to industrially relevant enzymes. Providing protocols for enzyme production and downstream processing, and including up-to-date information on bacterial laccases, as well as techniques that can be explored to enhance properties and production levels, this book clarifies research gaps and explains how they can be dealt with. Written for research scholars working on enzymes, this is a valuable tool for industries and policymakers.
A Natural History of Bat Foraging: Evolution, Physiology, Ecology, Behavior, and Conservation offers an all-inclusive resource on all aspects encompassing the vital process of foraging for bats. The book explores knowledge in the field, including sensory ecology, the development of cognitive maps, bat microbiomes, and molecular approaches to studying a bat's diet. It covers the importance of foraging in biology, from evolution and natural selection, to physiology, behavior, ecology, and natural history. In addition, it provides a unique focus on the implications of bat foraging for conservation purposes, including the role that molecular biology can play in preventing species depletion or extinction. With over 1,400 species, bats are among the most diverse vertebrate groups, having evolved an astonishingly broad range of foraging strategies to adapt to nearly all global regions and environments. The book assesses manmade and environmental issues that bats must overcome to ensure survival and prevent extinction. Written by international leaders in bat research, this is the ideal resource for bat specialists and conservationists, as well as zoologists, animal behaviorists, and academics associated with such disciplines.
Additive Manufacturing of Glass: From Science to Applications is a joint effort by the global glass 3D printing community, highlighting the current state of the art, its various applications, as well as its game-changing potential for a wide array of industries in the coming decades. The book starts with separate overviews of glass and additive manufacturing, gradually tying the two together to discuss topics such as melt-derived additive manufacturing of glass, sol-gel chemistry, direct ink deposition techniques, etching-based glass structuring, and slurry-based glass 3D printing. The book then concludes with various case studies and applications for 3D-printed glass, highlighting individual companies producing it and product applications such as bioactive glasses and micro-optics.
This book is a guide to the application of ionic liquids (ILs) in the oil industry. It includes ten chapters that review basic and advanced topics. Starting with a general introduction to IL structure and properties, the book comprehensively explains the use of ILs in key petroleum extraction processes such as pollutant removal, demulsification, crude oil transport and oil recovery. Additional applications that are important for the sustainability management of petrochemical operations such as deepwell hydrate inhibition, CO2 capture, corrosion engineering, catalysis, hydrocarbon separation, bitumen extraction and stabilization are also included. Each chapter also provides bibliographic references for further reading. The wide range of topics makes this an informative reference to students and professionals in petroleum engineering, chemical engineering programs and any other training course that requires reading material for an understanding of the oil industry. General readers and researchers interested in the fascinating chemistry of ionic liquids will also enjoy this book.
Handbook of Thermal Management Systems: e-Mobility and Other Energy Applications is a comprehensive reference on the thermal management of key renewable energy sources and other electronic components. With an emphasis on practical applications, the book addresses thermal management systems of batteries, fuel cells, solar panels, electric motors, as well as a range of other electronic devices that are crucial for the development of sustainable transport systems. Chapters provide a basic understanding of the thermodynamics behind the development of a thermal management system, update on Batteries, Fuel Cells, Solar Panels, and Other Electronics, provide a detailed description of components, and discuss fundamentals. Dedicated chapters then systematically examine the heating, cooling, and phase changes of each system, supported by numerical analyses, simulations and experimental data. These chapters include discussion of the latest technologies and methods and practical guidance on their application in real-world system-level projects, as well as case studies from engineering systems that are currently in operation. Finally, next-generation technologies and methods are discussed and considered.
Novel Nanostructured Materials for Electrochemical Bio-sensing Applications presents a detailed overview into the fabrication of electrochemical bio-sensing devices. The book addresses the challenges and opportunities relating to sustainable and biocompatible sensors from food, water and wearable applications to the various nanostructured biocompatible materials required for sensor fabrication. In addition, it explores the connection between nanomaterials and sensors and takes into consideration different and novel approaches such as toxic materials monitoring and health issues correlated with the use of nanomaterials. Users will find exciting insight into innovations in nanostructured electrochemical biosensing. By providing its audience with fundamentals, limitations, challenges, future perspectives and practical sustainability, this book will serve as a reference source researchers and engineers within analytical chemistry and electrochemistry.
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