Bøker utgitt av Elsevier Science

Proteolytic enzymes are found in all life forms, where they catalyze peptide bond hydrolysis during essential biological processes. Proteases of various pathogens have also been shown to use endogenous protease inhibitors to regulate the activity of host proteolytic enzymes encountered during infection.Proteolytic Enzymes and their Inhibitors in Infectious Pathogens brings together key experts to provide a thorough discussion of proteolytic enzymes and their endogenous inhibitors found in parasites, bacteria, and viruses. The book focuses on the respective roles of the different catalytic classes of proteolytic enzymes and their protein-protease inhibitors at the host-infectious organism interface, and how this knowledge may inform drug and vaccine design. Following a foundational overview of proteases and macromolecular inhibitors of pathogenic organisms, authors discuss recent research on distinct classes of proteolytic enzymes in pathogens. Classes include aspartic proteases, cysteine proteases, metalloproteases, serine proteases, and threonine proteases with experts contributing chapters on distinct enzymes and inhibitors. New methods to identify protease substrates and inhibitors are also provided, with step-by-step protocols to advance new research and drive drug discovery.

Application of Gellan Gum as a Biomedical Polymer details key topics and fundamental aspects of gellan gum and its biomedical applications in drug delivery, proteins and peptides delivery, cell delivery, tissue engineering, wound dressings and enzyme immobilizations in developing high quality products. Sections introduce gellan gum, its source, production and gelation mechanism, discuss biomedical materials, and provides ways it can be used for biomedical applications. The book also examines the used of gellan gum as pharmaceutical excipients for drug delivery. Future developments and challenges round out the book's coverage.With contributions for an international group of experts, this book is a useful reference for scientists, researchers and those in industry engaged in biomedical product development using natural polysaccharides.

Progress and Prospect of Nanocarriers: Design, Concept, and Recent Advances examines the different nanocarriers that are currently being developed for specific applications in biomedical drug delivery, disease management, diagnosis and therapy. Nanosized drug delivery systems have gained tremendous amounts of clinical interest due to their effective bio-distribution and enhanced pharmacokinetic and selective targeting capability which results in high therapeutic potential, low side effects, and the generation of cost-effective drug delivery systems. Numerous effective nanocarriers have been evolving, including polymeric nanoparticles, liposomes, microspheres, dendrimers, and carbon nanotubes.This book is a helpful reference for scientists and students in the fields of drug delivery, biomaterials and nanomedicine, as well as scientists and engineers in industrial disciplines of drug delivery and drug formulation.

Heat Pipes: Theory, Design and Applications, Seventh Edition, takes a highly practical approach to the design and selection of heat pipes, making it an essential guide for practicing engineers and an ideal text for postgraduate students. The expanded author team consolidate and update the theoretical background included in previous editions, and include new sections on recent developments in manufacturing methods, wick design and additional applications. The book serves as an introduction to the theory, design and application of the range of passive, two-phase, heat-transfer devices known as heat pipes, serving as an essential reference for those seeking a sound understanding of the principles of heat pipe technology. It provides an introduction to the basic principles of operation and design data which would permit the reader to design and fabricate a basic heat pipe. It also provides details of the various more complex configurations and designs currently available to assist in selecting such devices.This new edition has been fully updated to reflect the latest research and technologies and includes four brand new chapters on various types of heat pipe, theoretical principles of heat transfer and fluid mechanics, additive manufacturing and heat pipe heat exchangers.

Artificial Intelligence and Machine Learning in Healthcare discusses the potential of groundbreaking technologies on the delivery of care. A lot have been said about how artificial intelligence and machine learning can improve healthcare, however there are still many doubts and concerns among health professionals, all of which are addressed in this book. Sections cover History and Basic Overview of AI and ML, with differentiation of supervised, unsupervised and deep learning, Applications of AI and ML in Healthcare, The Future of Healthcare with AI, Challenges to Adopting AI in Healthcare, and ethics and legal processes for implementation.This book is a valuable resource for bioinformaticians, clinicians, graduate students and several members of biomedical field who needs to get up to speed on the revolutionary role of AI and Machine Learning in healthcare.

3D Printing in Biotechnology: Current Technologies and Applications explains the basic designs and recent progress in the application of 3D printing within various biotechnology fields. The book is a compilation of the basic fundamentals, designs, current applications, and future considerations related to this emerging technology, and summarizes the promising application of 3D bioprinting. Chapters contain detailed state-of-the-art knowledge to assist in the development and design of 3D printers, with applications in the medical, food, and environmental fields. This book will appeal to researchers and students from different disciplines, including materials science and technology, food, agriculture, and various biomedical fields.The content includes industrial applications and fills the gap between the research conducted in the laboratory and practical applications in related industries.

Methodological and Technological Advances in Death Investigations: Application and Case Studies focuses on advancements in both methods and technology in death investigations. Specifically, in the areas of latent fingerprints, facial recognition, wildlife forensics, using aerial vehicles and 3D-ID. The combination of national and international authors and a discussion of the state of forensic science over a decade after the National Academies 2009 Report, Strengthening Forensic Science in the United States: A Path Forward, further highlights the boundaries, limitations and context in which these newer technologies and applications act synergistically to enhance forensic science.

Climate Crisis, Energy Violence: Mapping Fossil Energy’s Enduring Grasp on Our Precarious Future communicates the breadth and scope of fossil fuel infrastructure and its global impact. Comparative research coupled with data and maps accentuates the spatial, temporal, and physical forms of energy violence. Over 25 international case studies track the world’s three primary fossil fuels-first coal, followed by oil, then gas-revealing patterns of loss and damage, as well as industrial tactics of climate delay and deception used to prolong fossil fuel harms. Through analyses of hotspots, sacrifice zones, fast vs slow violence, death prints and fuel life cycles, immediate ecological damage as well as long-term climate impacts are revealed, tied directly to fossil fuel interests. In detailing the broad scope of damage from energy extraction systems, this book provides a compelling argument to move past fossil fuels, directly confronting the climate crisis through energy justice alliances.

Extraction Processes in the Food Industry, a volume in the Unit Operations and Processing Equipment in the Food Industry series, explains the processing operations and equipment necessary for extraction of different food ingredients and nutraceuticals, including conventional and modern extraction techniques. These processes and unit operations are very important in the manufacture of products such as edible oils, sugars, coffee, tea, essential oils, and other products.Divided in three sections, "Different extraction equipment and technologies," "Application of extraction in the food industry," and "Design, control and efficiency of extraction systems," all chapters emphasize basic texts relating to experimental, theoretical, computational, and/or applications of food engineering principles and the relevant processing equipment for extraction unit operations.Written by food engineering experts, Extraction Processes in the Food Industry is a useful resource for industrial engineers working in the field of food processing and within food factories, providing information on particular food processing operations and equipment.

Food Packaging and Preservation: Antimicrobial Materials and Technologies provides a scaffolded introduction to principles of biological science (food contamination and their effect on human health) as well as nanomaterials, natural antimicrobials and emerging non-thermal processing methods. The book's goal is to help users develop sustainable usage of these materials and technologies. It is designed to help researchers in food technology, materials science, nanoscience, and polymer science, but it will also be ideal for researchers and developers who develop antimicrobial technologies for food industry applications, in particular food packaging and the preservation of food products.

Digital Health Maturity, Innovation, and Quality Improvement provides a roadmap to move from endless pilots and ad hoc system purchases to a systematic, stepwise and integrated approach to increasing digital health capacity. Specific guidelines, tools and use cases are discussed to show how the digital health maturity model (DHMM) can be put into actual practice. Topics cover foundations of DHMM and how to put them into practice, organizational considerations for implementation, and best practices, tools and pitfalls to avoid. In addition, the book discusses the future of DHMM and the impact of a global adherence to digital health.This is a valuable resource for researchers, students, policymakers, governments and anyone who is interested in learning more about digital health and its worldwide benefits.

The Science and Technology of Cement and other Hydraulic Binders covers the design of Portland Cement composition using the ideas and formulae of earlier scientists, including the calculation of proportions of different cement phases formed during processing. Other chapters cover cement manufacture by dry, semi-dry or wet processes using rotary and shaft kilns. Particular attention is given to the physical changes that occur in the raw mix when affected by chemical processes. The chemistry of clinker formation which is concerned chiefly with high temperature reactions in the solid-state phase or reactions in the presence of the liquid phase is also discussed. Users will find the latest information on the storage of cement, its packing and handling, hydration and setting, Gypsum, different mineral additions, and advances in special and newer cements, including blended cements, Portland slag cement, Pozzolanic cements, high alumina cements, high-strength cement-based materials, fiber-reinforced cement, non-Portland cements and lime.

Sustainable Biorefining of Woody Biomass to Biofuels and Biochemicals explores various technologies and pathways for the valorization of woody biomass to produce sustainable biofuels and bioproducts. Focusing on commercialization, the book discusses woody biomass availability, including harvesting, transportation and storage, biomass structure, advanced biorefinery technologies, and the economic and environmental sustainability of woody biomass-based biorefineries. Various technologies are described and assessed from a commercial perspective and practical solutions to the latest challenges are provided. The last section of the book is dedicated to the commercialization aspects of biorefineries, providing details about the techno-economic viability and environmental impact of various biorefinery approaches.This book provides readers with a unique and comprehensive reference that will help students and researchers alike identify and overcome the challenges involved in woody-biomass biorefining for biofuels and biochemicals. It will also be of interest to researchers and professionals involved more broadly in bioenergy and renewable energy, and interdisciplinary teams working across biotechnology, chemistry and chemical engineering, environmental science, and plant sciences.

Red Panda: Biology and Conservation of the First Panda, Second Edition, provides the most up-to-date research, data, and conservation solutions for the red pandas, Ailurus species. Since the publication of the previous edition in 2010, the International Union for Conservation of Nature (IUCN) updated the threat level of red pandas, and they are now considered to be endangered. This latest edition is updated to provide an in-depth look at the scientific and conservation-based issues urgently facing the red panda today. Led by one of the world's leading authorities and advocates for red panda conservation, this new edition includes data from the Population and Habitat Viability (PHVA) workshops conducted in three of the species' range states, Nepal, China, and India; these workshops utilized firsthand information on the decrease of red panda populations due to factors including deforestation, illegal pet trade, human population growth, and climate change. This book also includes updated information from the first edition on reproduction, anatomy, veterinary care, zoo management, and fossil history.

Covers characterisation of performance, durability, and colour fastness of apparels along with mandatory regulations on flammability, fibre composition and care labels. The unique feature of the book is that the topics are oriented on the practical way in which manufacturing units, buying agents and retailers are dealing with day to day challenges.

Food engineering is a required class in food science programs, as outlined by the Institute for Food Technologists (IFT). The concepts and applications are also required for professionals in food processing and manufacturing to attain the highest standards of food safety and quality.The third edition of this successful textbook succinctly presents the engineering concepts and unit operations used in food processing, in a unique blend of principles with applications. The authors use their many years of teaching to present food engineering concepts in a logical progression that covers the standard course curriculum. Each chapter describes the application of a particular principle followed by the quantitative relationships that define the related processes, solved examples, and problems to test understanding.The subjects the authors have selected to illustrate engineering principles demonstrate the relationship of engineering to the chemistry, microbiology, nutrition and processing of foods. Topics incorporate both traditional and contemporary food processing operations.

The petroleum geologist and engineer must have a working knowledge of petrophysics in order to find oil reservoirs, devise the best plan for getting it out of the ground, then start drilling. This book offers the engineer and geologist a manual to accomplish these goals, providing much-needed calculations and formulas on fluid flow, rock properties, and many other topics that are encountered every day. New updated material covers topics that have emerged in the petrochemical industry since 1997.Contains information and calculations that the engineer or geologist must use in daily activities to find oil and devise a plan to get it out of the groundFilled with problems and solutions, perfect for use in undergraduate, graduate, or professional coursesCovers real-life problems and cases for the practicing engineer