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The inside story of an unprecedented feat of science and business.At the start of 2020, Moderna was a biotech unicorn with dim prospects. Yes, there was the promise of its disruptive innovation that could transform medicine by using something called messenger RNA, one of the body's building blocks of life, to combat disease. But its stock was under water. There were reports of a toxic work culture. And despite ten years of work, the company was still years away from delivering its first product. Investors were getting antsy, or worse, skeptical.Then the pandemic hit, and Moderna, at first reluctantly, became a central player in a global drama?a David to Big Pharma's Goliaths?turning its technology toward breaking the global grip of the terrible disease. By year's end, with the virus raging, Moderna delivered one of the world's first Covid-19 vaccines, with a stunningly high rate of protection. The achievement gave the world a way out of a crippling pandemic while validating Moderna's technology, transforming the company into a global industry power. Biotech, and the venture capital community that fuels it, will never be the same.Wall Street Journal reporter Peter Loftus, veteran reporter covering the pharmaceutical and biotech industries and part of a Pulitzer Prize?finalist team, brings the inside story of Moderna, from its humble start at a casual lunch through its heady startup days, into the heart of the pandemic and beyond. With deep access to all of the major players, Loftus weaves a tale of science and business that brings to life Moderna's monumental feat of creating a vaccine that beat back a deadly virus and changed the business of medicine forever.The Messenger spans a decade and is full of heroic efforts by ordinary people, lucky breaks, and life-and-death decisions. It's the story of a revolutionary idea, the evolution of a cutting-edge American industry, and one of the great achievements of this century.

What will you do when your AI misbehaves?The promise of artificial intelligence is automated decision-making at scale, but that means AI also automates risk at scale. Are you prepared for that risk?Already, many companies have suffered real damage when their algorithms led to discriminatory, privacy-invading, and even deadly outcomes. Self-driving cars have hit pedestrians; HR algorithms have precluded women from job searches; mortgage systems have denied loans to qualified minorities. And often the companies who deployed the AI couldn't explain why the black box made the decision it did.In this environment, AI ethics isn't merely an academic curiosity, it's a business necessity. In Ethical Machines, Reid Blackman gives you all you need to understand AI ethics as a risk management challenge. He'll help you build, procure, and deploy AI in a way that's not only ethical but also safe in terms of your organization's reputation, regulatory compliance, and legal standingand do it at scale.And don't worrythe book's purpose is to get work done, not to ponder deep and existential questions about ethics and technology. Blackman's clear and accessible writing helps make a complex and often misunderstood concept like ethics easy to grasp. Most importantly, Blackman makes ethics actionable by tackling the big three ethical risks with AIbias, explainability, and privacyand tells you what to do (and what not to do) to mitigate them.With practical approaches to everything from writing a strong statement of AI ethics principles to creating teams that effectively evaluate ethical risks, Ethical Machines is the one guide you need to ensure your AI advances your company's objectives instead of undermining them.

""What does a workplace utopia look like to you?" This is the question Dr. Ella F. Washington asks companies, and often she hears about an ideal vision of an organization that values diversity and inclusion and wants employees to bring their whole selves to work. Many organizations desire this ideal vision and know that it's a journey to get there-but still don't know what's required to make the journey. Organizations have largely missed the mark when it comes to creating environments where all employees thrive in an equal and equitable way, because they treat diversity, equity, and inclusion (DEI) as a program that gets done rather than the necessary and difficult journey it is. A truly inclusive workplace requires invention and reinvention, mistakes and humility, adaptation to a changing world, constant self-reflection, and sometimes significant sacrifice. The road to an inclusive workplace is a difficult one, but you can traverse it, and there's help along the way. Start here with stories of companies making the necessary journey, including Slack, Kaiser Permanente, and PwC. Hear from their leaders about their successes and failures, times they were on the vanguard, and the moments they realized they had much more work to do. These are profiles in perseverance from people who are keen enough to recognize the need for inclusive workplaces and humble enough to know they're not there yet. Washington brings her years of experience as a DEI leader in multiple industries to give you a frame for thinking about where these companies are on their journey and where you may be, too. Progress is hard-won on the necessary journey to becoming an inclusive organization, but it must be won. John Lewis said it best: "You see something you want to get done, you cannot give up, and you cannot give in.""--

For fans of Yuval Harari's bestsellers Sapiens and Homo Deus, a psychology-technology-self-help book about the seismic impact that AI will have on the way we work and live, and what we as humans can do to adapt to our new reality and ensure that technology enhances, not alienates, us.Fascinating perspective on the seismic impact that AI will have on the way we work and live.Entertaining stories and conversational voice.Provides practical advice for how individuals can adapt and thrive as AI evolves.Audience:Smart business readers who are interested in technology and how it affects our lives.Readers of popular psychology books.Readers of bestsellers from the likes of Steven Pinker and Yuval Harari.

Lead your business through the crisis.As the pandemic is exacting its toll on our lives and wreaking havoc in the global economy, HBR is helping companies and managers make sense of this unprecedented situation and lead employees through it. What should you and your company be doing right now to counter these challenges?Coronavirus and Business: The Insights You Need from Harvard Business Review is a compilation of sixteen recent articles from HBR.org. It provides you with essential thinking about keeping your company running remotely, managing your business through disaster and recovery, and finding it within yourself to lead with resilience through the crisis.Business is changing. Will you adapt or be left behind? Get up to speed and deepen your understanding of the topics that are shaping your company's future with the Insights You Need from Harvard Business Review series. Featuring HBR's smartest thinking on fast-moving issues--blockchain, cybersecurity, AI, and more--each book provides the foundational introduction and practical case studies your organization needs to compete today and collects the best research, interviews, and analysis to get it ready for tomorrow.You can't afford to ignore how these issues will transform the landscape of business and society. The Insights You Need series will help you grasp these critical ideas--and prepare you and your company for the future.

In an ideal world, our work lives would be completely fulfilling, full of meaning, and intrinsically motivating. So what if you're stuck in a job and your heart isn't in it anymore? Or what if your team is feeling disconnected from your company's mission? This book shows how to use passion as a compass to find the job that's right for you--and to connect with the deeper purpose of your work

Did you know that job candidates who jokingly ask for high salaries receive better offers than those who don't? Or that retail salespeople who mimic the way their customers speak and behave end up selling more? Culled from Harvard Business Review's popular newsletter, The Daily Stat, this book offers a look at insights that both amuse and inform.

The best of Clayton Christensen's seminal work on disruptive innovation, all in one place.No business can afford to ignore the theory of disruptive innovation. But the nuances of Clayton Christensen's foundational thinking on the subject are often forgotten or misinterpreted. To achieve continuing growth in your business while defending against upstarts, you need to understand clearly what disruption is and how it works, and know how it applies to your industry and your company. In this collection of Christensen's most influential articles-carefully selected by Harvard Business Review's editors-his incisive arguments, clear theories, and readable stories give you the tools you need to understand disruption and what to do about it. The collection features Christensen's newest article looking back on 20 years of disruptive innovation: what it is, and what it isn't.Covering a broad spectrum of topics-business model innovation, mergers and acquisitions, value-chain shifts, financial incentives, product development-these articles illuminate the impact and implications of disruptive innovation as well as Christensen's broader thinking on management theory and its application in business and in life.This collection of best-selling articles includes: "e;Disruptive Technologies: Catching the Wave,"e; by Joseph L. Bower and Clayton M. Christensen, "e;Meeting the Challenge of Disruptive Change,"e; by Clayton M. Christensen and Michael Overdorf, "e;Marketing Malpractice: The Cause and the Cure,"e; by Clayton M. Christensen, Scott Cook, and Taddy Hall, "e;Innovation Killers: How Financial Tools Destroy Your Capacity to Do New Things,"e; by Clayton M. Christensen, Stephen P. Kaufman, and Willy C. Shih, "e;Reinventing Your Business Model,"e; by Mark W. Johnson, Clayton M. Christensen, and Henning Kagermann, "e;The New M&A Playbook,"e; by Clayton M. Christensen, Richard Alton, Curtis Rising, and Andrew Waldeck, "e;Skate to Where the Money Will Be,"e; by Clayton M. Christensen, Michael E. Raynor, and Matthew Verlinden, "e;Surviving Disruption,"e; by Maxwell Wessel and Clayton M. Christensen, "e;What Is Disruptive Innovation?"e; by Clayton M. Christensen, Michael E. Raynor, and Rory McDonald, "e;Why Hard-Nosed Executives Should Care About Management Theory,"e; by Clayton M. Christensen and Michael E. Raynor, and "e;How Will You Measure Your Life?"e; by Clayton M. Christensen.

Uses stories from a range of top companies to illustrate why building loyalty is more important than ever - and how to do it.

"The one book every innovator and every entrepreneur needs to make a difference in the world. Social innovation and social entrepreneurship are rising forces in the world. As stakeholder capitalism takes root, and as the extent of systemic challenges becomes clear-from climate change to income inequality to food security to healthcare and beyond-more and more of the best and brightest will feel a calling to become innovators and entrepreneurs who develop and deploy solutions to the world's thorniest problems. But it won't be easy: innovation is not the prerogative or privilege of any organizational form or legal structure. Solutions often require the active collaboration of constituents across government, business, and the nonprofit worlds. Social innovators and entrepreneurs need a handbook to guide them on the journey to changing the world. Frontiers in Social Innovation is an essential volume for becoming a difference maker. Filled with contributions from a who's who of the smartest thinkers and most experienced practitioners, Frontiers in Social Innovation provides the knowledge you need to succeed as a social innovator. Contributions cover the waterfront, including: high-performance leadership to drive social change, design for extreme affordability, scaling social innovation, corporate decarbonization, social innovation and healthcare in the postpandemic world, donor-advised funds and impact investing. Through the voices of those already doing it, including Paul Brest, Kim Starkey, Matthew Bannick, Gloria Lee, and many more, Frontiers in Social Innovation brings to life the challenges and opportunities of the field through case studies in healthcare, education, climate, and responding to a global pandemic. No stone is left unturned in this indispensable volume for anyone who wants to make a difference in the world through innovation and entrepreneurship"--

Your next act starts now.You're ready for something new, but it's hard to start over. Just the idea of trading the security you have now for the unknown or throwing away the education and time you've invested in your current career can plunge you into a swirl of indecision and anxiety. But mixing things up every few years is an increasingly normal and cyclical part of a healthy work life--a way to gain new skills and stretch your existing ones by applying them to different contexts.Whether you know what you want to do next or you're still evaluating options, the HBR Guide to Changing Your Career will help you:Imagine other professional selvesIdentify the skills you need--and those you already possess that will transfer to another industryAssess the financial implications of the change you're consideringTry out new roles without endangering your current jobExplain a seemingly winding career pathPitch yourself into a new role

Effective marketing can mean the difference between runaway successes and costly flops. Covering everything from customer programs to ad campaigns to sales promotions, this guide for marketers, aims to help them to turn opportunities into profits.

Is your company a storytelleror a storydoer?The old way to market a business was storytelling. But in todays world, simply communicating your brands story in the hope that customers will listen is no longer enough. Instead, your authentic brand must be evident in every action the organization undertakes. Todays most successful businesses are storydoers. These companies create products and services that, from the very beginning, are manifestations of an authentic and meaningful storyone told primarily through action, not advertising. In True Story, creative executive Ty Montague argues that any business, regardless of size or industry, can embrace the principles of storydoing. Indeed, our best-run companiesfrom small start-ups to global conglomeratesorganize around a coherent narrative that is then broadcast through every action they take (from product design to customer service to marketing). Montague shows why storydoing firms are nimble, more adaptive to change, and more efficiently run businesses.Montague is a founder of the growth consultancy co:collective and the former president and CCO of J. Walter Thompson, the largest advertising agency in North America. He brings his depth of creative business experience to the book and provides a clear framework and proven process for bringing you and your customers together in the creation of your brand story. Montague introduces five critical elementswhat he calls the the four truths and the action mapthat are the foundation of storydoing: the participants (your customers, partners, and employees) the protagonist (your company today) the stage (the world around your business) the quest (your driving ambition and contribution to the world) your action map (the actions that will make your story real for participants)The book is filled with examples of how forward-thinking organizationsincluding Red Bull, Shaklee, Grind, TOMS Shoes, and News Corporationare effectively using storydoing to transform their organizations and drive extraordinary results.

ARE YOUR WORKING RELATIONSHIPS WORKING AGAINST YOU?To achieve your goals and get ahead, you need to rally people behind you and your ideas. But how do you do that when you lack formal authority? Or when you have a boss who gets in your way? Or when you're juggling others' needs at the expense of your own?By managing up, down, and across the organization. Your success depends on it, whether you're a young professional or an experienced leader.The HBR Guide to Managing Up and Across will help you:Advance your agenda-and your career-with smarter networkingBuild relationships that bring targets and deadlines within reachPersuade decision makers to champion your initiativesCollaborate more effectively with colleaguesDeal with new, challenging, or incompetent bossesNavigate office politics

Whats your entrepreneurial profile?Do you have what it takes to build a great business?In this book, three prominent business leaders and entrepreneursnow venture capitalists and CEO advisersshare the qualities that surface again and again in those who successfully achieve their goals. The common traits? Heart, smarts, guts, and luck.After interviewing and researching hundreds of business-builders across the globe, the authors found that every one of themfrom young founder to seasoned CEOholds a combination of these four attributes. Indeed each of us tends to be biased toward one of these traits in our decision-making, and figuring out which trait drives you will lead to greater self-awareness and likelihood of success in starting and growing a business.So are you: Heart-dominant, like renowned chef Alice Waters or Starbuckss Howard Schultz? Smarts-dominant, like Jeff Bezos of Amazon or legendary investor Warren Buffett? Guts-dominant, like Nelson Mandela or Virgins Richard Branson? Or are you most defined by the luck trait, like Tony Hsieh of Zappos (and a surprisingly high proportion of other successful entrepreneurs)?Heart, Smarts, Guts, and Luck includes the first Entrepreneurial Aptitude Test (E.A.T), a simple tool to help determine your specific profile.Though no single archetype for entrepreneurial success exists, this book will help you understand which traits to dial up or dial down to realize your full potential, and when these traits are most and least helpful (or even detrimental) during critical points of a company lifecycle. Not only will you know how to build a better business faster, youll also take your natural leadership style to the next level.

What does it take to lead a global business?What makes being a global business leader today such a complex task? Its more than mastering your knowledge of various geographies and cultures, though that is essential. But to succeed, you must also master the complex mind-set and competencies needed to lead in todays fully globalized world. Not an easy assignment.Enter ngel Cabrera and Gregory Unruh. In Being Global, they pull from their extensive experience as well as research they conducted at the Thunderbird School of Global Management, which has been cited by the Financial Times, U.S. News and World Report, and The Economist for its authority on global business. In Being Global, Cabrera and Unruh define a new context for global leadership, vividly illustrating both the challenges and the opportunities facing todays executives. How can you be effective? What new skills must you learn in order to be successful? What do international teams do to stay connected while still producing results on a regional scale?Being Global is written for leaders at all levels of their careerswhether in big business or small, private sector or governmentwho aspire to think and act globally and who need some help getting there. Being a global citizen is just the starting point. Cabrera and Unruh provide the tools and guidance to help you develop even deeper leadership skills, to benefit both you and your organization.

The definitive work on business strategy for sustainability by the most authoritative voice in the conversation.More than ever before, consumers, employees, and investors share a common purpose and a passion for companies that do well by doing good. So any strategy without sustainability at its core is just plain irresponsible - bad for business, bad for shareholders, bad for the environment. These challenges represent unprecedented opportunities for big brands - such as Clorox, Dell, Toyota, Procter & Gamble, Nike, and Wal-Mart - that are implementing integral, rather than tangential, strategies for sustainability. What these companies are doing illuminates the book's practical framework for change, which involves engaging employees, using transparency as a business tool, and reaping the rewards of a networked organizational structure.Leave your quaint notions of corporate social responsibility and environmentalism behind. Werbach is starting a whole new dialogue around sustainability of enterprise and life as we know it in organizations and individuals. Sustainability is now a true competitive strategic advantage, and building it into the core of your business is the only means to ensure that your company - and your world - will survive.

Do you have an employee whose performance keeps deterioratingdespite your close monitoring? Brace yourself: You may be at faultby unknowingly triggering the set-up-to-fail syndrome. Perhaps things started off swimmingly. But then something--a missed deadline, a lost clientmade you question the person's performance. You began micromanaging him. Suspecting your reduced confidence, he started doubting himselfand stopped giving his best. You viewed his new behavior as additional proof of mediocrity, and tightened the screws further. In The Set-Up-to-Fail Syndrome, Jean-Francois Manzoni and Jean-Louis Barsoux show how this insidious cycle hurts everyone: employees stop volunteering ideas, preventing your organization from getting the most from them; you lose energy to attend to other activities; and your reputation suffers as other employees deem you unfair. Team spirit wilts as targeted performers are alienated. But the set-up-to-fail syndrome doesn't have to happen. The authors provide preventive measures, such as loosening the reins as new employees master their jobs. If the syndrome has already erupted, Manzoni and Barsoux explain how to discuss the dynamic with your employee and reverse the cycle.

When it comes to project management, success lies in the details. Part of the "The Harvard Business Essentials Series", this book walks managers through every step of project oversight from start to finish. It offers information on everything from planning and budgeting to team building and after-project reviews.

Every day, individuals take action based on how they believe innovation will change industries. Yet these beliefs are largely based on guesswork and incomplete data and lead to costly errors in judgment. Now, internationally renowned innovation expert Clayton M. Christensen and his research partners Scott D. Anthony and Erik A. Roth present a groundbreaking framework for predicting outcomes in the evolution of any industry. Based on proven theories outlined in Christensen's landmark books The Innovator's Dilemma and The Innovator's Solution, Seeing What's Next offers a practical, three-part model that helps decision-makers spot the signals of industry change, determine the outcome of competitive battles, and assess whether a firm's actions will ensure or threaten future success. Through in-depth case studies of industries from aviation to health care, the authors illustrate the predictive power of innovation theory in action.

Building anti-racist companies by design creates great places to work for all.Business leaders ready to take a bold stance to make the world better for employees, for consumers, and for the greater community: Read this book.As leaders, you have the unique ability to reach thousands of employees and millions of consumers. It's time for you to build a truly diverse, equitable, and inclusive work environment and, by extension, a more just society.This book provides a comprehensive plan for leaders who are ready to get serious about diversity, equity, and inclusion (DEI) and to create an anti-racist company culture.As a Black man at the highest levels of corporate America for over thirty years, James D. White has built a deep understanding of how to operationalize and integrate DEI agendas. As CEO and Chairman of the global smoothie chain Jamba Juice, he led a remarkable turnaround to make the company a model of strong performance built on a foundation of a diverse, anti-racist culture. He also draws on the experiences of other leaders at the vanguard of DEI. White writes with his daughter, Krista White, who brings to this book the heart and sensibilities of a younger generation devoted to equity and inclusion and intent on justice.Practical lessons and real-world examples of techniques used by seasoned experts will empower leaders who, at this urgent moment, are asking themselves what so many have asked James White: What can I do?You can start by reading this book.

The #1 New York Times bestselling author on how to use radical adaptability to win in a world of unprecedented change.You've shed antiquated systems and processes. You went all-in on digital. Your teams settled into new, often better, ways of doing things. But did your organization change enough to stay competitive in the post-pandemic world? Did you fully leverage the once-in-a-lifetime opportunity to leap forward and grow stronger? Are you shaping the new environment to your advantage?If not, it's not too late to learn from the best.New York Times #1 bestselling author Keith Ferrazzi, along with coauthors Kian Gohar and Noel Weyrich, shows leaders how to shape their organizations and practices to remain competitive in a new, post-pandemic context. Based on an ambitious global research initiative involving thousands of executives, innovators, and changemakers who redefined their strategies, business models, organizational systems, and even their cultures, Competing in the New World of Work:Offers a bold new vision for the organization of the futureReveals the workplace innovations that emerged during the pandemicDefines the new model of leadershipradical adaptabilityfor sustaining continuous change throughout the coming years of opportunity and transformationCompeting in the New World of Work is both your inspiration and your road map to embracing new realities, motivating talent, and winning bold frontiers.