Bøker utgitt av Humana Press Inc.

Leading academic and pharmaceutical researchers and clinicians from many disciplines synthesize and summarize current clinical and basic knowledge concerning abnormal growth of blood vessels in the eye, the cause of major neovascular eye diseases.

This is truly an exciting time in the field of neuro-oncology, particularly in the area of hi- grade gliomas. If the current state-of-the-art in the diagnosis and management of high-grade gliomas was truly so bleak, there would be no reason to compile and publish a monograph on the subject.

Writing in an easy-to-read format-background, diagnosis, and disease management-and emphasizing practical techniques of evaluation and treatment, the authors explain the basic mechanisms underlying cardiovascular disease states and the treatment strategies that arise from them.

Leading expert physicians and investigators from around the world review the state-of-the-art in the management of squamous cell head and neck cancer, with emphasis on coordinating different treatment modalities.

Among the viewpoints up for debate are a consideration of organizations as evil structures, the "medicalization" of evil, destruction as a constructive choice, violence as a secular evil, talking about evil when it is not supposed to exist, and the influence of evil on forensic clinical practice.

The aim of this book is to bring together social scientists, cognitive scientists, psychologists, neuroscientists, neuropsychologists and others to promote a dialogue about the variety of processes involved in social cognition, as well as the relevance of mirroring neural systems to those processes.

Groundbreaking and long overdue, Essential Dance Medicine is a unique text designed to help medical professionals learn the presentations, differential diagnoses and available treatment options for common dance injuries.

Leading clinicians and clinical researchers discuss in practical detail the newest treatments used in rheumatic diseases, emphasizing-without neglecting current standard treatments-those experimental therapies now undergoing clinical trials and poised for early introduction into the rheumatology armamentarium.

Asian Americans are the fastest growing minority group in the United States. In this book, distinguished researchers and clinicians discuss the process of acculturation for individuals and their families, addressing the mental health needs of Asian Americans.

Distinguished researchers and clinicians review the biological and biomedical aspects of gasotransmitters, emphasizing signaling transduction mechanisms in general, and ion channel regulation in particular. The authors discuss the endogeneous metabolism and regulation of gasotransmitters, their toxicological profiles and biological actions, and their interactions in terms of their production and effects. The physiological roles of NO, CO, and H2S in the regulation of the cardiovascular, neuronal, and gastrointestinal systems, as well as of cell metabolism, are also reviewed, along with the interaction of the gastrotransmitters with KATP,KCa voltage-gated Ca2+, voltage-gated Na+, and cyclic nucleotide-gated ion channels.

Opioid research is one of the multidisciplinary research areas that involve advanced techniques ranging from molecular genetics to neuropharmacology, and from behavioral neuroscience to clinical medicine.

Is the involuntary commitment of the mentally ill morally proper? Objective and readily understandable, Mental Illness and Public Health Care illuminates for the educated reader some of the key ethical issues facing mental health care professionals and provides convincing practical conclusions with real moral import.

Offering a wealth of information, this text provides a range of insights, including a novel view of the hormonal regulation of the vascular system and the disruption of the nitric oxide signaling system. It also addresses the role of fatty acids and cytokines.

Part III provides a series of tables providing organ weights and body measurements for fetuses, children and adults.Handbook of Autopsy Practice Fourth Edition is an essential resource for clinicians, pathologists, residents and students who strive to hone their trade and increase the value of the autopsies they perform.

A collection of basic and advanced molecular methods that reveal those markers essential for diagnoses of specific diseases. The techniques range from in vitro methods to in vivo models of prostate cancer, and include new methods for the accurate diagnosis of prostate cancer, and proteome and microarray analyses.

Suicide Gene Therapy: Methods and Reviews covers gene therapy that targets malignant cells in a treatment that has become known as "suicide gene therapy. Additional trials used multiple gene therapy protocols that also involved suicide gene therapy (83 with 497 patients), indicating that the interest in this area is considerable.

We are in an exciting era in the war against cancer, with real prospects for novel anticancer drugs that are cancer cell-specific without the toxicities that have been the hallmark of conventional cytotoxic cancer chemotherapy.

Reviews the findings on the role of folate in human development, health, and disease. This book addresses areas such as folate metabolism in zinc or copper deficiencies, choline and folate in development, animal models of folate-related birth defects, and developmental toxicants potentially acting via folate perturbation.

Presents a survey of the scientific evidence showing how cyclosporin, FK-506, and their analogs - the neuroimmunophilins - evolved from being purely immunosuppressant "drugs" to neuroprotective "agents". This book also discusses their efficacy and mechanisms of action in vitro and in vivo models of CNS disease.

Although the potential applications for such tests at the site of specimen collection, now called "on-site" or "point-of-care" testing, range far beyond hospital emergency rooms and law enforcement needs, it was catalyzed by the requirements of workplace drug testing and other drugs-of-abuse testing programs.

This volume deals with critical issues concerning biocompatible materials - polymers, metals and other substances used in or on the human body. The focus of the topics range from biopolymers used in controlled release drug delivery systems to biopolymeric plates used in bone repair.

A panel of recognized authorities comprehensively review the medical, surgical, and pathophysiologic issues relevant to lung volume reduction surgery for emphysema. The experts also detail the selection of candidates for LVRS, the clinical results and clinical trials in LVRS, and the effects of LVRS on survival rates.

The contributors offer not only an understandable description of its molecular origins-an essential key to developing future therapies and preventive measures-but also rigorously discuss well-tested approaches, as well as those that are currently being evaluated for future use in both the laboratory and clinic.

Seizures are frightening events. Most individuals with seizures present to family physicians or to emergency room physicians. However, despite the fact that seizures are among the most common neurological conditions, most general practitioners, family practice specialists, and intemists do not see large numbers of patients with seizures.

This readily reproducible collection of methods for the study of eicosanoids concentrates on studying the regulation of expression and function of enzymes, particularly cyclooxygenase, phospholipase A2 and lipoxygenases involved in the synthesis of established eicosanoids.

The application of molecular techniques to gastroenterology continues to yield important advances in the development of drugs to treat gastrointestinal disorders.

The authoritative experts writing here explore the mechanistic aspects of such autoimmune diseases as lupus, rheumatoid arthritis, diabetes, and autoimmune thyroid disease, and where possible delineate how malfunctioning immunological mechanisms can lead to clinical symptoms.

The aim of Hematologic Malignancies: Methods and Techniques is to review those methods most useful for the diagnosis and subsequent mana- ment of hematologic malignancies.

In Drug Targeting: Strategies, Principles, and Applications we have tried to compile a state-of-the-art volume on current targeting approaches.

They not only review such problems as obstructive sleep apnea, insomnia, circadian rhythm disorders, and narcolepsy, but they also discuss such important topics as pediatric sleep disorders, the pharmacology of sleep medicines, diagnostic testing and technology, and the use of bright light therapy in sleep disorders and depression.