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Bone grafting is the surgical procedure in which new bone (bone graft) or a replacement material (graft substitute), is placed into bone fractures or bone defects to aid in healing. Bone grafting is in the field of interest of many surgical specialties, such as: orthopedics, neurosurgery, dentistry, plastic surgery, head and neck surgery, otolaryngology and others. In common, all these specialties have to handle problems concerning the lack of bone tissue or impaired fracture healing. There is a myriad of surgical techniques nowadays involving some kind of bone graft or bone graft substitute. This book gathers authors from different continents, with different points of view and different experiences with bone grafting. Leading researchers of Asia, America and Europe have contributed as authors. In this book, the reader can find chapters from the ones on basic principles, devoted to students, to the ones on research results and description of new techniques, experts will find very beneficial.
Epigenetics is one of the most exciting and rapidly developing areas of modern genetics with applications in many disciplines from medicine to agriculture. The most common form of epigenetic modification is DNA methylation, which plays a key role in fundamental developmental processes such as embryogenesis and also in the response of organisms to a wide range of environmental stimuli. Indeed, epigenetics is increasing regarded as one of the major mechanisms used by animals and plants to modulate their genome and its expression to adapt to a wide range of environmental factors. This book brings together a group of experts at the cutting edge of research into DNA methylation and highlights recent advances in methodology and knowledge of underlying mechanisms of this most important of genetic processes. The reader will gain an understanding of the impact, significance and recent advances within the field of epigenetics with a focus on DNA methylation.
The book "Systems Engineering: Practice and Theory" is a collection of articles written by developers and researches from all around the globe. Mostly they present methodologies for separate Systems Engineering processes; others consider issues of adjacent knowledge areas and sub-areas that significantly contribute to systems development, operation, and maintenance. Case studies include aircraft, spacecrafts, and space systems development, post-analysis of data collected during operation of large systems etc. Important issues related to "bottlenecks" of Systems Engineering, such as complexity, reliability, and safety of different kinds of systems, creation, operation and maintenance of services, system-human communication, and management tasks done during system projects are addressed in the collection. This book is for people who are interested in the modern state of the Systems Engineering knowledge area and for systems engineers involved in different activities of the area. Some articles may be a valuable source for university lecturers and students; most of case studies can be directly used in Systems Engineering courses as illustrative materials.
This book is projected as a preliminary manuscript in Infectious Disease. It is undertaken to cover the foremost basic features of the articles. Infectious Disease and analogous phenomenon have been one of the main imperative postwar accomplishments in the world. The book expects to provide its reader, who does not make believe to be a proficient mathematician, an extensive preamble to the field of infectious disease. It may immeasurably assist the Scientists and Research Scholars for continuing their investigate workings on this discipline. Numerous productive and precise illustrated descriptions with a number of analyses have been included. The book offers a smooth and continuing evolution from the principally disease oriented lessons to a logical advance, providing the researchers with a compact groundwork for upcoming studies in this subject.
The accurate measurement of ecosystem biomass is of great importance in scientific, resource management and energy sectors. In particular, biomass is a direct measurement of carbon storage within an ecosystem and of great importance for carbon cycle science and carbon emission mitigation. Remote Sensing is the most accurate tool for global biomass measurements because of the ability to measure large areas. Current biomass estimates are derived primarily from ground-based samples, as compiled and reported in inventories and ecosystem samples. By using remote sensing technologies, we are able to scale up the sample values and supply wall to wall mapping of biomass. Three separate remote sensing technologies are available today to measure ecosystem biomass: passive optical, radar, and lidar. There are many measurement methodologies that range from the application driven to the most technologically cutting-edge. The goal of this book is to address the newest developments in biomass measurements, sensor development, field measurements and modeling. The chapters in this book are separated into five main sections.
This book brings new research insights on the properties and behavior of gamma radiation, studies from a wide range of options of gamma radiation applications in Nuclear Physics, industrial processes, Environmental Science, Radiation Biology, Radiation Chemistry, Agriculture and Forestry, sterilization, food industry, as well as the review of both advantages and problems that are present in these applications. The book is primarily intended for scientific workers who have contacts with gamma radiation, such as staff working in nuclear power plants, manufacturing industries and civil engineers, medical equipment manufacturers, oncologists, radiation therapists, dental professionals, universities and the military, as well as those who intend to enter the world of applications and problems of gamma radiation. Because of the global importance of gamma radiation, the content of this book will be interesting for the wider audience as well.
Basal cell carcinoma is the commonest cutaneous malignancy. The last decade has witnessed exponential research which has broadened our understanding of the pathogenesis of basal cell carcinomas. This is also important from a therapeutic point of view as targeted approach to therapy is now being increasingly experimented. Although it is impossible to condense and present all good research in one book, the authors have to be commended on presenting their research on several aspects of basal cell carcinoma in a succinct manner, which shall not only enhance our understanding of, but also hopefully via this open exchange of ideas pave ways for successful targeted therapy of the commonest human cancer.
Cognitive-behavioral therapy (CBT) is the fastest growing and the best empirically validated psychotherapeutic approach. Written by international experts, this book intends to bring CBT to as many mental health professionals as possible. Section 1 introduces basic and conceptual aspects. The reader is informed on how to assess and restructure cognitions, focusing on automatic thoughts and underlying assumptions as well as the main techniques developed to modify core beliefs. Section 2 of this book covers the cognitive therapy of some important psychiatric disorders, providing reviews of the recent developments of CBT for depression, bipolar disorder and obsessive-compulsive disorder. It also provides the latest advances in the CBT for somatoform disorders as well as a new learning model of body dysmorphic disorder. Two chapters on addiction close this book, providing a thorough review of the recent phenomenon of Internet addiction and its treatment, concluding with the CBT for substance abuse.
Photovoltaics have started replacing fossil fuels as major energy generation roadmaps, targeting higher efficiencies and/or lower costs are aggressively pursued to bring PV to cost parity with grid electricity. Third generation PV technologies may overcome the fundamental limitations of photon to electron conversion in single-junction devices and, thus, improve both their efficiency and cost. This book presents notable advances in these technologies, namely organic cells and nanostructures, dye-sensitized cells and multijunction III/V cells. The following topics are addressed: Solar spectrum conversion for photovoltaics using nanoparticles; multiscale modeling of heterojunctions in organic PV; technologies and manufacturing of OPV; life cycle assessment of OPV; new materials and architectures for dye-sensitized solar cells; advances of concentrating PV; modeling doped III/V alloys; polymeric films for lowering the cost of PV, and field performance factors. A panel of acclaimed PV professionals contributed these topics, compiling the state of knowledge for advancing this new generation of PV.
With an update of the recent progress in etiology, pathogenesis, diagnosis, and treatment of caries, it may be said that the final defeat of dental caries is becoming possible soon. Based on the research in this area in recent decades, "Contemporary Approach to Dental Caries" contained the caries in general, the diagnosis of caries, caries control and prevention, the medical treatment of caries, dental caries in children and others such as secondary caries. This book provides the reader with a guide of progress on the study of dental caries. The book will appeal to dental students, educators, hygienists, therapists and dentists who wish to update their knowledge. It will make you feel reading is profitable and useful for your practice.
Almost a decade has passed since the last textbook on the science of cryobiology, Life in the Frozen State, was published. Recently, there have been some serious tectonic shifts in cryobiology which were perhaps not seen on the surface but will have a profound effect on both the future of cryobiology and the development of new cryopreservation methods. We feel that it is time to revise the previous paradigms and dogmas, discuss the conceptually new cryobiological ideas, and introduce the recently emerged practical protocols for cryopreservation. The present books, "Current Frontiers in Cryobiology" and "Current Frontiers in Cryopreservation" will serve the purpose. This is a global effort by scientists from 27 countries from all continents and we hope it will be interesting to a wide audience.
This book presents recent advances in the field of Neurological disorders research. It consists of 9 chapters encompassing a wide range of areas including bioengineering, stem cell transplantation, gene therapy, proteomic analysis, alternative treatment and neuropsychiatry analysis. It highlights the development of multiple discipline approaches in neurological researches. The book brings together leading researchers in neurological disorders and it presents an essential reference for researchers working in the neurological disorders, as well as for students and industrial users who are interested in current developments in neurological researches.
Progress in agricultural, biomedical and industrial applications' is a compilation of recent advances and developments in gas chromatography and its applications. The chapters cover various aspects of applications ranging from basic biological, biomedical applications to industrial applications. Book chapters analyze new developments in chromatographic columns, microextraction techniques, derivatisation techniques and pyrolysis techniques. The book also includes several aspects of basic chromatography techniques and is suitable for both young and advanced chromatographers. It includes some new developments in chromatography such as multidimensional chromatography, inverse chromatography and some discussions on two-dimensional chromatography. The topics covered include analysis of volatiles, toxicants, indoor air, petroleum hydrocarbons, organometallic compounds and natural products. The chapters were written by experts from various fields and clearly assisted by simple diagrams and tables. This book is highly recommended for chemists as well as non-chemists working in gas chromatography.
Gas Chromatography involves the study of various vaporizable molecules in chemistry and the other related research fields. This analytical method has a number of features and advantages that make it an extremely valuable tool for the identification, quantification and structural elucidation of organic molecules. This book provides detailed gas chromatography information to applications of biochemicals, narcotics and essential oils. The details of the applications were briefly handled by the authors to increase their comprehensibility and feasibility. This guide should be certainly valuable to the novice, as well as to the experienced gas chromatography user who may not have the enough experience about the specific applications covered in this book. We believe this book will prove useful in most laboratories where modern gas chromatography is practiced.
Phytochemicals are biologically active compounds present in plants used for food and medicine. A great deal of interest has been generated recently in the isolation, characterization and biological activity of these phytochemicals. This book is in response to the need for more current and global scope of phytochemicals. It contains chapters written by internationally recognized authors. The topics covered in the book range from their occurrence, chemical and physical characteristics, analytical procedures, biological activity, safety and industrial applications. The book has been planned to meet the needs of the researchers, health professionals, government regulatory agencies and industries. This book will serve as a standard reference book in this important and fast growing area of phytochemicals, human nutrition and health.
Allergic rhinitis, while troublesome for a patient, may be also a challenge for the physician. That is why physicians must still learn more on the pathophysiology, clinical spectrum and novel diagnostic and therapeutic approaches to the disease. The chapters of this volume address a variety of important topics related to allergic rhinitis. They begin with a description of innovative translational approaches allowing for unification of animal and human models. Contributing authors provide up-to-date reviews of clinical aspects of allergic rhinitis in children, its association with bronchial asthma and other co-morbid conditions. They also discuss the impact of allergic rhinitis on sleep and sports. Together with articles on diagnostic approaches as well as novel treatments, the book offers a comprehensive and stimulating review of the topic. May this book find a wide readership among allergists and other physicians interested in allergic disease, and also among pediatricians, general practitioners and other specialists who increasingly have to deal with this seemingly benign, but sometimes extremely troublesome, disease.
An economic viability of a modern day mine is highly dependent upon careful planning and management. Declining trends in average ore grades, increasing mining costs and environmental considerations will ensure that this situation will remain in the foreseeable future. This book describes mining methods for the surface and underground mineral deposits. The methods are generalized and focus on typical applications from different mining areas around the world, keeping in mind, however, that every mineral deposit, with its geology, grade, shape, and volume, is unique. The book will serve as a useful resource for researchers, engineers and managers working in the mining industry, as well as for universities, non-governmental organizations, legal organizations, financial institutions and students and lecturers in mining engineering.
This book, authored by renowned researchers in the field of Hypertension Research, details the state of the art knowledge in genetics, genomics and pathophysiology of Essential hypertension, specifically the genetic determinants of hypertension and role of gene variants in response to anti-hypertensive therapy. Two chapters describe mitochondrial mutations in Essential hypertension and in hypertension associated Left ventricular hypertrophy, one chapter reviews in detail the global gene expression in hypertension, and an up to date treatise on pathophysiology of resistant hypertension is detailed in another chapter. Other topics included in the book are end organ damage, baroreceptor sensitivity and role of music therapy in essential hypertension.
Adaptive E-learning was proposed to be suitable for students with unique profiles, particular interests, and from different domains of knowledge, so profiles may consider specific goals of the students, as well as different preferences, knowledge level, learning style, rendering psychological profile, and more. Another approach to be taken into account today is the self-directed learning. Unlike the adaptive E-learning, the Self-directed learning is related to independence or autonomy in learning; it is a logical link for readiness for E-learning, where students pace their classes according to their own needs.This book provides information on the On-Job Training and Interactive Teaching for E-learning and is divided into four sections. The first section covers motivations to be considered for E-learning while the second section presents challenges concerning E-learning in areas like Engineering, Medical education and Biological Studies. New approaches to E-learning are introduced in the third section, and the last section describes the implementation of E-learning Environments.
Laser scanning technology plays an important role in the science and engineering arena. The aim of the scanning is usually to create a digital version of the object surface. Multiple scanning is sometimes performed via multiple cameras to obtain all slides of the scene under study. Usually, optical tests are used to elucidate the power of laser scanning technology in the modern industry and in the research laboratories. This book describes the recent contributions reported by laser scanning technology in different areas around the world. The main topics of laser scanning described in this volume include full body scanning, traffic management, 3D survey process, bridge monitoring, tracking of scanning, human sensing, three-dimensional modelling, glacier monitoring and digitizing heritage monuments.
Bacteriophages have received attention as biological control agents since their discovery and recently their value as tools has been further emphasized in many different fields of microbiology. Particularly, in drug design and development programs, phage and prophage genomics provide the field with new insights. Bacteriophages reveals information on the organisms ranging from their biology to their applications in agriculture and medicine. Contributors address a variety of topics capturing information on advancing technologies in the field. The book starts with the biology and classification of bacteriophages with subsequent chapters addressing phage infections in industrial processes and their use as therapeutic or biocontrol agents. Microbiologists, biotechnologists, agricultural, biomedical and sanitary engineers will find Bacteriophages invaluable as a solid resource and reference book.
The possibility of getting a cardiovascular disease or cancer increases with advancing age. At the same time, relevant improvements in cancer therapy have resulted in the improvement of quality of life and the increasement of the survival rate of such patients. As a result we have larger number of patients that experience the cardiac side effects of chemotherapy. The extent of cardiotoxicity is variable, depending on the type of drug used, combination with other drugs, prior mediastinal radiotherapy and the presence of cardiovascular risk factors or history of heart disease. Early detection of the patients proneness for developing cardiotoxicity is the key issue to decrease morbidity and mortality. It also facilitates more tailored therapeutic interventions. Therefore, the collaboration and interaction of cardiology and oncology may contribute to reducing the cardiovascular adverse effects and improving the results in the treatment of patients with cancer.
Among the branches of classical physics, electromagnetism is the domain which experiences the most spectacular development, both in its fundamental and practical aspects. The quantum corrections which generate non-linear terms of the standard Maxwell equations, their specific form in curved spaces, whose predictions can be confronted with the cosmic polarization rotation, or the topological model of electromagnetism, constructed with electromagnetic knots, are significant examples of recent theoretical developments. The similarities of the Sturm-Liouville problems in electromagnetism and quantum mechanics make possible deep analogies between the wave propagation in waveguides, ballistic electron movement in mesoscopic conductors and light propagation on optical fibers, facilitating a better understanding of these topics and fostering the transfer of techniques and results from one domain to another. Industrial applications, like magnetic refrigeration at room temperature or use of metamaterials for antenna couplers and covers, are of utmost practical interest. So, this book offers an interesting and useful reading for a broad category of specialists.
Learning disability is a classification that includes several disorders in which a person has difficulty learning in a typical manner. Depending on the type and severity of the disability, interventions may be used to help the individual learn strategies that will foster future success. Some interventions can be quite simplistic, while others are intricate and complex. This book deserves a wide audience; it will be beneficial not only for teachers and parents struggling with attachment or behavior issues, but it will also benefit health care professionals and therapists working directly with special needs such as sensory integration dysfunction.
Achilles tendon has always attracted a great attention. Its disorders include various problems from pain and swelling with bumps to functional impairment or even ruptures. Debates concerning aetiology and optimal treatment are still going on. A lot of efforts and research have already been put on to find the answers to unsolved problems and this book is an attempt to share (some of) these findings to the readers. If only one of the papers helps the therapists or patients in understanding and solving their problems, we will consider that the mission of the book was accomplished.
This book provides a comprehensive overview of the basic and clinical sciences of Systemic Lupus Erythematosus. It is suitable for basic scientists looking for detailed coverage of their areas of interest. It describes how advances in molecular biology have increased our understanding of this disease. It is a valuable clinical resource for practicing clinicians from different disciplines including rheumatologists, rheumatology fellows and residents. This book provides convenient access to information you need about cytokines, genetics, Fas pathway, toll like receptors and atherogenesis in SLE. Animal models have been reviewed as well. How to avoid delay in SLE diagnosis and management, in addition to various clinical manifestations including pregnancy and SLE have all been explained thoroughly in this book.
Cardiovascular disease is ranked as the leading cause of death world wide, responsible for 17.1 million deaths globally each year. Such numbers are often difficult to comprehend. Heart disease kills one person every 34 seconds in the USA alone. Although the leading killer, the incidence of cardiovascular disease has declined in recent years due to a better understanding of the pathology, implementation of lipid lowering therapy new drug regimens including low molecular weight heparin and antiplatelet drugs such as glycoprotein IIb/IIIa receptor inhibitors and acute surgical intervention. The disease burden has a great financial impact on global healthcare systems and major economic consequences for world economies. This text aims to deliver the current understanding of coronary artery disease and is split into three main sections: 1. Epidemiology and pathophysiology of coronary artery disease 2. Coronary artery disease diagnostics and 3. Treatment regimens for coronary artery disease
Sexually transmitted infections (STIs) are infections that are spread primarily through person to person sexual contact. There are more than 30 different sexually transmissible bacteria, viruses and parasites. STIs lead to high morbidity and complications. This book entitled as Sexually Transmitted Infections is not a text book but provides useful information for general reference work for physicians, researchers and students interested in the subject. Each chapter is abundant in tips useful to general readers as well. It also includes the Introductory chapter providing an overview with special emphasis on syndromic approach to the management of STIs in clinical setting.
Information technology has been revolutionizing the everyday life of the common man, while medical science has been making rapid strides in understanding disease mechanisms, developing diagnostic techniques and effecting successful treatment regimen, even for those cases which would have been classified as a poor prognosis a decade earlier. The confluence of information technology and biomedicine has brought into its ambit additional dimensions of computerized databases for patient conditions, revolutionizing the way health care and patient information is recorded, processed, interpreted and utilized for improving the quality of life. This book consists of seven chapters dealing with the three primary issues of medical information acquisition from a patient's and health care professional's perspective, translational approaches from a researcher's point of view, and finally the application potential as required by the clinicians/physician. The book covers modern issues in Information Technology, Bioinformatics Methods and Clinical Applications. The chapters describe the basic process of acquisition of information in a health system, recent technological developments in biomedicine and the realistic evaluation of medical informatics.
The astounding richness and biodiversity of tropical forests is rapidly dwindling. This has severely altered the vital biogeochemical cycles of carbon, phosphorus, nitrogen etc. and has led to the change in global climate and pristine natural ecosystems. In this elegant book, we have defined "Tropical Forests" broadly, into five different themes: (1) tropical forest structure, synergy, synthesis, (2) tropical forest fragmentation, (3) impact of anthropogenic pressure, (4) Geographic Information System and remote sensing, and (5) tropical forest protection and process. The cutting-edge synthesis, detailed current reviews, several original data-rich case studies, recent experiments/experiences from leading scientists across the world are presented as unique chapters. Though, the chapters differ noticeably in the geographic focus, diverse ecosystems, time and approach, they share these five important themes and help in understanding, educating, and creating awareness on the role of "Tropical Forests" for the very survival of mankind, climate change, and the diversity of biota across the globe. This book will be of great use to the students, scientists, ecologists, population and conservation biologists, and forest managers across the globe.The publication of this book was supported by the Secretariat of the Convention on Biological Diversity, United Nations
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