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Nowadays, dye chemistry is a booming area of research. In particular, BODIPY fluorophore dyes are in the spotlight since their chromophore allows the design of tailor-made molecules for specific (bio)technological purposes. BODIPY Dyes: A Privilege Molecular Scaffold with Tunable Properties aims to highlight such chemical versatility and modulable photophysical and electrochemical properties. The second and the third chapter deal with BODIPYs in chemosensing and as labels for bioimaging. The fourth chapter focuses on their electroluminescence and redox properties, and their role in photocatalysis. The fifth chapter provides deeper insight into the degradation mechanisms in acid and basic media. The book aims to overview the state of the art of BODIPYs and inspire readers involved in dye chemistry.

The human body is composed of several systems and organs, consisting of millions of cells that need relatively stable conditions to function and contribute to the survival of the body as a whole. The maintenance of stable conditions for the cells against the variations of the external environment is an essential function of the body and is called homeostasis. As a consequence of the loss of homeostasis, a disease is manifested. This book aims to provide the reader with an up-to-date view of the self-regulatory mechanisms that are activated to achieve homeostasis, the pathways that are altered during the disease process, and how medicine can intervene to restore balance in critical patients.

Celiac disease (CD) occurs in about 1% of people worldwide. Diagnosis rates are increasing due to a true rise in incidence, rather than increased awareness and detection. CD affects genetically susceptible individuals who are triggered by the ingestion of gluten. The disease has many clinical manifestations, ranging from severe to minimally symptomatic or non-symptomatic presentations. Diagnosis requires the presence of duodenal chronic inflammation, and most patients have circulating antibodies against tissue transglutaminase. Our understanding of the basic and clinical aspects of CD increases, which is as a major health problem of almost global occurrence. Case finding, distinguishing CD from other gluten-sensitive conditions, better care, and balanced use of resources are the current challenges.

The electric vehicle and plug-in hybrid electric vehicle play a fundamental role in the forthcoming new paradigms of mobility and energy models. The electrification of the transport sector would lead to advantages in terms of energy efficiency and reduction of greenhouse gas emissions, but would also be a great opportunity for the introduction of renewable sources in the electricity sector. The chapters in this book show a diversity of current and new developments in the electrification of the transport sector seen from the electric vehicle point of view: first, the related technologies with design, control and supervision, second, the powertrain electric motor efficiency and reliability and, third, the deployment issues regarding renewable sources integration and charging facilities. This is precisely the purpose of this book, that is, to contribute to the literature about current research and development activities related to new trends in electric vehicle power trains.

Wetlands include mangroves, peatlands and marshes, rivers and lakes, deltas, floodplains, rice fields, and even coral reefs. It is known that wetlands are ecologically sensitive systems and the most vulnerable of habitats. Anthropogenic activities (urbanization, water uses, land cover changes, industrial activity, pollution, climatic change, etc.) have direct and indirect effects on wetlands. The evaluation of wetlands with a multidisciplinary perspective in environmental sciences and social sciences provides efficient results. Each chapter takes a crucial look at different approaches to the solution by analyzing wetland problems in the laboratory or in the field and collecting data. The purpose of this book is to help researchers, scientists, and decision-makers utilize a methodology appropriate for a specific problem.

The cellular prion protein (PrPC) is expressed as a cell surface protein mainly in the central and peripheral nervous system. The discovery that prions are infectious agents changed the concept of protein synthesis in modern biology and built a bridge between the genesis of infectious and genetic diseases. This book discusses the normal function of the PrPC and its modulatory role in synaptic mechanisms. It describes the pathophysiological processes that accompany TSE - neurotoxicity, loss of anti-inflammatory protective function, neuronal death including prion-induced autophagy and apoptosis, and accumulation of PrPSc in the cytoplasm of neurons. Another aspect outlined here is that some prion diseases show strain variations that determine their development, demonstrating their key role in the development and progression of TSE.

For over 70 years, dengue fever has challenged health systems in every region of the World. It has evolved from a benign febrile illness from the tropics to a major concern in urban settlements, overwhelming health infrastructure with large outbreaks, as it continues to teach us important lessons with its complexities. This book intends to review the latest updates on dengue fever, the tools available for its study and control, and promising technologies currently in the pipeline. With this work, the editors wish to provide students with an updated reference text on the basics of this disease as well as researchers and academics, with a useful document to understand the current outlook and the perspectives for the future.

The aim of An Update in Dental Implantology and Biomaterial is to continue the challenge of reconstruction and implantology into another volume with unique updates. As a surgeon who is usually asked to accomplish the reconstructive skeleton of the rehabilitation plan, questions like "Doc, I am in a hurry, how fast can you finish the treatment?" are becoming very common in practice these days. This phenomenon goes hand in hand with people's current lifestyles. Another challenge is the inapplicable prosthetic plan due to the difficulty at the patient side or the surgical intervention side. The advancement in reconstruction is appreciated, but apparently it has not reached the limit of placing the factors of cost, time, and invasiveness into one location. I believe that cases should be treated and rehabilitated as soon as possible, with reasonable cost and feasible technicality, so that clients can focus on their daily lives. With this book I am honored to present a homogeneous gathering of literature on implantology, elaborated with up-to-date techniques of grafting, the improvement of anterior aesthetics, and answers to questions concerning postoperative implant complications and microbiota care.

Stromal cells are connective tissue cells of any organ, and they support the function of the parenchymal cells of that particular organ. Stromal/stromal stem cells are fundamentally a heterogeneous population of cells with contradictory differentiation potential depending upon their environmental niche. Stromal cell biology is not only intriguing, but equally stromal cell ontogeny in vivo remains challenging. In recent years there has been substantial advances in our understanding of stromal cell biology, especially stromal cell isolation, characterization, differentiation, and interactions in physiological (epithelial-stromal interactions) as well as pathophysiological (stromal-cancer interactions) contexts. In addition, stromal cells are also utilized more and more as a therapeutic tool not only in the field of gene therapy but also in the translational field of tissue engineering and regenerative medicine. Therefore, the goal of this book is to consolidate the recent advances in the area of stromal/stromal stem cell biology covering a broad range of interrelated topics in a timely fashion and to disseminate that knowledge in a lucid way to a greater scientific audience. This book will prove highly useful for students, researchers, and clinicians in stem cell biology, developmental biology, cancer biology, pathology, oncology, as well as tissue engineering and regenerative medicine. This quick reference will benefit anyone desiring a thorough overview of stromal cell structure, function, and its therapeutic implications.

Histology is the science of tissues and as such histology studies cells and tissues of organs using a variety of techniques. Histological techniques are used in different disciplines: research, teaching, and clinical applications. This book explores the research currently being carried out at the molecular, subcellular, and cellular levels, both in normal and pathological processes, from genetic mechanisms to intra- and intercellular signaling. This book includes cutting-edge research reviews and descriptions of technological advances to modify bodily cells and tissues. Targeted at students and researchers in biological, medical, and related disciplines, this book will provide an overview of the work being done in this field, and will highlight gaps and areas that would benefit from further exploration. The book contains eight chapters in four sections and presents reviews in different areas of histology written by experts in their respective fields. Basic histology, cell biology, histopathology, and histological techniques are featured prominently as a recurring theme throughout the chapters. This book will be a most valuable resource for histologists, cell biologists, pathologists, and other scientists alike and contribute to the training of current and future biomedical scientists.

Chemical vapor deposition (CVD) techniques have played a major role in the development of modern technology, and the rise of nanotechnology has further increased their importance, thanks to techniques such as atomic layer deposition (ALD) and vapor liquid solid growth, which are able to control the growth process at the nanoscale. This book aims to contribute to the knowledge of recent developments in CVD technology and its applications. To this aim, important process innovations, such as spatial ALD, direct liquid injection CVD, and electron cyclotron resonance CVD, are presented. Moreover, some of the most recent applications of CVD techniques for the growth of nanomaterials, including graphene, nanofibers, and diamond-like carbon, are described in the book.

The authors have developed models for predicting beach changes applicable to various problems on real coasts. One of them is the contour-line-change model to predict long-term beach changes caused by the imbalance in longshore sand transport, which is a kind of N-line model. Because the calculation of the nearshore current is not needed in this model, and the computational load is small, it has an advantage in the prediction of long-term topographic changes on an extensive coast. However, the handling of boundary conditions becomes difficult when offshore coastal structures are constructed in a complicated manner, and in this regard the so-called 3D model has an advantage. Taking this point into account, the authors developed a morphodynamic model (BG model) by applying the concept of the equilibrium slope and the energetics approach, in which depth changes on 2D horizontal grids are calculated.

Energy conversion technology has always been a main focus for researchers in order to meet the increasing demand as well as securing a clean, consistent and reliable energy supply. The constantly rising fuel price is another good reason to develop alternative systems such as wind turbines, hydropower, photovoltaic systems and other renewable energy solutions. This book contains a collection of selected research works in the areas of electric energy generation, renewable energy sources, hybrid system, electromechanical energy conversion, electric machines, power electronic converters and inverters, energy storage, smart grid and traditional energy conversion systems. The book intends to provide academic and industry professionals working in the field of energy conversion and related applications with an update in energy conversion technology, particularly from the applied perspective.

This book is a marvelous compendium of eight articles that cover a wide range of topics, including breast cancer: management and survivorship, rectal cancer intersphincteric resection, head and neck cancer diagnosis and radiotherapy, synthetic peptides as antitumor agents, and recent advances in thyroid cancer. It has been a wonderful opportunity to co-edit this special edition. We are greatly appreciative of the work of all the contributors to the book, who brought with them tremendous diversity of perspectives and fields truly reflective of the complexity of the topic and who, through coming together in this project, serve as a nidus of the multidisciplinary collaboration in this field. Finally, we must acknowledge the thousands of cancer patients who have participated in the studies that have provided the information that has advanced the field so greatly in recent years.