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The hippocampus is an important brain region, a true central hub for memory of various kinds and other processes. Neuropsychiatric disorders such as Alzheimer's disease, drug addiction, and schizophrenia are characterized by hippocampal alterations. The dentate gyrus of the hippocampus is a site exhibiting adult neurogenesis. This book covers the topic of the hippocampus from various perspectives. It discusses adult neurogenesis, effect of enriched environments on hippocampal plasticity, and long-term potentiation-associated gene expression. The book also addresses multiscale representations of complex environments and strategies in the hippocampus-dependent spatial tasks. Finally, insight into the hippocampus as a link between negative affect and relapse to psychostimulants is provided. The book collects evidence of various hippocampal functions in healthy and disordered brain.

Women with unmet need for family planning are those who are fecund but are not using any method of contraception, not wanting any more children, or wanting to delay the next pregnancy. This notion points to the gap between women?s reproductive intentions and their contraceptive behavior. The need for contraception remains too high. This circumstance is made worse by both a growing population and a shortage of family planning services. It is important that family planning is widely available and easily accessible. This book is intended as an aid to substance that all health workers interested in becoming more effective practitioners will consult on many occasions during their clinical practice. It provides views that the readers can test their experiences against. It presents sound and clear advice on some of the most practical guidance applicable to family planning.

Nano-bioimaging is a real-time observation method for the study of biological processes in subcellular structures and entire cells. This technique aims to interfere as little as possible with life processes using nanoscale materials and probes. In this method, nanoscale photon source is often used for imaging, and 3D structure of the observed specimen is studied in detail without physical interference. Over the last decade, further boost in bioimaging has led to increase the nano-bioimaging impact that includes many improvements in the data analysis method, image processing, and molecular imaging technology. However, to increase the usage of nano-bioimaging, several developments in the field of diagnosis accuracy, photobleaching prevention, and controlling of the fluorescence resonance energy transfer (FRET) must be achieved. The purpose of this book is to provide a perspective on the current status of nano-bioimaging technologies.

Reasoned and based on the difference between discovery and invention, according to the traditional conception, science can be distinguished between basic science and applied science. Nevertheless, we know that the sciences are inseparable. A century or more ago, Louis Pasteur said "there is no applied science, there are applications of science." With this assertion, he establishes the logic of complementarity between them. Science certainly goes beyond its own material application and brings us to issues that have intrigued humanity for a long time. During the many years that we have been working with techniques of material characterization, we observed that this complementarity was not always understood by the researchers. In line with the reasoning that the technique joined with science generates technology, the application of techniques that use x-ray and neutron sources seems to us of fundamental importance for the development of technology. In this way, we present in this book how the existing technology of material characterization can contribute to science and applied technology. The authors who contributed with this book sought to show the importance of applying the existing techniques in the development of their works.

Splines provide a significant tool for the design of computationally economical curves and surfaces for the construction of various objects like automobiles, ship hulls, airplane fuselages and wings, propeller blades, shoe insoles, bottles, etc. It also contributes in the description of geological, physical, statistical, and even medical phenomena. Spline methods have proven to be indispensable in a variety of modern industries, including computer vision, robotics, signal and image processing, visualization, textile, graphic designs, and even media. This book aims to provide a valuable source on splines and their applications. It focuses on collecting and disseminating information in various disciplines including computer-aided geometric design, computer graphics, data visualization, data fitting, power systems, clinical and epidemiologic studies, disease detection, regression curves, social media, and biological studies. The book is useful for researchers, scientists, practitioners, and many others who seek state-of-the-art techniques and applications using splines. It is also useful for undergraduate senior students as well as graduate students in the areas of computer science, engineering, health science, statistics, and mathematics. Each chapter also provides useful information on software developments and their extensions.

This book is a fruit of a collaborative work from several international scientists. It will be a useful resource for researchers, students, and clinicians. Each individual chapter could serve as a prescribed reading for postgraduate students and clinicians specializing in and practicing clinical pharmacology and toxicology, pharmacotherapy and pharmacotherapeutics, pharmacovigilance, and toxicovigilance, as well as those involved in clinical research, drug discovery, and development. Every chapter in this book discusses and provides illustrations on the theme discussed based on authors' understanding and experience while summarizing existing knowledge. In doing so, each chapter provides a new insight that would benefit a novice as well as a seasoned reader in understanding the pharmacokinetic mechanisms and risk factors involved in the occurrence of adverse effects of drugs.

Parkinson's disease (PD) is the second most common neurodegenerative disorder results due to loss of dopamine producing brain cells. Knowledge relating to PD condition has been known since 5000BC, however no effective therapeutic strategies are available till today. Therefore it is important for neurobiologists to work further by taking advantage of modern scientific methods and develop appropriate therapeutic strategies. Efforts in this direction are worthy as they will reduce the burden of PD among elderly, who are already burdened with age related systemic degenerative processes. This book is a humble effort in that progressive direction. It has chapters covering multiple aspects relating to etiology, pathophysiology of PD, available and futuristic therapeutics strategies. Therefore it will be of interest to common man, biomedical researchers and clinicians. This is one small step in a direction "to reduce the burden of neurological disease."

This book is dedicated toward space technology application in Earth studies based on the use of a variety of methods for satellite information classification and interpretation. Advantages of geospatial data use in a large-scale area of observation and monitoring as a source of decision-making stage have been demonstrated. The book describes navigation systems providing data estimation method and review of existing data in the literature relevant to remote sensing sensors delivering main information electromagnetic spectrum and a variety of sensor applications. This aspect is important when combining/integrating satellite data processing into the field measurements. Satellites and satellite data application for the study of Earth features have been demonstrated as the next step of geospatial data application. The use of different purposeful processing technology applications of satellite data is one of the vital aspects of space technology advances. The use of GNSS GPS technology in industry and MODIS images and data interpretation for agriculture purposes has been presented. It was the aim of the book to create an attractive environment by presenting space technology application in the wide areas of Earth study. For this purpose, some of the book chapters are dedicated toward space technology advances in climate monitoring, natural disaster factor detection, satellite data processing optimization, and GIS technology for meteorology information with the aim of agriculture developments.

The book 'Breast Cancer and Surgery' summarizes the treatment options from the onset of breast carcinogenesis to early-local advanced and metastatic breast cancer. Chemotherapy alternatives, drug resistance and local and surgical treatment preferences are extensively discussed and this information is especially directed at clinicians, researchers, and students. This book includes a comparison between different chemotherapy agents and targeted therapies with published phase II-III studies. The importance of palliative care and dietary supplements administered during the treatment course in reducing the comorbidity of patients is emphasized. Photodynamic treatments have been included in this book. A comprehensive and up-to-date information exchange that can be accessed through a single source is provided to all researchers interested in breast cancer.