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Despite abundant conjecture in the scholarly community, and heated rhetoric in state capitols throughout the land, there is remarkably little evidence that state governments can have any effect at all on the economic performance of their states. Working from a broadened historical perspective, and employing political and economic analysis, Paul Brace places the states and their economies in a more understandable light in State Government and Economic Performance. Over time the states have manifested differing degrees of economic activism with notable success. For much of the twentieth century, the dominance of the federal government and the extensive reach of the national economy overwhelmed state-level economic efforts. By the end of the 1970s, however, states began to show greater diversity in their economic performance. Beginning in the Reagan administration, shifting federal priorities and declining resources from Washington forced states to be increasingly self-reliant. In this new, more challenging environment, state-level activism reemerges as an important influence on income growth. The book concerns the economic fortunes of all states, but turns to four case studies to describe in depth how states have responded to economic and political challenges since the 1960s. For example, Arizona and Texas enjoyed booms, but this prosperity was due to forces outside their boundaries. Their traditions of weak government and minimal intervention served them well when the national economy was expanding, yet they were unprepared to stimulate their own economic development in the more challenging environment of the 1980s. Michigan and New York, which initially experienced slow growth, managedto stimulate economic performance because of strong government apparatus and interest - although they too were seriously challenged as the national economy slowed in the early 1990s. These contrasting experiences allow Brace to propose a model for evaluating the economic impact of state government and policy in a changing national economic context. Brace observes that the institutional characteristics of states, the policies they adopt, and their levels of taxation all have statistically discernible effects on their rates of growth in income, but little impact on employment or manufacturing growth. "In essence", he writes, "the institutionally more powerful, entrepreneurial state has been better suited to sustain income in the changing environment of the 198Os". At the same time, however, income growth may serve to retard other forms of growth, most notably in jobs, because of the mobility of capital and labor between the states. Because of this, the states face formidable, even insurmountable, structural barriers to self-sustained economic development. As open economies they are extremely sensitive to competition from other jurisdictions, and ultimately this undermines long-range intervention by the states.

Focusing on Lyotard, Vattimo, and Rorty, Pangle offers a searching critique of postmodernism and its implications for political life and thought. He examines the political dimensions of postmodernist teachings, including the rejection of the natural-rights doctrines of the Enlightenment. "A book to be commended both for its seriousness and its lucidity. . . ".--Stanley Fish, Duke University.

In these new verse translations, Martin makes newly accessible the work of one of ancient Rome's most widely read poets who wrote about the life and language of the people in the streets. (Poetry)

More than a chronicle of different phases in the astronauts' learning process, Before Lift-Off tells the story of the bonding of these men and women.

Your complete resource for handling the physical and emotional effects of breast cancer treatments.At the time of diagnosis, breast cancer patients are faced with many overwhelming decisions about possible treatments. Living with Breast Cancer provides you with an overview of what to expect from testing and treatment, which cancer specialists you may need to see, and common terms to use to help communicate your needs to your team. This empathetic resource full of relatable stories teaches patients and caregivers how to ask the right questions to get the best possible care. The authors explain how to minimize the symptoms and side effects of treatment and outline coping strategies to deal with the stress of breast cancer treatment, including the changes in your body from cancer and its therapies. The book helps readers* make sense of their diagnosis* set goals and prepare for treatment* understand the different types of therapies, tests, and scans* manage the symptoms and side effects of treatment, such as nausea, fatigue, shortness of breath, weight fluctuations, and depression* learn what medications and lifestyle modifications can help with symptoms* live and cope with progressive cancerLiving with Breast Cancer is your definitive resource for handling the physical and emotional effects of breast cancer and treatment.

The untold history of how Chicago served as an important site of innovation in environmental thought as America transitioned to modern, industrial capitalism.In Nature's Laboratory, Elizabeth Grennan Browning argues that Chicago-a city characterized by rapid growth, severe labor unrest, and its position as a gateway to the West-offers the clearest lens for analyzing the history of the intellectual divide between countryside and city in the United States at the end of the nineteenth century. By examining both the material and intellectual underpinnings of Gilded Age and Progressive Era environmental theories, Browning shows how Chicago served as an urban laboratory where public intellectuals and industrial workers experimented with various strains of environmental thinking to resolve conflicts between capital and labor, between citizens and their governments, and between immigrants and long-term residents. Chicago, she argues, became the taproot of two intellectual strands of American environmentalism, both emerging in the late nineteenth century: first, the conservation movement and the discipline of ecology; and second, the sociological and anthropological study of human societies as "e;natural"e; communities where human behavior was shaped in part by environmental conditions. Integrating environmental, labor, and intellectual history, Nature's Laboratory turns to the workplace to explore the surprising ways in which the natural environment and ideas about nature made their way into factories and offices-places that appeared the most removed from the natural world within the modernizing city. As industrialization, urbanization, and immigration transformed Chicago into a microcosm of the nation's transition to modern, industrial capitalism, environmental thought became a protean tool that everyone from anarchists and industrial workers to social scientists and business managers looked to in order to stake their claims within the democratic capitalist order. Across political and class divides, Chicagoans puzzled over what relationship the city should have with nature in order to advance as a modern nation. Browning shows how historical understandings of the complex interconnections between human nature and the natural world both reinforced and empowered resistance against the stratification of social and political power in the city.

"From mRNA vaccines to gene therapies, the next frontier of medical innovation is here. In Building Breakthroughs, Raju Prasad tells the story of important advancements in biotechnology and medical innovation from gene therapies to mRNA vaccines, providing historical context and examining cutting-edge research. Based on in-depth interviews with both the scientists who developed these discoveries and the patients who have benefitted from them, Building Breakthroughs reveals the key players behind drug development and the inner workings of this essential business. Through stories of patients and their families, and of the researchers creating new treatments, Prasad reveals how cell therapies are advancing to treat childhood leukemia and a form of lymphoma, how a gene therapy was established to treat the rare disease spinal muscular atrophy type I, and potentially curative therapies that are being developed for sickle cell disease. By examining the clinical trial and regulatory paths each therapy took to reach approval, Prasad uncovers the building blocks of biotechnology innovation and the investments that must be made to catalyze the development of future breakthroughs. He also explores issues of scientific communication and misinformation, providing recommendations for improvements in the future. For those seeking to understand the vitally important processes that lead to new medicines and the surrounding ecosystem that is enabling the next generation of innovative medicines that have the potential to transform patient outcomes, Building Breakthroughs is essential reading"--