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Presents a bird's-eye view of microwave tubes (MWTs) which continue to be important despite competitive incursions from solid-state devices (SSDs). The book offers a broad and introductory survey to encourage readers to explore the field of MWTs further in selected areas of relevance to their respective interests.

Presents an overview of the concepts, methods, and theories of astrobiology and origins of life research while presenting a summary of the latest findings. The book provides insight into the environments and processes that gave birth to life on our planet, which naturally informs our assessment of the probability that it has arisen (or will arise) elsewhere.

Reviews the essential role of the lateral hypothalamic area (LHA) for the control of body weight, from its historical description as a "feeding centre" to the current view of this LHA as a cellularly heterogeneous hub that regulates multiple aspects of physiology to influence body weight. The authors also evaluate how specific LHA populations coordinate certain metabolic cues and behaviours.

Introduces engineering and science students to the basic underlying physics and chemistry concepts that form the foundation of plasma science and engineering. This is an accessible primer directed primarily at those students who simply do not understand exactly what a plasma or gas discharge is.

The concept of reciprocal space is over 100 years old, and has been of particular use by crystallographers in order to understand the patterns of spots when x-rays are diffracted by crystals. In this book, the author starts with the crystallographer's point of view of real and reciprocal space and then proceeds to develop this in a form suitable for physics applications.

While neutron halos were discovered 30 years ago, this is the first book written on the subject of this exotic form of nuclei that typically contain many more neutrons than stable isotopes of those elements. It provides an introductory description of the halo and outlines the discovery and evidence for its existence. It also discusses different theoretical models of the halo's structure.

How does it happen that billions of stars can cooperate to produce the beautiful spirals that characterise so many galaxies, including ours? This book reviews the history behind the discovery of spiral galaxies and the problems faced when trying to explain the existence of spiral structure within them.

Directly connects the physical world to environmental issues that the world is facing today and will face in the future. This book shows how the first and second laws of thermodynamics limit the efficiencies of fossil fuel energy conversions to less than 100%, while also discussing how clever technologies can enhance overall performance.

The development of nuclear weapons by the Manhattan Project during World War II was one of the most dramatic scientific/technological episodes in human history. This book, prepared by a recognized expert on the Manhattan Project, offers a concise survey of the essential physics concepts underlying fission weapons.The text describes the energetics and timescales of fast-neutron chain reactions, why only certain isotopes of uranium and plutonium are suitable for use in fission weapons, how critical mass and bomb yield can be estimated, how the efficiency of nuclear weapons can be enhanced, how the fissile forms of uranium and plutonium were obtained, some of the design details of the 'Little Boy' and 'Fat Man' bombs, and some of the thermal, shock, and radiation effects of nuclear weapons. Calculation exercises are provided, and a Bibliography lists authoritative print and online sources of information for readers who wish to pursue more detailed study of this fascinating topic.

The electric dipole moment (EDM) challenge measures a non-zero proton EDM value. This book suggests how the challenge can be met. Any measurably large proton EDM would violate the standard model. The method to be employed uses an intense beam of "frozen spin" protons circulating for hour-long times in a storage ring "trap".

Proper vascular development in the placenta is fundamental to ensuring a healthy fetus and successful pregnancy. This book provides an up-to-date summary and synthesis of knowledge regarding placental vascular biology and discusses the relevance of this vascular bed to the functions of the human placenta.

Microelectronics is a challenging course to many undergraduate students and is often described as very messy. This book tries to illustrate the major ideas and the basic analysis techniques, so that students can derive the right equations easily when facing an electronic circuit.

The airways are lined with a film of fluid 10 ?m deep that acts as the first line of defense against inhaled pathogens, dirt, and noxious vapors. In this title, after reviewing the basic structure of mammalian airway epithelium, the author discusses its various defensive functions and how they are altered in airway disease.

Discusses each vasoregulatory phenomena while also considering evidence for their underlying cellular mechanisms. Further, an attempt is made to integrate the information into complex in vivo situations and consider their relevance to pathophysiological situations.

Working with the National Institute of Mental Health (NIMH), the Rutgers Cell and DNA Repository (RUCDR) has begun banking iPSC source cells and converting those source cells into iPSC for distribution to the scientific community. This book provides detailed protocols for reprogramming either fibroblasts with retroviral vectors or cryopreserved lymphocytes with Sendai viral vectors.

Provides a simple approach to understand the essential elements of the angiogenic process, critiques the most powerful angiogenesis assays that are used to discover proangiogenic and antiangiogenic substances, and provides an in-depth physiological perspective on how angiogenesis is regulated in normal, healthy tissues of the human body.

Three distinct types of contractions perform colonic motility functions. Rhythmic phasic contractions (RPCs) cause slow net distal propulsion with extensive mixing/turning over. Infrequently occurring giant migrating contractions (GMCs) produce mass movements. Tonic contractions aid RPCs in their motor function. The spatiotemporal patterns of these contractions differ markedly.

Summarizes our current understanding of the factors involved in the regulation of transcapillary fluid movement, how fluid movements across the endothelial barrier and through the interstitium and lymphatic vessels influence cell function and behaviour, and the pathophysiology of edema formation.

Different regulatory networks are activated in different posterior neural regions, and these networks induce specific neural cell types in each region. Elucidating how each of these networks specify different cell fates is crucial for understanding the basic tenets of how Wnt morphogenetic activity induces the posterior nervous system during the earliest stages of vertebrate development.

The function of the cardiovascular system is strongly affected by the operation of the renal sodium excretion-body fluid volume-arterial pressure negative feedback system that maintains arterial blood pressure at a controlled value over long periods. This volume integrates the basic knowledge of these cardiovascular system components into an understanding of cardiac output regulation.

Reviews the current status of our knowledge of fluid transport across the intestine, including the complexities of transcellular and paracellular ion transport down the length of the intestine and how aberrations of normal physiological processes lead to disease.

Proprotein convertases (PCs) are a family of proteases including PC1, PC2, Furin, PC4, PACE4, PC5, and PC7. This title discusses a number of previous and recent findings on the PCs features, their implication in the regulation of multiple cellular functions that impact on the invasive/metastatic potential of cancer cells, and their clinical relevance in cancer patients.

X-linked adrenoleukodystrophy (X-ALD) is the most common leukodystrophy and the most frequent peroxisomal disorder, with an estimated incidence of 1:17,000. This complex neurodegenerative disorder is characterized by a huge clinical variability both in the age of onset and in symptoms.

Epilepsy affects approximately 3% of the population, and is usually defined as a tendency to experience recurrent seizures arising from periodic neuronal hyperexcitability of unknown causes. Different genetic factors, through various mechanisms, can cause this abnormal neuronal behaviour. The etiology of epilepsy is a major determinant of clinical course and prognosis.

Describes the unique anatomy and physiology of the vascular beds that serve the eye. The need for an unobstructed light path from the cornea to the retina and a relatively fixed corneal curvature and distance between refractive structures pose significant challenges for the vasculature to provide nutrients and remove metabolic waste.

With GIS technologies ranging from Google Maps and Google Earth to the use of smart phones and in-car navigation systems, spatial knowledge is often acquired and communicated through geographic information technologies. This monograph describes the interplay between spatial cognition research and use of spatial interfaces.