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This book discusses challenges for big data predictive toxicology and applications of toxicological big data.

This book examines the European guidelines for the risk assessment and management of serious international public health threats.

Reviewing current understanding of the physical origin and modelling of London dispersion forces, this book is ideal for theoretical, physical and synthetic chemists.

Providing a comprehensive overview, this book is ideal for researchers and industrial chemists working in environmental science, electrochemistry and chemical engineering.

Astrochemistry is a well-established interdisciplinary subject and the methods for describing time-dependent chemistry in static or slowly-changing regions of interstellar space have been well-developed over many years. Existing astrochemical books normally describe the subject in terms of chemistry in static or slowly-varying astronomical situations but the most significant astronomical regions are those in which the physical conditions change on timescales that are comparable to or shorter than chemical timescales. Written by leading experts in this area, this is the first book specifically devoted to the astrochemistry of dynamically evolving astronomical regions. It provides a comprehensive description of this important area of science, stressing in particular the methods that have been developed for specific purposes. It will be of interest to researchers in astrochemistry, including both chemists and physicists and could form the basis of a postgraduate course for research students in chemistry and physics.

This book covers how health is influenced by the consumption of coffee. Aimed at postgraduates and researchers, it provides an impactful and accessible guide to the current research in the field and information for nutritionists and other health professionals.

With a foreword from leading organic chemist Professor Paul Wender, this book collects the major developments reported in the past thirty years in the field of enantioselective reactions promoted by chiral cobalt catalysts.

This book has a strong emphasis on the key challenges in the area for example the biophysics of protein water channels, biomimetics and what we may learn from natural proteins and synthesis and design of highly selective water channels.

This book explores the state-of-the-art of large-scale energy storage and examines the environmental impacts of the main categories based on the types of energy stored.

Nanoscience Volume 5 provides a critical and comprehensive assessment of the most recent research and opinion from across the globe for anyone practising in any nano-allied field, or wishing to enter the nano-world.

This new book focuses on the new developments in the field of amphiphilic polymer co-networks covering the key areas of synthesis, properties, applications and modelling.

Carbohydrate Chemistry is an invaluable volume demonstrating the interdisciplinary nature of modern carbohydrate research and containing analysed, evaluated and distilled information on the latest research in the area.

Data integrity is the hottest topic in the pharmaceutical industry. Global regulatory agencies have issued guidance, after guidance after guidance in the past few years, most of which does not offer practical advice on how to implement policies, procedures and processes to ensure integrity. These guidances state what but not how. Additionally, key stages of analysis that impact data integrity are omitted entirely.The aim of this book is to provide practical and detailed help on how to implement data integrity and data governance for regulated analytical laboratories working in or for the pharmaceutical industry. It provides clarification of the regulatory issues and trends, and gives practical methods for meeting regulatory requirements and guidance. Using a data integrity model as a basis, the principles of data integrity and data governance are expanded into practical steps for regulated laboratories to implement. The author uses case study examples to illustrate his points and provides instructions for applying the principles of data integrity and data governance to individual laboratory needs. This book is a useful reference for analytical chemists and scientists, management and senior management working in regulated laboratories requiring either an understanding about data integrity or help in implementing practical solutions. Consultants will also benefit from the practical guidance provided.

This book reviews the role of plastics in society and examines the environmental impact of different types of plastics.

This book provides a practical approach for using light-emitting sensors and light-driven actuators.

This book covers coffee production, quality and chemistry from the plant to the cup. Aimed at advanced undergraduates, postgraduates and researchers, it provide an impactful and accessible guide to the current research in the field.

This book provides a thorough review of the latest research developments regarding the mechanisms by which oxidative stress and redox signalling mediate Parkinson's Disease.

In the past decade a new era in asymmetric catalysis has been realised by the discovery of L-proline induced chiral enamines from carbonyls. Inspired by this, researchers have developed many other primary catalytic species in situ, more recently secondary catalytic species such as aminals have been identified for use in asymmetric synthesis.High-yielding asymmetric synthesis of bioactive and natural products through mild catalysis is an efficient approach in reaction engineering. In the early days, synthetic chemists mainly focused on the synthesis of complex molecules, with less attention on the reaction efficiency and eco-friendly conditions. Recent investigations have been directed towards the development of atom economy, eco-friendly and enantioselective synthesis for more targeted and efficient synthesis.Building on the momentum of this rapidly expanding research area, Dienamine Catalysis for Organic Synthesis will provide a comprehensive introduction, from the preformed species, in situ generation and onto their applications in the synthesis of bioactive molecules and natural products.

Ideal for professionals working with chemical engineers, and decision makers in chemical engineering industries.

A comprehensive overview of the unique porous silica structure of diatoms, their mechanism of formation, properties and applications.

The volume examines the impact that road vehicles have on the environment, and is vital for policy makers and academics in the field of pollution.

Providing an integrated approach to the various aspects of catalysis, this textbook is ideal for graduate students from catalysis, engineering, and organic synthesis.

Guiding chromatographers working in regulated industries and helping them to validate their chromatography data systems to meet data integrity, business and regulatory needs. This book is a detailed look at the life cycle and documented evidence required to ensure a system is fit for purpose throughout the lifecycle. Initially providing the regulatory, data integrity and system life cycle requirements for computerised system validation, the book then develops into a guide on planning, specifying, managing risk, configuring and testing a chromatography data system before release. This is followed by operational aspects such as training, integration and IT support and finally retirement. All areas are discussed in detail with case studies and practical examples provided as appropriate. The book has been carefully written and is right up to date including recently released FDA data integrity guidance. It provides detailed guidance on good practice and expands on the first edition making it an invaluable addition to a chromatographer's book shelf.

Edited by pioneers in this exciting field, and featuring contributions from leading researchers, this book discusses the principles and applications of XFELs.

Polyurethane nanocomposites present an attractive and sustainable way for designing smart materials that can be used in packaging, health and energy applications.Biobased Smart Polyurethane Nanocomposites brings together the most recent research in the field from the basic concepts through to their applications. Special emphasis is given to sustainable biodegradable polyurethane nanocomposites with hyperbranched architecture. The book introduces biobased polyurethanes and the nanomaterials that can be used as nanocomposites followed by the resulting polyurethane nanocomposites. The second part then explores important applications in paints and surface coatings, shape memory, self-healing, self-cleaning, biomaterials and packaging materials.Written by a leading expert on polyurethane nanocomposites, the book is a great introduction to this smart material and its applications.

A two-volume set providing a comprehensive overview of the applications of ionic liquids as smart materials.

A book useful to postgraduate students and researchers in medicinal chemistry and pharmacology, as well as specialists in the acute brain injury field.

Drug Discovery for Leishmaniasis aims to provide a perspective of the current treatments and their challenges, blended with the emerging strategies and methodologies that will drive new target appraisals and drug developments, as well as addressing the molecular basis of resistance in Leishmania.

This book covers the bioinorganic chemistry of molybdenum and tungsten enzymes and the physicochemical methods that are used to investigate their structure and function.