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This book provides a thorough overview of Bitcoin, cryptocurrencies, and digital assets and their impact on the future of money and finance. It provides a 360-degree practical, concise, and engaging overview of all the topics that one interested about digital assets needs to know including how Bitcoin and Ethereum work, an overview of the most important digital assets in the market, and deep dives into the various types of digital assets including cryptocurrencies, stable coins, CBDCs, utility tokens, security tokens, NFTs, and many others. The book also covers all the essentials including DeFi, crypto mining, crypto regulations, crypto investors, crypto exchanges, and other ecosystem players as well as some of the latest global crypto trends from Web 3.0 and the Metaverse to DAOs and quantum computing. Written by a leading industry expert and thought leader who advises some of the leading organisations in the digital assets space globally, this book is ideal foranyone looking to acquire a solid foundational knowledge base of this fast-growing field and understand its potential impact on the future of money.

In two volumes, this book covers in a comprehensive, internally balanced, systematic and detailed way the field of European Union (EU) banking law and regulation. In three parts, Volume I offers a brief introduction to the role of banks in the contemporary financial system and the theory of banking regulation, a thorough analysis of international financial standards which are contained in the sources of public international banking law (and of public international financial law, in general), a detailed presentation of the gradual evolution and the sources of EU banking law, as well as a precise analysis of the law-making process and the key institutional aspects of this branch of EU economic law. The standards and rules adopted and the institutions created in the aftermath of the (2007-2009) global financial crisis and the subsequent euro area fiscal crisis, as well as during the current pandemic crisis are discussed, as appropriate. A detailed analysis of the substantive aspects ofEU banking law will follow in Volume II

This book offers a complete focus on the radiographic analysis of the abdominal wall and hernias. An estimated 20 million hernias are repaired annually throughout the world. As the technology utilized to complete hernia repairs becomes more complex, surgeons are required to have a more thorough understanding of the radiographic anatomy and diagnostic modalities used to evaluate hernias. Furthermore, the amount that now goes into the preoperative planning of hernias for complex repairs (such robotic and open transversus abdominis muscle release procedures) requires an understanding of radiology and the ability to identify nuances of anatomy offered by the imaging. The use of mesh and extent of re-do hernia repairs has also complicated radiographic evaluation of hernias. The text is a comprehensive review of abdominal wall imaging broken down into individual types of hernia. Each hernia type is discussed with consideration to the best type of imaging evaluation, unique radiographic findings and considerations prior to repair. Representative images, diagrams and videos are used to point out anatomy and features of the hernia. This text offers the first-of-its-kind standardized approach to evaluating hernias radiographically. Most importantly, each hernia and chapter is approached with the surgeon in mind, meaning, authors explain the radiology based on anatomy and with a plan for surgical repair on the horizon. Select chapters include illuminating videos to give context to the text. This is an ideal guide for practicing surgeons and trainees treating patients with hernias.

Reinforcement learning is a learning paradigm concerned with learning to control a system so as to maximize a numerical performance measure that expresses a long-term objective. What distinguishes reinforcement learning from supervised learning is that only partial feedback is given to the learner about the learner's predictions. Further, the predictions may have long term effects through influencing the future state of the controlled system. Thus, time plays a special role. The goal in reinforcement learning is to develop efficient learning algorithms, as well as to understand the algorithms' merits and limitations. Reinforcement learning is of great interest because of the large number of practical applications that it can be used to address, ranging from problems in artificial intelligence to operations research or control engineering. In this book, we focus on those algorithms of reinforcement learning that build on the powerful theory of dynamic programming. We give a fairly comprehensive catalog of learning problems, describe the core ideas, note a large number of state of the art algorithms, followed by the discussion of their theoretical properties and limitations. Table of Contents: Markov Decision Processes / Value Prediction Problems / Control / For Further Exploration

This volume provides a collection of protocols from researchers in the statistical genomics field. Chapters focus on integrating genomics with other ¿omics¿ data, such as transcriptomics, epigenomics, proteomics, metabolomics, and metagenomics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and thorough, Statistical Genomics hopes that by covering these diverse and timely topics researchers are provided insights into future directions and priorities of pan-omics and the precision medicine era.

This detailed volume provides methods that can be used to study dendritic cell (DC) ontogeny, isolation, migration, and functions. After an introduction to murine and human DC subsets and their unique transcriptional, phenotypic, and functional properties, the book continues with sections covering in vivo studies, in vitro differentiation, enrichment, functional characterization, as well as Omics approaches to study dendritic cells. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Dendritic Cells: Methods and Protocols is an ideal guide to familiarize readers with the current state of the art techniques to investigate these vital cells.

This edition provides a collection of state-of-art methods and tools for human leukocyte antigen (HLA) and major histocompatibility complex (MHC) research. The book explores updated as well as novel in silico tools, resources, and wet lab protocols for HLA typing, including determination of the HLA class I and class II type of an individual in clinical work and research, such as in transplantation medicine and vaccine development in the context of infectious diseases or cancer immunotherapies. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detailed information and implementation advice that leads to best results. Up-to-date and practical, HLA Typing: Methods and Protocols, Second Edition serves as a valuable resource for any researcher interested in learning more about this vital field.

This fully updated volume explores notable developments in the field of mammalian cell-based recombinant protein production. Beginning with methods for transient recombinant protein production, the book continues with methods for stable cell pool generation, protein production using stable clonal cell lines, as well as high-throughput screening technologies for characterizing transient cell surface protein ectodomain expression and for identifying host genes involved in protein production. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Recombinant Protein Expression in Mammalian Cells: Methods and Protocols, Second Edition serves as an ideal guide for researchers investigatingprotein structure and function and accelerating the discovery of new therapeutic proteins.

Fluorescence is the most popular technique in chemical and biological sensing and this book provides systematic knowledge of basic principles in the design of fluorescence sensing and imaging techniques together with critical analysis of recent developments. Its ultimate sensitivity, high temporal and spatial resolution and versatility enables high resolution imaging within living cells. It develops rapidly in the directions of constructing new molecular recognition units, new fluorescence reporters and in improving sensitivity of response, up to the detection of single molecules. Its application areas range from the control of industrial processes to environmental monitoring and clinical diagnostics. Being a guide for students and young researchers, it also addresses professionals involved in basic and applied research. Making a strong link between education, research and product development, this book discusses prospects for future progress.

This book provides an accessible way into the ideas of Basil Bernstein. It introduces, explains and exemplifies key conceptual landmarks in the development of his theory, from his sociolinguistics in the 1960s through analyses of classrooms and the construction of curriculum in the 1970s and 1980s, to studies of intellectual fields of research through the 1990s. The book introduces how these ideas can and have been used in empirical research over the past fifty years, and how they are being built on by scholars in the twenty-first century to create a cumulative approach to understanding education, knowledge and society that is alive and growing today. ¿

This book explores the causes of rising income inequality within industrialised, developing, and emerging economies. The development of finance capitalism over the last 40 years is charted to highlight how the neoliberal restructuring of national and global economies has driven income inequality. With case studies from the USA, South Korea, Argentina, and Sweden, a comparative analysis is presented to reveal how financialisation facilitates uneven capital accumulation and generates conditions that increase income inequality.This book aims to outline an analytical framework for a financialisation-induced income inequality nexus. It will be relevant to students and researchers interested in the political economy and financial economics.

This book serves as a quick reference for all dentists who perform physical exam before the sedation and treatment of pediatric patients. In the dental care setting, pediatric patients present unique challenges to proper sedation and management of dental pathology. A prior history and physical exam is often absent. Learning how to properly conduct a history and physical exam on Pediatric patients is an essential skill for dentists, and has significant implications for parents, patients, and our healthcare system. This book aims for a comprehensive coverage of the review of systems, improve patient care and identify possible complications in pediatric sedation.Each chapter will focus on a single system, discussing its important features and difficulties, and highlighting implications for the dental management. The book includes checklists for practitioners as they go through the physical exam of a pediatric patient, and helps to adequately prepare for comprehensive dental treatment. It includes contributions by leading experts in the field and is structured for quick reference making it a necessary tool in every dental office. This book will bridge the gap between the dental and medical professionals when it comes to the history and physical of the pediatric patient.

This contributed volume identifies how the information processes of public institutions and citizens have changed throughout the COVID-19 pandemic, within a new context that emerged: the infodemic disorder. Public debate is largely characterized today by a crisis of the legitimacy of institutions, accompanied by a crisis of authority in public communication, leading to the emergency of a state of information disorder due specifically to the need to find information related to the coping of the pandemic. This condition is characterized by growing attention to issues related to ¿fake news¿, ¿misinformation¿, and ¿media manipulation¿, that are intertwined in digital platform ecosystems, and the effects of which on democracy, public communication and research, and the sharing of information in the civic sphere are broad and far-reaching. This volume analyzes the links between communication strategies of public institutions, and the resulting citizen communication, in an attempt to tease out how communication processes have changed during the pandemic. It was decided to investigate this infodemic disorder as it appeared in three different geographical contexts: Europe, Canada and Mexico and, at the same time, to bring out the formal and informal coping strategies implemented by public institutions and citizens. Beginning with an introduction to the crisis of information created by the pandemic, the contributors build a theoretical framework, provide contagion data, and subsequently, for each of the geographical contexts analyzed, explore the public communication strategies and those activated by citizens seeking to share information.

This book considers the differential occurrence and impact of deviance and dysfunction on family firms. The author argues that how family systems develop in family, cultural, and societal contexts, strongly affects differences in the types and levels of negative behaviours in family firms. By considering the context of recent developments and extensions in family systems theory, this book will guide future research investigating the impact of broader definitions of family to consider socio-legal, social-biological, and role-based families. It provides a retrospective look that lays the groundwork for a future research agenda that can blend and develop current management theory as it relates to family firms with the latest developments in family systems theory.

This book presents oral histories from the last surviving UK veterans of the Korean War. With the help of the UK National Army Museum and the British Korean Society, this book collects nearly twenty testimonials of UK veterans of the Korean War. Many only teenagers when mobilized, these veterans attempt to put words to the violence and trauma they experienced. They recall the landscape and people of Korea, the political backdrop, and touching moments in unlikely situations. Like other oral histories of war, their stories recount friendship, hardship, the loss of innocence, and the perseverance of humanity in the face of cruelty. The testimonies were taken by academics and students from the University of Roehampton, and supported by the National Army Museum and the British Korean Society. Through their memories we learn a great deal about the conflict in macro and micro scales.

The Present Volume aims to summarize and update the information on utilization of soil microbes for management of plant parasitic nematodes. This volume will include more than 16 high quality chapters dealing with paradigms and mechanisms of nematode management using soil microbes, various soil microbes and their effectiveness in management of certain nematode diseases and regional case studies/success stories and lessons learnt for nematode management in various crops across the globe.Written for researchers, academicians, scientists, working in the field of Plant nematode management.