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This book assesses the most appropriate forms of aerosol therapy for critically ill patients. Aerosol therapy is applied for the treatment of several pulmonary diseases in addition to some promising applications intended for systemic absorption. Nowadays, aerosol delivery to clinically stable patients in the outpatient settings is done easily with a lot of focus on patient counseling and enhancement of lung deposition. A lot of guidelines are available for several diseases and it could offer adequate guidance to the therapists concerning escalation or de-escalation of therapy to enhance treatment efficiency and safety. However, in critically ill patients aerosol delivery is mostly done by the choice of the respiratory therapist only according to his knowledge. The book describes the type of patients requiring aerosol therapy, different aerosol generators available for the treatment of critically ill patients, mechanisms of aerosol lung deposition, and factors affecting aerosol deposition. It also discusses the special needs of neonates and infants, transitioning aerosol from hospital to home, and the methods of aerosol delivery to different patient e.g. nasal delivery patients, ventilated patients, etc. Moreover, it reviews methods of detecting such aerosol delivery to the lung. At the end, it discusses the suggested monitoring plans and weaning protocols to ensure high efficacy and safety of the ventilatory support in such patients. Given its scope, the book can serve as guidelines or specific recommendations to maximize clinical benefits of medicated aerosols in critically ill patients and it represents a valuable resource for intensivists, pulmonologists and healthcare professionals working at ICUs.

Return to training (RTT) and return to play (RTP) decisions making process in football are currently based on expert's opinion. However, there are no consensus guidelines on evidence-based decision-making. This book provides a framework for evidence-based decision-making both in RTT and RTP following lower-limb muscle injuries sustained in football.Based on the ¿Italian Consensus Conference (2019) on return-to-play after lower limb muscle injury in football¿, it provides a list of RTT and RTP criteria after such injuries compiled by orthopedic surgeons, sports physicians, radiologists, rehabilitation physicians, sport physiologists, general surgeons, family physicians, physiotherapists, physical trainers and psychologists working in elite football in Italy.The book identifies the main criteria for RTT and RTP following injuries involving the most important muscle groups, i.e. quadriceps, hamstring, hip adductor, hip external rotator, iliopsoas and soleus-gastrocnemius.As such it is a valuable reference resource for practitioners making RTT and RTP decisions making process.

This book provides a reference and contextual basis for depression, burnout and suicide among oncology and other medical professionals. Oncology as a medical subspecialty is at a unique apex of this crisis. While the same pressures in medicine certainly apply to oncologists, oncology is particularly stressful as a changing field with diverse patient and societal expectations for outcomes. In addition to experiencing the stress of caring for patients that could succumb to their cancer diagnoses, these professionals are regularly confronted with an onslaught of new medical information and a landscape that is changing at a breakneck pace. These are just a few factors involved in the increasing rates of burnout among oncologists as well as other medcial professionals. By addressing a gap in identifying mental health problems among health care professionals, this book sheds light on mental health problems and suicide among physicians. Importantly, this book is a call to action of the professional and administrative organizations to work on improving mental health of physicians. Anxiety and depression affect not only the individual doctor but also patient care. Given the increasing attention to these issues along with limited yet applicable data regarding how to address these issues, the text aims to bring the latest data face to face with consensus opinion and can be used to ultimately enhance oncologic and psychiatric practices. Written by experts in the field, Depression, Burnout and Suicide in Physicians: Insights from Oncology and Other Medical Professions aims to significantly increase awareness and contribute to understanding the necessity of preventive measures on individual, family, and care givers levels.

Neuromodulation implants are currently one of the most successful techniques in the treatment of chronic pain, a condition that affects more and more patients each year, leading to reduced quality of life as well as economic losses.Neuromodulation implants for pain are a relatively new technique and are being increasingly used around the globe. However, technical training is not available for every implanter as there are relatively few centers in the world. Further, refresher courses for low-rate implanters are not available. This book fills that gap by offering an update on the best techniques currently used, providing a step-by-step guide on how to perform these procedures correctly. Based on the experiences of leading physicians in the field, it also discusses how to manage both major and minor complications. Lastly, it covers the neuromodulatory intervention techniques used to treat chronic pain in various clinical areas. As such it is a valuable resource for pain physicians as well as neurosurgeons, orthopedists and anesthetists.

This comprehensive book offers an overview of the latest advances in knee ligament and knee preservation surgery, including cartilage, meniscus, and osteotomy procedures.Designed to offer practical guidance on the management of complex knee problems, it presents clinical scenarios as well as recommendations by leading international experts. Written in collaboration with ISAKOS and drawing on a variety of perspectives it is invaluable tool for orthopedic and sports medicine surgeons.

This book presents the evidence related to the use of injectable biologics to provide faster and better healing for musculoskeletal lesions and conditions. The authors discuss approaches, such as blood derivatives and cell concentrates, applied to lesions of muscles, ligaments, tendons, bones, meniscus and cartilage, as well as osteoarthritis. Chapters are written by some of the most influential opinion leaders in the field, with up-to-date review of the current literature, where the authors explore both the potential and the limitations of these minimally invasive and promising treatments.The first section is devoted to the formulations and rationale for the use of injectable orthobiologics, while the second section reviews current treatment methods applied to specific joints and pathologies ¿ ranging from tendinopathies through non-unions to articular degenerative processes ¿ as well as the results of these treatment approaches. The third section explores future perspectives, such as pluripotent stem cells, gene therapy, and the stimulation of intrinsic stromal cell niches. Appealing to a broad readership, this book will be of interest to both laboratory research scientists and clinicians, including orthopedists, sports physicians, physiatrists, and regenerative medicine experts.

Urticaria is one of the most common diseases encountered in dermatology. The fleeting nature of wheals often makes a first diagnosis by both patients and physicians seem easy. The disease itself is of a highly complex nature, with a variety of clinical manifestations ranging from pinpoint sized wheals to extensive angioedema. Further complexities include the diversity of possible eliciting and aggravating factors, the many different clinical subtypes and the therapeutic responsiveness.This second, extensively revised edition includes the indications listed in the most recent international guidelines, provides a practical, comprehensive review of all clinical aspects and causes, and addresses the diagnosis and therapy of different types of urticaria. Specific chapters are devoted to classification, aetiopathogenesis, patient reported outcomes, acute urticaria, chronic urticaria and its comorbidities, angioedema without weals, inducible urticarias, special populations including children, treatment with antihistamines and omalizumab, other interventions and looking ahead to new therapies. This new edition is a must read for dermatologists, allergists, pediatricians and practitioners of all disciplines who want their patients to benefit from cutting-edge diagnostics and treatments.

Peripheral nerve issues are potential sequalae of orthopedic surgery, even after cases in which technically excellent surgery was performed. These injuries can impede the expected recovery of function after the primary surgery. Given the manifold challenges associated with recovery of peripheral nerve injuries, this book is designed as a multidisciplinary guide to the diagnosis, prognostication and treatment of peripheral nerve issues after common orthopedic surgeries. Beginning with an overview of nerve compression, injury and regeneration, as well as a presentation of the current diagnostic and imaging modalities for peripheral nerve injuries, this unique text is organized by anatomic region and by type of procedure performed. Topics covered include shoulder and elbow arthroplasty and arthroscopy, fractures of the hand and wrist, hip preservation surgery, total knee replacement, open surgery of the foot and ankle, lumbosacral myeloradiculopathy, and more. Each chapter is authored by both a subspecialty surgeon who routinely performs the surgeries described and a subspecialized hand/peripheral nerve surgeon with experience in evaluating and treating nerve issues after that particular injury. Emphasis is placed on multidisciplinary team approaches, patient counseling, and technical aspects of surgical treatment. Generously illustrated and written by experts in the field, Peripheral Nerve Issues after Orthopedic Surgery is a truly interdisciplinary resource for orthopedic, plastic, hand and trauma surgeons, physiatrists, trainees, and all professionals evaluating and managing postoperative peripheral nerve issues.

This book provides a focused resource on how cardiac surgery capacity can be developed and how it assists in the sustainable development and strengthening of associated health systems. Background is provided on the extent of the problems that are experienced in many nations with suggestions for how suitable frameworks can be developed to improve cardiac healthcare provision. Relevant aspects of governance, financial modelling and disease surveillance are all covered. Guidance is also given on how to found and nurture cardiac surgery curriculum and residency programs.Global Cardiac Surgery Capacity Development in Low and Middle Income Countries provides a practically applicable resource on how to treat cardiac patients with limited resources. It identifies the key challenges and presents strategies on how these can be managed, therefore making it a critical tool for those involved in this field.

This book gathers a collection of cases with challenging diagnoses, in which nuclear medicine examinations have been particularly helpful in terms of the final diagnosis or follow-up. The cases presented chiefly involve patients with neurodegenerative disorders, epilepsy and brain tumors. The book is intended for nuclear medicine specialists as well as clinicians, offering essential guidance on the interpretation of neurology cases in the clinical setting, particularly with regard to correctly interpreting diagnostic imaging procedures. The authors were selected from the members of the Neuroimaging Committee of the EANM and have extensive experience as clinicians and teachers within the Nuclear Medicine Community.

This book presents the latest evidence-based guidelines for perinatal management and is designed to help obstetricians and neonatologists minimize complications and offer patients the best possible care.Since 1960, there has been a significant increase in basic and clinical investigations on normal and pathological pregnancy in the developed world. This has provided insights into the physiopathology of pregnant women, fetuses and newborns and led to the development of new technologies, bringing about a new medical subspecialty: perinatal medicine. The book is divided into eight main sections: The first examines basic periconceptional care and discusses the ethical aspects of perinatology. The next section focuses on prenatal considerations, such as the nutritional aspects of gestation and puerperium, physical exercise during pregnancy, routine laboratory tests, prenatal care of multiple gestations and the role of the neonatologist in prenatal care. The third and fourthsections then explore fetal evaluation, and clinical intercurrences in pregnancy, respectively. The next section addresses pregnancy complications: prevention, diagnosis and management. The sixth section covers the basic aspects of congenital infections and the seventh examines labor and delivery aspects. Lastly, the final section includes chapters on neonatal assistance.Written by leading experts in obstetrics, neonatology, and perinatology, this thoroughly updated, comprehensive resource reflects the latest information in all areas, including genetics and imaging.

This book provides up-to-date and practical knowledge in all aspects of whole slide imaging (WSI) by experts in the field. This includes a historical perspective on the evolution of this technology, technical aspects of making a great whole slide image, the various applications of whole slide imaging and future applications using WSI for computer-aided diagnosis The goal is to provide practical knowledge and address knowledge gaps in this emerging field. This book is unique because it addresses an emerging area in pathology for which currently there is only limited information about the practical aspects of deploying this technology. For example, there are no established selection criteria for choosing new scanners and a knowledge base with the key information. The authors of the various chapters have years of real-world experience in selecting and implementing WSI solutions in various aspects of pathology practice. This text also discusses practical tips and pearls to address the selection of a WSI vendor, technology details, implementing this technology and provide an overview of its everyday uses in all areas of pathology. Chapters include important information on how to integrate digital slides with laboratory information system and how to streamline the ¿digital workflow¿ with the intent of saving time, saving money, reducing errors, improving efficiency and accuracy, and ultimately benefiting patient outcomes.Whole Slide Imaging: Current Applications and Future Directions is designed to present a comprehensive and state-of the-art approach to WSI within the broad area of digital pathology. It aims to give the readers a look at WSI with a deeper lens and also envision the future of pathology imaging as it pertains to WSI and associated digital innovations.

This book is an academic and practical guide to the diagnostic methods and management strategies for both common and rare scrotal diseases. Chapters focus on the normal anthropometric measures of the scrotum as a unique organ and the latest relevant advancements in the field. Techniques including scrotal reconstruction for congenital abnormalities, trauma, and cancer-related extirpation are all covered. Critical tools and methods related to aesthetics are also detailed. Emphasis is also placed on identifying common pitfalls and how to avoid them, ensuring that the reader is fully equipped to deal with a range of scenarios.Normal and Abnormal Scrotum describes how to approach diagnosing and managing the entire range of scrotal diseases, making it essential for all general practitioners, pediatricians, urologists, and pediatric and aesthetic surgeons who encounter these patients in their day-to-day practice.

Utilizing clinical case material of children with diabetes insipidus (DI), this concise, practical pocket guide will provide clinicians with the best real-world strategies to properly diagnose and manage the various manifestations of the disorder they may encounter. It presents a detailed cross-section of pediatric patients, with different etiologies of the disease and possible complications, to provide sensible management scenarios to physicians treating patients with DI. The cases presented include diagnostic strategies and radiological findings for familial and nephrogenic DI as well as DI resulting from hypophysitis, germ cell tumors, Rathkes Cleft Cysts, Langerhans Cell Histiocytosis, craniopharyngiomas, genetic causes, and congenital malformations. Each case focuses on a specific learning objective with clinical pearls, and together these cases represent a comprehensive understanding of children with DI from many aspects.Managing pediatric patients with DI isa threefold challenge of determining the diagnosis, etiology and treatment. Pragmatic and reader-friendly, Diabetes Insipidus in Children is an excellent resource to assist endocrinologists and other clinicians caring for patients with this disease.

This book is written for providers of broad training backgrounds, and aims to help those who care for people with EDs, overweight and obesity provide evidence-based care. The goal of the book is to provide these providers with a straightforward resource summarizing the current standard of care. However, it goes further by also introducing the concept of food addiction (FA) as a model to understand some forms of overeating. This book discusses the pros and cons of embracing FA and reviews the evidence for and against the validity and utility of FA. By doing so, the chapters convey a ¿middle ground¿ approach to help people with obesity, BED, and bulimia nervosa plus FA symptomatology who also want to lose weight. The text discusses FA by reviewing several of the main ongoing controversies associated with the construct. It reviews both the clinical and neuroscientific evidence that some individuals¿ eating behavior mirrors that seen in substance use disorders (SUD), such as how their relationship with food appears to be ¿addictive¿. Chapters also discuss how many of the mechanisms known to underlie SUDs appear to drive overeating in animal models and humans. Finally, the text argues that the similarities between the brain mechanisms of addictive disorders and overeating behavior has the potential to open up new avenues for current treatment and treatment development. Food Addiction, Obesity and Disorders of Overeating: An Evidence-Based Assessment and Clinical Guide is suited for both medical and mental health practitioners, including physicians in primary care or psychiatry, nurses, psychologists, social workers, medical students and medical residents. It could also be utilized by researchers in obesity and ED fields, stimulating ideas for future research and study design.

This user-friendly, pragmatic book discusses the normal and pathological conditions of the appendicular skeleton, with a focus on the preservation of joint function, providing a detailed overview of strategies for both common and complex joint preservation.The first section covers basic topics, ranging from joints homeostasis and biomechanics, to genetics, bio-orthopedics, tissue engineering and 3D bioprinting. The following sections are each dedicated to a specific joint ¿ its functional anatomy, pathologic conditions, diagnostics and treatment.This book is of interest to orthopedists and sports medicine specialists treating common and complex injuries of the joints.

This book is devoted to COVID-19 associated coagulopathy, one of the main determinants of mortality. The volume, intended as a guide, will lead the reader in a pathway starting from pathophysiology and passing through laboratory data, clinical aspects, imaging, and therapeutic options. Written in the middle of the second wave, the book is the first addressing the topic and summarizing the results of studies and articles meanwhile published, thus representing a unique tool for clinicians fighting the disease. The Coagulation Labyrinth of Covid-19 is intended for clinicians working with acute and sub-acute ARDS cases: intensivists, anesthesiologists, cardiologists, hematologists, who will find in it an essential guide to manage the COVID-19 pandemic.

This concise and handy book offers practical guidance to orthopedic surgeons and residents willing to master knee arthroscopy techniques in their daily practice. Based on scientific evidence but also mirroring expert know-how and best practices, it equips readers with essential information, tips and tricks to avoid and prevent intraoperative minor and major complications.Clearly and uniformly written, and featuring a wealth of intraoperative pictures, the book guides readers step-by-step through each of the presented arthroscopic procedures ¿ from patient positioning, through meniscal suture approaches and hamstring grafting, to ACL, PCL and MPFL reconstructions.Covering all the basic and practical aspects this book is a must-read for residents and young orthopedic surgeons wanting to gain insights into this surgical technique and valuable tool for practicing orthopedists, sports physicians and physiotherapists with an interest in knee arthroscopy.

This updated volume provides a clinical based overview of the assessment and treatment of ADHD in adults by a clinical researcher with extensive experience. Its practical focus allows each chapter to answer common questions encountered within clinical practice. Differential diagnosis of ADHD is also discussed in relation to comorbidity with bipolar disorder, borderline personality disorder, chronic fatigue syndrome, and chronic delayed sleep phase. Adult ADHD: Diagnostic Assessment and Treatment, fourth edition aims to help readers identify ADHD effectively and put in place suitable treatments. The book is relevant for psychiatrists, neurologists, and healthcare professionals involved in the diagnosis and treatment of adult ADHD.