Muscarinic Receptors in Airways Diseases

Cholinergic and noncholinergic parasympathetic control of airway smooth muscle.- Role of non-neuronal and neuronal acetylcholine in the airways.- Identification, localization and function of muscarinic receptor subtypes in the airways.- Functional roles of postjunctional muscarinic M2 receptors in airway smooth muscle.- Dysfunction of prejunctional muscarinic M2 receptors: role of environmental factors.- Muscarinic receptor-?-adrenoceptor cross-talk in airway smooth muscle.- Gene regulation of muscarinic receptor subtypes.- Muscarinic control of airway mucus secretion.- The role of anticholinergics in asthma and COPD.- Novel perspectives in anticholinergic therapy.